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Biology and Biochemistry

D-Index
57
Citations
17750
World Ranking
13573
National Ranking
5755

Overview

Suresh K. Joseph is affiliated with Thomas Jefferson University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant number of publications in molecular biology, genetics, physiology, cellular and molecular neuroscience, and cell biology. The main topics covered in their work include mitochondrial function and pathology, ATP synthase and ATPases research, protein kinase regulation and GTPase signaling, calcium signaling and nucleotide metabolism, connective tissue disorders research, signaling pathways in disease, and metabolism and genetic disorders.

Their notable recent publications include:

  • Oxidative bursts of single mitochondria mediate retrograde signaling toward the ER, 2021, Molecular Cell
  • MICU1 regulates mitochondrial cristae structure and function independently of the mitochondrial Ca 2+ uniporter channel, 2023, Science Signaling
  • Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors, 2022, Proceedings of the National Academy of Sciences
  • Metabolic adaptation to the chronic loss of Ca2+ signaling induced by KO of IP3 receptors or the mitochondrial Ca2+ uniporter, 2021, Journal of Biological Chemistry
  • MICU1 controls the sensitivity of the mitochondrial Ca2+ uniporter to activators and inhibitors, 2023, Cell chemical biology

Their frequent co-authors include György Hajnóczky, David M. Booth, Péter Várnai, Michael Young, and Dhanendra Tomar.

Publication venues for their research have included bioRxiv (Cold Spring Harbor Laboratory), Molecular Cell, Science Signaling, Proceedings of the National Academy of Sciences, and Journal of Biological Chemistry.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

    S K Joseph;A P Thomas;R J Williams;R F Irvine

  • Molecular properties of inositol 1,4,5-trisphosphate receptors

    S. Patel;S.K. Joseph;A.P. Thomas

  • Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver.

    J. R. Williamson;R. H. Cooper;S. K. Joseph;A. P. Thomas

  • S-glutathionylation activates STIM1 and alters mitochondrial homeostasis

    Brian J. Hawkins;Krishna M. Irrinki;Karthik Mallilankaraman;Yu Chin Lien

  • IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer.

    Adam Bartok;Adam Bartok;David Weaver;Tünde Golenár;Zuzana Nichtova

  • IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond

    Suresh K. Joseph;György Hajnóczky

  • Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity

    Zhiwei Dong;Santhanam Shanmughapriya;Dhanendra Tomar;Naveed Siddiqui

  • Determination of the matrix free Ca2+ concentration and kinetics of Ca2+ efflux in liver and heart mitochondria.

    K E Coll;S K Joseph;B E Corkey;J R Williamson

  • The inositol triphosphate receptor family.

    Suresh K. Joseph

  • Detergent solubility of the inositol trisphosphate receptor in rat brain membranes : evidence for association of the receptor with ankyrin

    S. K. Joseph;Saswati Samanta

  • Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.

    Suresh K. Joseph;Chi Lin;Shawn Pierson;Andrew P. Thomas

  • Akt Kinase Phosphorylation of Inositol 1,4,5-Trisphosphate Receptors *

    M. Tariq Khan;Larry Wagner;David I. Yule;Cunnigaiper Bhanumathy

  • Mechanisms underlying calcium homeostasis in isolated hepatocytes.

    S K Joseph;K E Coll;R H Cooper;J S Marks

  • Selective role for superoxide in InsP3 receptor–mediated mitochondrial dysfunction and endothelial apoptosis

    Muniswamy Madesh;Brian J. Hawkins;Tatyana Milovanova;Cunnigaiper D. Bhanumathy

  • Isoform- and Species-specific Control of Inositol 1,4,5-Trisphosphate (IP3) Receptors by Reactive Oxygen Species

    Száva Bánsághi;Tünde Golenár;Muniswamy Madesh;György Csordás

  • The role of extracellular Ca2+ in the response of the hepatocyte to Ca2+-dependent hormones.

    S K Joseph;K E Coll;A P Thomas;R Rubin

  • Hypoxia inducible factor 1α regulates T cell receptor signal transduction

    Aaron K. Neumann;Jaeseok Yang;Mangat P. Biju;Suresh K. Joseph

  • Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors.

    Darren Boehning;Suresh K. Joseph

  • Phosphorylation of the inositol trisphosphate receptor in isolated rat hepatocytes.

    S K Joseph;S V Ryan

Frequent Co-Authors

György Hajnóczky
György Hajnóczky Thomas Jefferson University
David I. Yule
David I. Yule University of Rochester
Andrew P. Thomas
Andrew P. Thomas Rutgers, The State University of New Jersey
Kumar Sharma
Kumar Sharma The University of Texas Health Science Center at San Antonio
John R. Williamson
John R. Williamson University of Pennsylvania
Muniswamy Madesh
Muniswamy Madesh The University of Texas at Austin
Toren Finkel
Toren Finkel University of Pittsburgh
Shey-Shing Sheu
Shey-Shing Sheu Thomas Jefferson University
J. Kevin Foskett
J. Kevin Foskett University of Pennsylvania
Enza Maria Valente
Enza Maria Valente University of Pavia

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