World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
17254
World Ranking
7017
National Ranking
3229

Overview

Andrew P. Thomas is affiliated with Rutgers, The State University of New Jersey in the United States. Their research spans multiple fields with a primary focus on biochemistry, genetics, and molecular biology, complemented by contributions in computer science and medicine.

Their work is concentrated in several specialized subfields including molecular biology, computational theory and mathematics, pathology and forensic medicine, biophysics, and radiology, nuclear medicine, and imaging. This interdisciplinary approach supports research topics such as computational drug discovery methods, melanoma and MAPK pathways, cancer mechanisms and therapy, viral infectious diseases and gene expression in insects, cell image analysis techniques, protein kinase regulation and GTPase signaling, and chemical synthesis and analysis.

Andrew P. Thomas has published research in a variety of scientific journals. Notable recent papers include:

  • "Selective CRAF Inhibition Elicits Transactivation," 2021, Journal of the American Chemical Society
  • "High throughput screening of 0.5 million compounds against CRAF using Alpha CETSA," 2023, SLAS DISCOVERY
  • "Targeting a Novel KRAS Binding Site: Application of One-Component Stapling of Small (5-6-mer) Peptides," 2021, Journal of Medicinal Chemistry

Frequently published venues for their work are:

  • Journal of the American Chemical Society
  • SLAS DISCOVERY
  • Journal of Medicinal Chemistry

Collaboration is an element of Andrew P. Thomas's research profile, with regular coauthors including C. Morgan, Ian L. Dale, James Hunt, Jason W. Chin, and Hannah Rowlands.

Best Publications

  • Decoding of cytosolic calcium oscillations in the mitochondria

    György Hajnóczky;Lawrence D Robb-Gaspers;Michele B Seitz;Andrew P Thomas

  • myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

    S K Joseph;A P Thomas;R J Williams;R F Irvine

  • Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria.

    György Csordás;Andrew P. Thomas;György Hajnóczky

  • SPATIAL AND TEMPORAL ASPECTS OF CELLULAR CALCIUM SIGNALING

    Andrew P. Thomas;Gary St. J. Bird;György Hajnóczky;Lawrence D. Robb-Gaspers

  • Molecular properties of inositol 1,4,5-trisphosphate receptors

    S. Patel;S.K. Joseph;A.P. Thomas

  • Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver.

    J. R. Williamson;R. H. Cooper;S. K. Joseph;A. P. Thomas

  • INTEGRATING CYTOSOLIC CALCIUM SIGNALS INTO MITOCHONDRIAL METABOLIC RESPONSES

    Lawrence D. Robb‐Gaspers;Paul Burnett;Guy A. Rutter;Richard M. Denton

  • Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes.

    T. A. Rooney;E. J. Sass;Andrew Thomas

  • Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34

    Pawan Gulati;Lawrence D. Gaspers;Stephen G. Dann;Manel Joaquin

  • Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

    Andrew Thomas;J. Alexander;J. R. Williamson

  • Coordination of Ca2+ Signaling by Intercellular Propagation of Ca2+ Waves in the Intact Liver (∗)

    Lawrence D. Robb-Gaspers;Andrew P. Thomas

  • Mitochondria Suppress Local Feedback Activation of Inositol 1,4,5-Trisphosphate Receptors by Ca2+

    György Hajnóczky;Richard Hager;Andrew P. Thomas;Andrew P. Thomas

  • Calcium signal transmission between ryanodine receptors and mitochondria.

    Gábor Szalai;György Csordás;Basil M. Hantash;Andrew P. Thomas

  • Agonist-induced cytosolic calcium oscillations originate from a specific locus in single hepatocytes.

    T A Rooney;E J Sass;A P Thomas

  • Direct access to serum macromolecules by intraerythrocytic malaria parasites

    B. Pouvelle;R. Spiegel;L. Hsiao;R. J. Howard

  • Quantitation and early kinetics of inositol lipid changes induced by vasopressin in isolated and cultured hepatocytes

    A P Thomas;J S Marks;K E Coll;J R Williamson

  • Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.

    Takashi Tsuboi;Gabriela da Silva Xavier;George G. Holz;Laurence S. Jouaville

  • Ethanol and signal transduction in the liver.

    Jan B. Hoek;Andrew P. Thomas;Thomas A. Rooney;Katsuyoshi Higashi

  • Ethanol-induced mobilization of calcium by activation of phosphoinositide-specific phospholipase C in intact hepatocytes.

    J. B. Hoek;Andrew Thomas;R. Rubin;E. Rubin

  • Minimal requirements for calcium oscillations driven by the IP3 receptor

    György Hajnóczky;Andrew P. Thomas

Frequent Co-Authors

György Hajnóczky
György Hajnóczky Thomas Jefferson University
John R. Williamson
John R. Williamson University of Pennsylvania
Jan B. Hoek
Jan B. Hoek Thomas Jefferson University
Richard M. Denton
Richard M. Denton University of Bristol
Sandip Patel
Sandip Patel University College London
Suresh K. Joseph
Suresh K. Joseph Thomas Jefferson University
Guy A. Rutter
Guy A. Rutter Imperial College London
Andrew P. Halestrap
Andrew P. Halestrap University of Bristol
John L. Farber
John L. Farber Thomas Jefferson University
James R. Connor
James R. Connor Pennsylvania State University

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