World's Best Scientists 2026 revealed!
Curtis Huttenhower

Curtis Huttenhower

D-Index & Metrics

Biology and Biochemistry

D-Index
144
Citations
178204
World Ranking
225
National Ranking
156

Overview

Curtis Huttenhower is affiliated with Harvard University in the United States. Their research spans multiple areas within the broader fields of biochemistry, genetics, molecular biology, and medicine. Huttenhower's work primarily focuses on molecular biology, physiology, public health, environmental and occupational health, oncology, and ecology.

The scientist has contributed extensively to the study of gut microbiota and health, diet and metabolism studies, nutritional studies and diet, genomics and phylogenetic studies, probiotics and fermented foods, metabolomics and mass spectrometry studies, and colorectal cancer screening and detection.

Among recent notable publications are:

  • PICRUSt2 for prediction of metagenome functions, 2020, Nature Biotechnology
  • Multivariable association discovery in population-scale meta-omics studies, 2021, PLoS Computational Biology
  • Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3, 2021, eLife
  • Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4, 2023, Nature Biotechnology
  • Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals, 2021, Nature Medicine

Huttenhower frequently publishes in several venues, including:

  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Developments in Nutrition
  • Nature Medicine
  • Zenodo (CERN European Organization for Nuclear Research)

Collaboration is a significant aspect of Huttenhower's research, with frequent coauthors including Andrew T. Chan, Eric A. Franzosa, Long H. Nguyen, Mingyang Song, and Wendy S. Garrett. These collaborations span multiple projects and fields, reflecting a broad network in scientific research.

Best Publications

  • Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

    Evan Bolyen;Jai Ram Rideout;Matthew R. Dillon;Nicholas A. Bokulich

  • Metagenomic biomarker discovery and explanation

    Nicola Segata;Jacques Izard;Levi Waldron;Dirk Gevers

  • Structure, function and diversity of the healthy human microbiome

    Curtis Huttenhower;Curtis Huttenhower;Dirk Gevers;Rob Knight;Rob Knight;Sahar Abubucker

  • Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

    Morgan G I Langille;Jesse Zaneveld;J Gregory Caporaso;J Gregory Caporaso;Daniel McDonald

  • Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2.

    Evan Bolyen;Jai Ram Rideout;Matthew R. Dillon;Nicholas A. Bokulich

  • PICRUSt2 for prediction of metagenome functions.

    Gavin M. Douglas;Vincent J. Maffei;Jesse R. Zaneveld;Svetlana N. Yurgel

  • The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

    Dirk Gevers;Subra Kugathasan;Lee A. Denson;Yoshiki Vázquez-Baeza

  • Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

    Xochitl C Morgan;Timothy L Tickle;Timothy L Tickle;Harry Sokol;Harry Sokol;Dirk Gevers

  • Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

    Jason Lloyd-Price;Jason Lloyd-Price;Cesar Arze;Ashwin N. Ananthakrishnan;Melanie Schirmer;Melanie Schirmer

  • A framework for human microbiome research

    Barbara A. Methé;Karen E. Nelson;Mihai Pop;Heather H. Creasy

  • Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

    Aleksandar D. Kostic;Dirk Gevers;Chandra Sekhar Pedamallu;Chandra Sekhar Pedamallu;Monia Michaud

  • Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

    Jose U Scher;Andrew Sczesnak;Andrew Sczesnak;Randy S Longman;Randy S Longman;Nicola Segata;Nicola Segata

  • MetaPhlAn2 for enhanced metagenomic taxonomic profiling.

    Duy Tin Truong;Eric A Franzosa;Timothy L Tickle;Timothy L Tickle;Matthias Scholz

  • Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.

    Alexandra Zhernakova;Alexander Kurilshikov;Marc Jan Bonder;Ettje F. Tigchelaar

  • Temporal development of the gut microbiome in early childhood from the TEDDY study

    Christopher J. Stewart;Christopher J. Stewart;Nadim J. Ajami;Jacqueline L. O’Brien;Diane S. Hutchinson

  • Gut microbiome structure and metabolic activity in inflammatory bowel disease

    Eric A Franzosa;Eric A Franzosa;Alexandra Sirota-Madi;Julian Avila-Pacheco;Nadine Fornelos

  • Metagenomic microbial community profiling using unique clade-specific marker genes.

    Nicola Segata;Levi D. Waldron;Annalisa Ballarini;Vagheesh Narasimhan

  • The healthy human microbiome

    Jason Lloyd-Price;Jason Lloyd-Price;Galeb Abu-Ali;Curtis Huttenhower;Curtis Huttenhower

  • Microbial Co-occurrence Relationships in the Human Microbiome

    Karoline Faust;J. Fah Sathirapongsasuti;Jacques Izard;Jacques Izard;Nicola Segata

  • Multivariable association discovery in population-scale meta-omics studies.

    Himel Mallick;Himel Mallick;Ali Rahnavard;Lauren J. McIver;Lauren J. McIver;Siyuan Ma;Siyuan Ma

Frequent Co-Authors

Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Eric A. Franzosa
Eric A. Franzosa Harvard University
Nicola Segata
Nicola Segata University of Trento
Wendy S. Garrett
Wendy S. Garrett Harvard University
Andrew T. Chan
Andrew T. Chan Harvard University
Dirk Gevers
Dirk Gevers Johnson & Johnson (United States)
Rob Knight
Rob Knight University of California, San Diego
Hera Vlamakis
Hera Vlamakis Broad Institute
Shuji Ogino
Shuji Ogino Brigham and Women's Hospital

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