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Biology and Biochemistry

D-Index
85
Citations
27066
World Ranking
3142
National Ranking
1589

Overview

Paul T. Wingfield is affiliated with the National Institutes of Health in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with subfields including Molecular Biology, Infectious Diseases, Materials Chemistry, Cell Biology, and Immunology.

The scientist's work has addressed multiple topics such as:

  • Bacteriophages and microbial interactions
  • Iron Metabolism and Disorders
  • Enzyme Structure and Function
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Microtubule and mitosis dynamics

Recent publications by Paul T. Wingfield include:

  • Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism, 2022, Structure
  • Determining structures of RNA conformers using AFM and deep neural networks, 2024, Nature
  • Development of an aerosol intervention for COVID-19 disease: Tolerability of soluble ACE2 (APN01) administered via nebulizer, 2022, PLoS ONE
  • Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300, 2021, mBio
  • Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action, 2021, Journal of Biological Chemistry

Coauthors frequently collaborating with Paul T. Wingfield include:

  • Norman R. Watts
  • Alasdair C. Steven
  • Naiqian Cheng
  • Weimin Wu
  • Rick Huang

The scientist has published in several venues multiple times, among them are:

  • OPAL (Open@LaTrobe) (La Trobe University)
  • Structure
  • PLoS ONE
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Activated STING in a Vascular and Pulmonary Syndrome

    Y. Liu;A.A. Jesus;B. Marrero;D. Yang

  • Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1 beta

    Dominique Marion;Paul C. Driscoll;Lewis E. Kay;Paul T. Wingfield

  • A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G.

    A.M Gronenborn;D.R Filpula;N.Z Essig;A Achari

  • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation.

    B Ensoli;L Buonaguro;G Barillari;V Fiorelli

  • Interleukin-35 induces regulatory B cells that suppress autoimmune disease.

    Ren-Xi Wang;Cheng-Rong Yu;Ivy M Dambuza;Rashid M Mahdi

  • TIMP-2 Mediated Inhibition of Angiogenesis: An MMP-Independent Mechanism

    Dong-Wan Seo;Hongmei Li;Liliana Guedez;Paul T. Wingfield

  • Analysis of the backbone dynamics of interleukin-1 beta using two-dimensional inverse detected heteronuclear 15N-1H NMR spectroscopy.

    G M Clore;P C Driscoll;P T Wingfield;A M Gronenborn

  • Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy

    J F Conway;N Cheng;A Zlotnick;P T Wingfield

  • Three‐dimensional solution structure of the 44 kDa ectodomain of SIV gp41

    Michael Caffrey;Mengli Cai;Joshua Kaufman;Stephen J. Stahl

  • The CD4 Determinant for Downregulation by HIV-1 Nef Directly Binds to Nef. Mapping of the Nef Binding Surface by NMR†

    Stephan Grzesiek;Stephen J. Stahl;Paul T. Wingfield;Ad Bax

  • Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding.

    Frederic D. Bushman;Alan Engelman;Ira Palmer;Paul Wingfield

  • Solution NMR of proteins within polyacrylamide gels: diffusional properties and residual alignment by mechanical stress or embedding of oriented purple membranes.

    Hans-Jürgen Sass;Giovanna Musco;Stephen J. Stahl;Paul T. Wingfield

  • The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase.

    S. Grzesiek;A. Bax;G. M. Clore;A. M. Gronenborn

  • Dimorphism of Hepatitis B Virus Capsids Is Strongly Influenced by the C-Terminus of the Capsid Protein

    A Zlotnick;N Cheng;J F Conway;F P Booy

  • Flexibility and function in HIV-1 protease

    Nicholson Lk;Yamazaki T;Torchia Da;Grzesiek S

  • Cloning and expression of a cDNA for human thioredoxin.

    E E Wollman;L d'Auriol;L Rimsky;A Shaw

  • Protein Precipitation Using Ammonium Sulfate

    Paul T. Wingfield

  • Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element.

    Christian Fankhauser;Elisa Izaurralde;Yasuhisa Adachi;Paul Wingfield

  • IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

    Shlomo Z. Ben-Sasson;Alison Hogg;Jane Hu-Li;Paul Wingfield

  • Anisotropic rotational diffusion of perdeuterated HIV protease from 15N NMR relaxation measurements at two magnetic fields

    Nico Tjandra;Paul Wingfield;Stephen Stahl;Ad Bax

Frequent Co-Authors

Stephen J. Stahl
Stephen J. Stahl National Institutes of Health
Alasdair C. Steven
Alasdair C. Steven National Institutes of Health
Angela M. Gronenborn
Angela M. Gronenborn University of Pittsburgh
Naiqian Cheng
Naiqian Cheng National Institutes of Health
G. Marius Clore
G. Marius Clore National Institutes of Health
Ad Bax
Ad Bax National Institutes of Health
James F. Conway
James F. Conway University of Pittsburgh
Dennis A. Torchia
Dennis A. Torchia National Institutes of Health
Stephan Grzesiek
Stephan Grzesiek University of Basel
Adam Zlotnick
Adam Zlotnick Indiana University

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