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Neuroscience

D-Index
52
Citations
12956
World Ranking
5239
National Ranking
2344

Overview

Smriti Iyengar is affiliated with Eli Lilly in the United States and has contributed extensively to the field of medicine with a strong focus on pain research. Their work spans several subfields, including physiology, anesthesiology and pain medicine, public health, environmental and occupational health, pharmacology, and economics and econometrics.

Their research interests primarily cover topics related to pain mechanisms and treatments, pain management and opioid use, health systems, economic evaluations and quality of life, musculoskeletal pain and rehabilitation, placebo effects in pain management, animal testing and alternatives, and opioid use disorder treatment.

Frequent publication venues for Iyengar include:

  • Pain
  • Journal of Pain
  • Neurotherapeutics
  • Nature Reviews Neurology
  • EClinicalMedicine

Among their recent publications are:

  • "Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities," 2020, Nature Reviews Neurology
  • "Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations," 2020, Pain
  • "Developing consensus on core outcome sets of domains for acute, the transition from acute to chronic, recurrent/episodic, and chronic pain: results of the INTEGRATE-pain Delphi process," 2023, EClinicalMedicine
  • "Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations," 2021, PAIN Reports
  • "Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement," 2023, Pain

Co-authors frequently collaborating with Iyengar include:

  • Sarah A. Woller
  • Dennis C. Turk
  • Robert H. Dworkin
  • John T. Farrar
  • Penney Cowan

Smriti Iyengar's research consolidates multidisciplinary approaches to understanding and managing pain through both clinical and public health perspectives. Their work contributes to improving methodologies for pain assessment and treatment, including developing core outcome sets and research design recommendations for clinical trials in pain therapeutics.

Best Publications

  • Duloxetine vs. placebo in patients with painful diabetic neuropathy.

    David J. Goldstein;Yili Lu;Michael J. Detke;Michael J. Detke;Thomas C. Lee

  • A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.

    Lesley M. Arnold;Yili Lu;Leslie J. Crofford;Madelaine Wohlreich

  • A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain.

    Joel Raskin;Yili L. Pritchett;Fujun Wang;Deborah N. D'Souza

  • A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder.

    Lesley M. Arnold;Amy Rosen;Yili Lu Pritchett;Deborah N. D'Souza

  • A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain

    J. F. Wernicke;Y. L. Pritchett;D. N. D’Souza;A. Waninger

  • The role of calcitonin gene-related peptide in peripheral and central pain mechanisms including migraine.

    Smriti Iyengar;Michael H. Ossipov;Kirk W. Johnson

  • CGRP and the Trigeminal System in Migraine.

    Smriti Iyengar;Kirk W. Johnson;Michael H. Ossipov;Sheena K. Aurora

  • Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities.

    Karen D. Davis;Karen D. Davis;Nima Aghaeepour;Andrew H. Ahn;Martin S. Angst

  • Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats

    Smriti Iyengar;Amy A Webster;Susan K Hemrick-Luecke;Jimmy Yu Xu

  • Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial.

    Amy S. Chappell;Melissa J. Ossanna;Hong Liu-Seifert;Smriti Iyengar

  • Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations

    Dennis C. Turk;Robert H. Dworkin;Michael P. McDermott;Nicholas Bellamy

  • Efficacy and safety of duloxetine in patients with chronic low back pain.

    Vladimir Skljarevski;Durisala Desaiah;Hong Liu-Seifert;Qi Zhang

  • Depression and pain.

    Michael J. Robinson;Sara E. Edwards;Smriti Iyengar;Frank Bymaster

  • Inhibition of Nitric Oxide Synthase Blocks N‐Methyl‐D‐Aspartate‐, Quisqualate‐, Kainate‐, Harmaline‐, and Pentylenetetrazole‐Dependent Increases in Cerebellar Cyclic GMP In Vivo

    Paul L. Wood;Mark R. Emmett;Tadimeti S. Rao;Julie Cler

  • Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat.

    Rosa Maria A. Simmons;Dominic L. Li;Ken H. Hoo;Michelle Deverill

  • Effects of Duloxetine on Painful Physical Symptoms Associated With Depression

    David J. Goldstein;Yili Lu;Michael J. Detke;James Hudson

  • Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats.

    Rosa Maria A. Simmons;Amy A. Webster;Anshu B. Kalra;Smriti Iyengar

  • The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression.

    Frank P. Bymaster;Thomas C. Lee;Mary Pat Knadler;Michael J. Detke

  • Duloxetine for the Management of Diabetic Peripheral Neuropathic Pain: Evidence-Based Findings from Post Hoc Analysis of Three Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Studies

    Daniel K. Kajdasz;Smriti Iyengar;Durisala Desaiah;Misha Miroslav Backonja

  • Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials.

    Lesley M. Arnold;Yili Lu Pritchett;Deborah N. D'Souza;Daniel K. Kajdasz

  • Review and recommendations Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations

    Dennis C. Turk;Robert H. Dworkin;Michael P. McDermott;Nicholas Bellamy

Frequent Co-Authors

Lino Becerra
Lino Becerra Harvard Medical School
David Borsook
David Borsook Boston Children's Hospital
Richard Hargreaves
Richard Hargreaves Harvard Medical School
Mark P. Jensen
Mark P. Jensen University of Washington
Clifford J. Woolf
Clifford J. Woolf Boston Children's Hospital
Anne Louise Oaklander
Anne Louise Oaklander Harvard University
Christopher Eccleston
Christopher Eccleston University of Bath

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