2014 - Fellow, National Academy of Inventors
His main research concerns Immunology, Cytotoxic T cell, Virology, CD8 and Antigen. His work in T cell, Immune system, Viral load, Viral disease and Cellular immunity are all subfields of Immunology research. His Cytotoxic T cell research is multidisciplinary, relying on both T lymphocyte and Effector.
His research in Virology intersects with topics in Epitope and Orthopoxvirus. His work investigates the relationship between Antigen and topics such as Flow cytometry that intersect with problems in Cytokine, Fusion protein, Receptor, Transfection and Cell culture. His Interleukin 21 research incorporates themes from Natural killer T cell, Natural killer cell, Interleukin 12 and IL-2 receptor.
Douglas F. Nixon mainly investigates Immunology, Virology, Immune system, Cytotoxic T cell and T cell. Immunology is a component of his CD8, Viral load, Antigen, Interleukin 21 and Natural killer T cell studies. His Interleukin 21 research includes elements of Interleukin 12 and Cell biology.
Douglas F. Nixon has researched Virology in several fields, including Epitope, ELISPOT, T lymphocyte and CTL*. He focuses mostly in the field of Immune system, narrowing it down to matters related to Human leukocyte antigen and, in some cases, Allele. The study incorporates disciplines such as Major histocompatibility complex, Simian immunodeficiency virus and Effector in addition to Cytotoxic T cell.
The scientist’s investigation covers issues in Virology, Immunology, Virus, Cell biology and Immune system. His Virology research is multidisciplinary, incorporating elements of Epitope, Cd4 t cell and Severe acute respiratory syndrome coronavirus 2. His Immunology study frequently draws connections to other fields, such as Gene expression.
His study in Virus is interdisciplinary in nature, drawing from both SNP, Fetus and Downregulation and upregulation, Gene. The concepts of his Immune system study are interwoven with issues in Cancer research, Transcription and Breast cancer. As a part of the same scientific study, he usually deals with the Effector, concentrating on Virus latency and frequently concerns with Cytotoxic T cell.
His scientific interests lie mostly in Virology, Cell biology, Virus, CD8 and Zika virus. His Virology research includes themes of Epidemiology, Immune system and Severe acute respiratory syndrome coronavirus 2. His Immune system study combines topics in areas such as Virus latency, Human endogenous retrovirus K, Endogenous retrovirus and Epigenetics.
His Cell biology study deals with Receptor intersecting with T cell, RAR-related orphan receptor gamma, NKG2D, MHC class I and T-cell receptor. The various areas that Douglas F. Nixon examines in his Virus study include Disease reservoir, Viral quasispecies, Human leukocyte antigen, Genotype and CTL*. His studies deal with areas such as Cell, Mucosal associated invariant T cell, Virus Activation, Epitope and Effector as well as CD8.
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Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.
G. S. Ogg;Xia Jin;S. Bonhoeffer;P. R. Dunbar.
Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition.
R E Phillips;S Rowland-Jones;D F Nixon;F M Gotch.
HIV-Specific Cd8+T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function
Victor Appay;Douglas F. Nixon;Sean M. Donahoe;Geraldine M.A. Gillespie.
Journal of Experimental Medicine (2000)
Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero
Jeff E. Mold;Jakob Michaëlsson;Trevor D. Burt;Marcus O. Muench.
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
R. Brad Jones;Lishomwa C Ndhlovu;Jason D. Barbour;Prameet M. Sheth.
Journal of Experimental Medicine (2008)
Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection
Sandra Lopez-Vergès;Jeffrey M. Milush;Brian S. Schwartz;Marcelo J. Pando.
Proceedings of the National Academy of Sciences of the United States of America (2011)
CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset
Sandra Lopez-Vergès;Jeffrey M. Milush;Suchitra Pandey;Vanessa A. York.
Human CD4+ CD25+ Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens
Einar M. Aandahl;Jakob Michaëlsson;Walter J. Moretto;Frederick M. Hecht.
Journal of Virology (2004)
HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides
Douglas F. Nixon;Alain R. M. Townsend;John G. Elvin;Charles R. Rizza.
An Effective AIDS Vaccine Based on Live Attenuated Vesicular Stomatitis Virus Recombinants
Nina F. Rose;Preston A. Marx;Preston A. Marx;Amara Luckay;Douglas F. Nixon.
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