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Immunology

D-Index
70
Citations
31152
World Ranking
2367
National Ranking
96

Overview

Nathalie Chaput is affiliated with the Institut Gustave Roussy in France. Their research primarily spans the field of Medicine, with a strong focus on Oncology, Pulmonary and Respiratory Medicine, Immunology, Cancer Research, and Molecular Biology. The scientist's body of work includes 158 publications across these domains.

The main topics addressed in their research include:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Renal cell carcinoma treatment
  • Lung Cancer Research Studies
  • Lung Cancer Treatments and Mutations
  • Cancer Genomics and Diagnostics
  • Immune cells in cancer

Several recent papers authored by or involving Nathalie Chaput highlight research in cancer immunotherapy and related clinical insights. Key publications include:

  • "Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer," 2020, Nature Communications
  • "Tocilizumab, an anti-IL-6 receptor antibody, to treat COVID-19-related respiratory failure: a case report," 2020, Annals of Oncology
  • "Tumour burden and efficacy of immune-checkpoint inhibitors," 2021, Nature Reviews Clinical Oncology
  • "Comparative assessment of early mortality risk upon immune checkpoint inhibitors alone or in combination with other agents across solid malignancies: a systematic review and meta-analysis," 2022, European Journal of Cancer
  • "Circulating T-cell Immunosenescence in Patients with Advanced Non-small Cell Lung Cancer Treated with Single-agent PD-1/PD-L1 Inhibitors or Platinum-based Chemotherapy," 2020, Clinical Cancer Research

The scientist frequently publishes in several venues, most notably:

  • Annals of Oncology
  • European Journal of Cancer
  • Journal for ImmunoTherapy of Cancer
  • Journal of Clinical Oncology
  • Clinical Cancer Research

Nathalie Chaput collaborates regularly with other researchers. Frequent co-authors include:

  • Marie Naigeon
  • Benjamin Besse
  • Aurélien Marabelle
  • Lydie Cassard
  • Laurence Albigès

Best Publications

  • Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

    Marie Vétizou;Marie Vétizou;Marie Vétizou;Jonathan M. Pitt;Jonathan M. Pitt;Jonathan M. Pitt;Romain Daillère;Romain Daillère;Romain Daillère;Patricia Lepage

  • Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.

    Noelia Casares;Marie O. Pequignot;Antoine Tesniere;François Ghiringhelli

  • Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

    Bernard Escudier;Thierry Dorval;Nathalie Chaput;Fabrice André

  • Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  • Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab.

    N. Chaput;P. Lepage;C. Coutzac;C. Coutzac;E. Soularue;E. Soularue

  • Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1.

    Stephane Champiat;Stephane Champiat;Laurent Dercle;Samy Ammari;Christophe Massard

  • CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

    Francois Ghiringhelli;Cédric Ménard;Magali Terme;Caroline Flament

  • Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non-Small Cell Lung Cancer.

    Laura Mezquita;Edouard Auclin;Roberto Ferrara;Melinda Charrier

  • Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC

    Benjamin Besse;Mélinda Charrier;Valérie Lapierre;Eric Dansin

  • Exosomes: immune properties and potential clinical implementations

    Nathalie Chaput;Clotilde Théry;Clotilde Théry

  • The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.

    Lionel Apetoh;François Ghiringhelli;Antoine Tesniere;Antoine Tesniere;Antoine Tesniere;Alfredo Criollo;Alfredo Criollo;Alfredo Criollo

  • Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells

    Fabrice André;Nathalie Chaput;Nöel E. C. Schartz;Caroline Flament

  • A novel dendritic cell subset involved in tumor immunosurveillance.

    Julien Taieb;Nathalie Chaput;Cédric Ménard;Lionel Apetoh

  • Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

    Sophie Viaud;Sophie Viaud;Magali Terme;Magali Terme;Caroline Flament;Caroline Flament;Julien Taieb;Julien Taieb

  • Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.

    Yuting Ma;Laetitia Aymeric;Clara Locher;Stephen R Mattarollo

  • Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer.

    Clélia Coutzac;Jean Mehdi Jouniaux;Jean Mehdi Jouniaux;Angelo Paci;Angelo Paci;Julien Schmidt;Julien Schmidt

  • Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway

    Laurence Zitvogel;Oliver Kepp;Laura Senovilla;Laurie Menger

  • IL-18 induces PD-1-dependent immunosuppression in cancer.

    Magali Terme;Evelyn Ullrich;Laetitia Aymeric;Kathrin Meinhardt

  • Experience in daily practice with ipilimumab for the treatment of patients with metastatic melanoma: an early increase in lymphocyte and eosinophil counts is associated with improved survival

    J. Delyon;C. Mateus;D. Lefeuvre;E. Lanoy

  • Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

    Nicolas F. Delahaye;Sylvie Rusakiewicz;Sylvie Rusakiewicz;Isabelle Martins;Cédric Ménard;Cédric Ménard

  • Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?

    Sophie Viaud;Clotilde Théry;Stéphanie Ploix;Thomas Tursz

  • Applying extracellular vesicles based therapeutics in clinical trials

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

Frequent Co-Authors

Laurence Zitvogel
Laurence Zitvogel University of Paris-Saclay
Benjamin Besse
Benjamin Besse University of Paris-Saclay
David Planchard
David Planchard Institut Gustave Roussy
Guido Kroemer
Guido Kroemer Université Paris Cité
Caroline Robert
Caroline Robert University of Paris-Saclay
Fabrice Andre
Fabrice Andre Institut Gustave Roussy
Jean-Charles Soria
Jean-Charles Soria Amgen (United States)
François Ghiringhelli
François Ghiringhelli Centre Georges François Leclerc
Alexander M.M. Eggermont
Alexander M.M. Eggermont Institut Gustave Roussy
Bernard Escudier
Bernard Escudier Institut Gustave Roussy

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