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Biology and Biochemistry

D-Index
71
Citations
13772
World Ranking
6809
National Ranking
3142

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Adam Zlotnick is affiliated with Indiana University in the United States. Their research spans multiple fields with a primary focus on Medicine and Environmental Science. Within these domains, they have contributed notably to subfields including Ecology, Epidemiology, Infectious Diseases, Hepatology, and Molecular Biology.

The scientist's scholarship emphasizes several core topics of study. These include:

  • Bacteriophages and microbial interactions
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Viral gastroenteritis research and epidemiology
  • Protein Structure and Dynamics
  • Endoplasmic Reticulum Stress and Disease
  • Plant Virus Research Studies

Adam Zlotnick has frequently published in prominent venues, with the most recurrent being:

  • Journal of the American Chemical Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Analytical Chemistry
  • ACS Nano
  • Science Advances

The researcher has collaborated extensively with peers such as Martin F. Jarrold, Christopher J. Schlicksup, Joseph Che-Yen Wang, Stephen C. Jacobson, and Zhongchao Zhao.

Some of their significant recent papers include:

  • The unique potency of Cowpea mosaic virus (CPMV) in situ cancer vaccine, 2020, Biomaterials Science
  • Higher Resolution Charge Detection Mass Spectrometry, 2020, Analytical Chemistry
  • Nomenclature of HBV core protein-targeting antivirals, 2022, Nature Reviews Gastroenterology & Hepatology
  • Rapidly Forming Early Intermediate Structures Dictate the Pathway of Capsid Assembly, 2020, Journal of the American Chemical Society
  • Viral structural proteins as targets for antivirals, 2020, Current Opinion in Virology

In recognition of their scientific contributions, Adam Zlotnick was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2017.

Best Publications

  • Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy

    J F Conway;N Cheng;A Zlotnick;P T Wingfield

  • Weak protein-protein interactions are sufficient to drive assembly of hepatitis B virus capsids.

    Pablo Ceres;Adam Zlotnick

  • A Theoretical Model Successfully Identifies Features of Hepatitis B Virus Capsid Assembly

    Adam Zlotnick;Jennifer M. Johnson;Paul W. Wingfield;Stephen J. Stahl

  • To Build a Virus Capsid: An Equilibrium Model of the Self Assembly of Polyhedral Protein Complexes

    Adam Zlotnick

  • Dimorphism of Hepatitis B Virus Capsids Is Strongly Influenced by the C-Terminus of the Capsid Protein

    A Zlotnick;N Cheng;J F Conway;F P Booy

  • Mechanism of capsid assembly for an icosahedral plant virus.

    Adam Zlotnick;Ryan Aldrich;Jennifer M. Johnson;Pablo Ceres

  • A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly

    Stephen J. Stray;Christina R. Bourne;Sreenivas Punna;Warren G. Lewis

  • Model-based analysis of assembly kinetics for virus capsids or other spherical polymers.

    Dan Endres;Adam Zlotnick

  • Core protein: A pleiotropic keystone in the HBV lifecycle

    Adam Zlotnick;Balasubramanian Venkatakrishnan;Zhenning Tan;Eric Lewellyn

  • Localization of the C Terminus of the Assembly Domain of Hepatitis B Virus Capsid Protein: Implications for Morphogenesis and Organization of Encapsidated RNA

    A. Zlotnick;N. Cheng;S. J. Stahl;J. F. Conway

  • Are weak protein-protein interactions the general rule in capsid assembly?

    Adam Zlotnick

  • Theoretical aspects of virus capsid assembly.

    Adam Zlotnick

  • The thermodynamics of virus capsid assembly.

    Sarah Katen;Adam Zlotnick;Adam Zlotnick

  • A simple and general method for determining the protein and nucleic acid content of viruses by UV absorbance.

    J. Zachary Porterfield;Adam Zlotnick;Adam Zlotnick

  • BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly.

    Stephen J Stray;Adam Zlotnick

  • Global Structural Changes in Hepatitis B Virus Capsids Induced by the Assembly Effector HAP1

    Christina R. Bourne;M. G. Finn;Adam Zlotnick

  • Trapping of Hepatitis B Virus capsid assembly intermediates by phenylpropenamide assembly accelerators

    Sarah P. Katen;Srinivas Reddy Chirapu;M.G. Finn;Adam Zlotnick

  • Observed Hysteresis of Virus Capsid Disassembly Is Implicit in Kinetic Models of Assembly

    Sushmita Singh;Adam Zlotnick

  • Full-Length Hepatitis B Virus Core Protein Packages Viral and Heterologous RNA with Similarly High Levels of Cooperativity

    J. Zachary Porterfield;J. Zachary Porterfield;Mary Savari Dhason;Daniel D. Loeb;Michael Nassal

  • Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight into Virus Life Cycle

    Christina Bourne;Sejin Lee;Bollu Venkataiah;Angela Lee

Frequent Co-Authors

Stephen C. Jacobson
Stephen C. Jacobson Indiana University
M. G. Finn
M. G. Finn Georgia Institute of Technology
Naiqian Cheng
Naiqian Cheng National Institutes of Health
Stephen J. Stahl
Stephen J. Stahl National Institutes of Health
Paul T. Wingfield
Paul T. Wingfield National Institutes of Health
James F. Conway
James F. Conway University of Pittsburgh
Martin F. Jarrold
Martin F. Jarrold Indiana University
Alasdair C. Steven
Alasdair C. Steven National Institutes of Health
Gijs J. L. Wuite
Gijs J. L. Wuite Vrije Universiteit Amsterdam

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