His scientific interests lie mostly in Immunology, Immune system, Immunotherapy, Antigen and Virology. The study incorporates disciplines such as Epitope, Antibody, Dosage form and Vaccination in addition to Immune system. The Virology study combines topics in areas such as Acquired immune system and Tolerance induction.
He interconnects Cyclophosphamide, B cell, Adoptive cell transfer, Follicular lymphoma and Polyclonal B cell response in the investigation of issues within Chimeric antigen receptor. His Follicular lymphoma research integrates issues from Survival rate, Cancer research, Oncology and Primary mediastinal B-cell lymphoma. His research in Refractory Diffuse Large B-Cell Lymphoma intersects with topics in B-cell lymphoma, Chimeric Antigen Receptor T-Cell Therapy and Fludarabine.
Immunology, Immune system, Antigen, Cancer research and T cell are his primary areas of study. Adrian Bot works mostly in the field of Immunology, limiting it down to topics relating to Internal medicine and, in certain cases, Gastroenterology, as a part of the same area of interest. His biological study spans a wide range of topics, including Epitope, Cancer and Virus, Virology.
His Antigen study combines topics in areas such as Antigen-presenting cell, Autoimmunity and Cell biology. His Cancer research research is multidisciplinary, incorporating elements of B-cell lymphoma, Anti cd19 and CD19. His T cell study combines topics from a wide range of disciplines, such as Molecular biology, CD8 and B cell.
His primary areas of investigation include Cancer research, Internal medicine, T cell, Chimeric antigen receptor and B-cell lymphoma. His Cancer research research incorporates elements of Anti cd19, Immune system and Antigen. His Internal medicine study frequently involves adjacent topics like Oncology.
His study on Chimeric antigen receptor is covered under Immunology. His B-cell lymphoma research focuses on Refractory and how it relates to CAR T-cell therapy and Long term survival. He has included themes like Cyclophosphamide and Chimeric Antigen Receptor T-Cell Therapy in his Lymphoma study.
Adrian Bot mainly focuses on Chimeric antigen receptor, Lymphoma, Internal medicine, B-cell lymphoma and Cancer research. His research investigates the connection between Chimeric antigen receptor and topics such as Antigen that intersect with problems in Adoptive cell transfer. His work on Fludarabine, Refractory Diffuse Large B-Cell Lymphoma and Refractory as part of general Internal medicine research is frequently linked to Multicenter trial, bridging the gap between disciplines.
His work in Fludarabine addresses subjects such as Chimeric Antigen Receptor T-Cell Therapy, which are connected to disciplines such as Polyclonal B cell response and Survival rate. The Cancer research study which covers CD19 that intersects with Acute lymphocytic leukemia, K562 cells, Rituximab, Lineage and Toxicity. The study of Immunology is intertwined with the study of Cyclophosphamide in a number of ways.
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Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
Sattva S. Neelapu;Frederick L. Locke;Nancy L. Bartlett;Lazaros J. Lekakis.
The New England Journal of Medicine (2017)
Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial
Frederick L Locke;Armin Ghobadi;Caron A Jacobson;David B Miklos.
Lancet Oncology (2019)
Phase 1 Results of ZUMA-1: A Multicenter Study of KTE-C19 Anti-CD19 CAR T Cell Therapy in Refractory Aggressive Lymphoma
Frederick L. Locke;Sattva S. Neelapu;Nancy L. Bartlett;Tanya Siddiqi.
Molecular Therapy (2017)
Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels
James N. Kochenderfer;Robert P.T. Somerville;Tangying Lu;Victoria Shi.
Journal of Clinical Oncology (2017)
Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy.
James N. Kochenderfer;Robert P.T. Somerville;Tangying Lu;James C. Yang.
Molecular Therapy (2017)
Autoreactive CD4+ T Cells Protect from Autoimmune Diabetes via Bystander Suppression Using the IL-4/Stat6 Pathway
Dirk Homann;Andreas Holz;Adrian Bot;Bryan Coon.
Immunity (1999)
Antigen kinetics determines immune reactivity.
Pål Johansen;Tazio Storni;Lorna Rettig;Zhiyong Qiu.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Protective Role of Gamma Interferon during the Recall Response to Influenza Virus
Adrian Bot;Simona Bot;Constantin A. Bona.
Journal of Virology (1998)
Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells are associated with clinical outcomes in NHL.
John Rossi;Patrick Paczkowski;Yueh-Wei Shen;Kevin Morse.
Blood (2018)
Plasmid Vaccination with Insulin B Chain Prevents Autoimmune Diabetes in Nonobese Diabetic Mice
Adrian Bot;Dan Smith;Simona Bot;Anna Hughes.
Journal of Immunology (2001)
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