World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13496
World Ranking
10819
National Ranking
737

Overview

Shizuo Yamada is affiliated with the University of Shizuoka in Japan and has contributed to research primarily in the field of medicine. Their work spans multiple biomedical disciplines, including molecular biology, physiology, urology, neurology, and biochemistry.

Their recent publications demonstrate involvement in diverse pharmacological and biomedical topics. Notable papers include:

  • Beneficial effects of a nobiletin-rich formulated supplement of Sikwasa (C. depressa) peel on cognitive function in elderly Japanese subjects; A multicenter, randomized, double-blind, placebo-controlled study, 2021, published in Food Science & Nutrition
  • Development of a pharmacological evidence-based anticholinergic burden scale for medications commonly used in older adults, 2023, published in Geriatrics and gerontology international/Geriatrics & gerontology international

They have also coauthored papers with other researchers such as Kazumasa Shinozuka, Satomi Kagota, Yoshihisa Kato, Junko Chimoto, and Yutaka Nakagawa, suggesting collaboration in overlapping research areas.

Their major publication venues reflect a focus on geriatric pharmacology and therapeutic sciences, including:

  • Geriatrics and gerontology international/Geriatrics & gerontology international
  • Journal of Pharmacology and Experimental Therapeutics
  • European Journal of Pharmacology
  • Nutrients
  • Journal of Pharmacological Sciences

They have frequently explored topics connected to urinary bladder and prostate research, receptor mechanisms and signaling, circadian rhythm and melatonin, pharmaceutical practices and patient outcomes, analytical methods in pharmaceuticals, urinary tract infections management, and phytochemicals and antioxidant activities.

These thematic areas underscore a research focus on pharmacological interventions, biochemical pathways, and clinical outcomes relevant to aging populations and neurological health.

Best Publications

  • Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications.

    Yohei Kawabata;Koichi Wada;Manabu Nakatani;Shizuo Yamada

  • Nanodrugs: pharmacokinetics and safety

    Satomi Onoue;Shizuo Yamada;Hak-Kim Chan

  • Formulation design and photochemical studies on nanocrystal solid dispersion of curcumin with improved oral bioavailability.

    Satomi Onoue;Haruki Takahashi;Yohei Kawabata;Yoshiki Seto

  • Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy.

    S Yamada;N Ashizawa;H Ushijima;K Nakayama

  • Physicochemical and pharmacological characterization of α-tocopherol-loaded nano-emulsion system.

    Junya Hatanaka;Hina Chikamori;Hideyuki Sato;Shinya Uchida

  • Green tea ingestion greatly reduces plasma concentrations of nadolol in healthy subjects.

    S Misaka;S Misaka;J Yatabe;F Müller;K Takano

  • Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers.

    Shinya Uchida;Hiroshi Yamada;Xiao Dong Li;Shuji Maruyama

  • High affinity renal [3H]flunitrazepam binding: Characterization, localization, and alteration in hypertension

    John W. Regan;Henry I. Yamamura;Shizuo Yamada;William R. Roeske

  • Involvement of dopamine receptors in the anti-immobility effects of dopamine re-uptake inhibitors in the forced swimming test.

    Jun Yamada;Yumi Sugimoto;Shizuo Yamada

  • Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors

    Kazufumi Hirano;Ryohei Kimura;Yumi Sugimoto;Jun Yamada

  • Effects of purine compounds on cholinergic nerves. Specificity of adenosine and related compounds on acetylcholine release in electrically stimulated guinea pig ileum

    Eiichi Hayashi;Motokuni Mori;Shizuo Yamada;Masaru Kunitomo

  • Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes

    Shingen Misaka;Keisuke Kawabe;Satomi Onoue;José Pablo Werba

  • Physicochemical and pharmacokinetic characterization of water-soluble Coenzyme Q10 formulations

    Junya Hatanaka;Yoshihiro Kimura;Zhogn Lai-Fu;Satomi Onoue

  • Regional adaptation of muscarinic receptors and choline uptake in brain following repeated administration of diisopropylfluorophosphate and atropine.

    Shizuo Yamada;Mitsutaka Isogai;Hiromi Okudaira;Eiichi Hayashi

  • Novel solid self-emulsifying drug delivery system of coenzyme Q₁₀ with improved photochemical and pharmacokinetic behaviors.

    Satomi Onoue;Atushi Uchida;Kazuki Kuriyama;Tatsuya Nakamura

  • Correlation between cholinesterase inhibition and reduction in muscarinic receptors and choline uptake by repeated diisopropylfluorophosphate administration: antagonism by physostigmine and atropine.

    S Yamada;M Isogai;H Okudaira;E Hayashi

  • A Possible Mechanism for Decrease in Serum Thyroxine Level by Polychlorinated Biphenyls in Wistar and Gunn Rats

    Yoshihisa Kato;Shinichi Ikushiro;Koichi Haraguchi;Tomoaki Yamazaki

  • Study on brain interstitial fluid distribution and blood-brain barrier transport of baclofen in rats by microdialysis.

    Yoshiharu Deguchi;Kazimori Inabe;Koichi Tomiyasu;Kenji Nozawa

  • Quantitative analysis of binding parameters of [3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice.

    Tomomi Oki;Yukiko Takagi;Sayuri Inagaki;Makoto M. Taketo

  • Functional analysis of muscarinic acetylcholine receptors using knockout mice

    Minoru Matsui;Shizuo Yamada;Tomomi Oki;Toshiya Manabe

Frequent Co-Authors

Satoshi Shuto
Satoshi Shuto Hokkaido University
Hideo Tsukada
Hideo Tsukada Hamamatsu Photonics (Japan)
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
Henry I. Yamamura
Henry I. Yamamura University of Arizona
Naoto Oku
Naoto Oku University of Shizuoka
William M. Pardridge
William M. Pardridge University of California, Los Angeles
Hiroshi Watanabe
Hiroshi Watanabe Niigata University
Shingo Nishiyama
Shingo Nishiyama Hamamatsu Photonics (Japan)
Tetsuya Terasaki
Tetsuya Terasaki Tohoku University

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