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Microbiology

D-Index
64
Citations
37054
World Ranking
2559
National Ranking
154

Overview

Patricia Lepage is affiliated with the University of Paris-Saclay in France. Their research spans multiple disciplines within the medical and biological sciences, with a primary focus on medicine and biochemistry, genetics, and molecular biology. Their work integrates molecular biology approaches and covers subfields such as infectious diseases, genetics, gastroenterology, and oncology.

Their research topics cover:

  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Infant nutrition and health
  • Gastrointestinal motility and disorders
  • Tryptophan and brain disorders
  • Cancer immunotherapy and biomarkers
  • Mycobacterium research and diagnosis

Patricia Lepage has frequently published in the following venues:

  • Scientific Reports
  • Journal of Crohn's and Colitis
  • Nature Communications
  • Nature Medicine
  • JAMA Network Open

Notable recent papers include:

  • "Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer," 2020, Nature Communications
  • "Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer," 2020, Nature Medicine
  • "Assessment of Neonatal Intensive Care Unit Practices and Preterm Newborn Gut Microbiota and 2-Year Neurodevelopmental Outcomes," 2020, JAMA Network Open
  • "The gut microbiota posttranslationally modifies IgA1 in autoimmune glomerulonephritis," 2024, Science Translational Medicine
  • "Impact and consequences of intensive chemotherapy on intestinal barrier and microbiota in acute myeloid leukemia: the role of mucosal strengthening," 2020, Gut Microbes

Frequent collaborators in Patricia Lepage's research include:

  • Zehra Esra Ilhan
  • Jean-Christophe Rozé
  • Céline Monot
  • Julio Aires
  • Marie-José Butel

Best Publications

  • A human gut microbial gene catalogue established by metagenomic sequencing

    Junjie Qin;Ruiqiang Li;Jeroen Raes;Manimozhiyan Arumugam

  • Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

    Marie Vétizou;Marie Vétizou;Marie Vétizou;Jonathan M. Pitt;Jonathan M. Pitt;Jonathan M. Pitt;Romain Daillère;Romain Daillère;Romain Daillère;Patricia Lepage

  • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

    Sophie Viaud;Sophie Viaud;Fabiana Saccheri;Grégoire Mignot;Takahiro Yamazaki

  • Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab.

    N. Chaput;P. Lepage;C. Coutzac;C. Coutzac;E. Soularue;E. Soularue

  • Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

    Tiphaine Le Roy;Marta Llopis;Patricia Lepage;Aurélia Bruneau

  • Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors

    Jonathan M. Pitt;Marie Vétizou;Marie Vétizou;Marie Vétizou;Romain Daillère;Romain Daillère;Romain Daillère;María Paula Roberti

  • Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

    Romain Daillère;Romain Daillère;Romain Daillère;Marie Vétizou;Marie Vétizou;Marie Vétizou;Nadine Waldschmitt;Takahiro Yamazaki;Takahiro Yamazaki

  • High-fat diet alters gut microbiota physiology in mice

    Hannelore Daniel;Amin Moghaddas Gholami;David Berry;Charles Desmarchelier

  • Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis.

    Patricia Lepage;Patricia Lepage;Robert Häsler;Martina E. Spehlmann;Ateequr Rehman

  • Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease

    M Llopis;A M Cassard;L Wrzosek;L Boschat

  • Specificities of the fecal microbiota in inflammatory bowel disease

    Harry Sokol;Philippe Seksik;Lionel Rigottier-Gois;Christophe Lay

  • A metagenomic insight into our gut's microbiome

    Patricia Lepage;Patricia Lepage;Marion C Leclerc;Marion C Leclerc;Marie Joossens;Marie Joossens;Stanislas Mondot

  • Early‐life establishment of the swine gut microbiome and impact on host phenotypes

    Núria Mach;Mustapha Berri;Mustapha Berri;Jordi Estellé;Jordi Estellé;Florence Levenez;Florence Levenez

  • Insect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides.

    J Lambert;E Keppi;J L Dimarcq;C Wicker

  • Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer.

    Clélia Coutzac;Jean Mehdi Jouniaux;Jean Mehdi Jouniaux;Angelo Paci;Angelo Paci;Julien Schmidt;Julien Schmidt

  • Resilience of the Dominant Human Fecal Microbiota upon Short-Course Antibiotic Challenge

    M. F. De La Cochetière;T. Durand;P. Lepage;A. Bourreille

  • Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

    J. Amar;M. Serino;C. Lange;C. Chabo

  • Phylogenetic network analysis applied to pig gut microbiota identifies an ecosystem structure linked with growth traits.

    Yuliaxis Ramayo-Caldas;Nuria Mach;Patricia Lepage;Patricia Lepage;Florence Levenez;Florence Levenez

  • Biodiversity of the mucosa‐associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD

    Patricia Lepage;Philippe Seksik;Malène Sutren;Marie-France de la Cochetière

  • Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study

    Martina E. Spehlmann;Alexander Z. Begun;Jens Burghardt;Patricia Lepage

Frequent Co-Authors

Joël Doré
Joël Doré INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Hervé M. Blottière
Hervé M. Blottière University of Paris-Saclay
Sylvie Rabot
Sylvie Rabot University of Paris-Saclay
Nathalie Chaput
Nathalie Chaput Institut Gustave Roussy
Caroline Robert
Caroline Robert University of Paris-Saclay
Harry Sokol
Harry Sokol Sorbonne University
Mathias Chamaillard
Mathias Chamaillard University of Lille
Ivo G. Boneca
Ivo G. Boneca Institut Pasteur
Thomas Clavel
Thomas Clavel RWTH Aachen University
Takahiro Yamazaki
Takahiro Yamazaki Cornell University

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