World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
18954
World Ranking
6613
National Ranking
3080

Jan B. Hoek publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jan B. Hoek sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 253 publications — 68th percentile

68% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jan B. Hoek D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jan B. Hoek sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 71 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Jan B. Hoek is affiliated with Thomas Jefferson University in the United States and has made contributions primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research spans several subfields, including Epidemiology, Hepatology, Molecular Biology, Surgery, and Pathology and Forensic Medicine.

Their work covers a range of main topics such as Liver Disease Diagnosis and Treatment, Liver Physiology and Pathology, Mitochondrial Function and Pathology, Liver Disease and Transplantation, Alcohol Consumption and Health Effects, Hepatocellular Carcinoma Treatment and Prognosis, and Autophagy in Disease and Therapy.

Jan B. Hoek has published in various scientific venues with multiple articles in The FASEB Journal being the most frequent, alongside publications in Frontiers in Physiology, Cells, Archives of Toxicology, and Nature Communications.

  • The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity (2021, Cells)
  • Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease (2020, Archives of Toxicology)
  • Computational Modeling Analysis of Generation of Reactive Oxygen Species by Mitochondrial Assembled and Disintegrated Complex II (2020, Frontiers in Physiology)
  • Ethanol Disrupts Hormone-Induced Calcium Signaling in Liver (2021, Function)
  • Dysregulation of miR-21-associated miRNA regulatory networks by chronic ethanol consumption impairs liver regeneration (2021, Physiological Genomics)

Frequent co-authors contributing to joint research with Jan B. Hoek include Rajanikanth Vadigepalli, Alexandra Manchel, Benjamin Barnhart, Ankita Srivastava, and Ramón Bataller.

Best Publications

  • Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

    Nick I. Markevich;Jan B. Hoek;Boris N. Kholodenko

  • Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

    Boris N. Kholodenko;Oleg V. Demin;Gisela Moehren;Jan B. Hoek

  • Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis

    John G. Pastorino;Nataly Shulga;Jan B. Hoek

  • Ethanol, oxidative stress, and cytokine-induced liver cell injury

    Jan B. Hoek;John G. Pastorino

  • Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion.

    Kenneth D. Chavin;ShiQi Yang;Hui Zhi Lin;John Chatham

  • Alcohol and mitochondria: a dysfunctional relationship.

    Jan B. Hoek;Alan Cahill;John G. Pastorino

  • Activation of Glycogen Synthase Kinase 3β Disrupts the Binding of Hexokinase II to Mitochondria by Phosphorylating Voltage-Dependent Anion Channel and Potentiates Chemotherapy-Induced Cytotoxicity

    John G. Pastorino;Jan B. Hoek;Nataly Shulga

  • Untangling the wires: A strategy to trace functional interactions in signaling and gene networks

    Boris N. Kholodenko;Anatoly Kiyatkin;Frank J. Bruggeman;Eduardo Sontag

  • Role of calcium in the hormonal regulation of liver metabolism

    John R. Williamson;Ronald H. Cooper;Jan B. Hoek

  • Regulation of hexokinase binding to VDAC.

    John G. Pastorino;Jan B. Hoek

  • Physiological roles of nicotinamide nucleotide transhydrogenase.

    J B Hoek;J Rydström

  • Functional Consequences of the Sustained or Transient Activation by Bax of the Mitochondrial Permeability Transition Pore

    John G. Pastorino;Marco Tafani;Ronald J. Rothman;Ausra Marcineviciute

  • Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition.

    J G Pastorino;J W Snyder;A Serroni;J B Hoek

  • Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses

    Marc R Birtwistle;Marc R Birtwistle;Mariko Hatakeyama;Noriko Yumoto;Babatunde A Ogunnaike

  • Determination of the mitochondrial protonmotive force in isolated hepatocytes.

    Jan B. Hoek;David G. Nicholls;John R. Williamson

  • Hexokinase II: the integration of energy metabolism and control of apoptosis.

    John G Pastorino;Jan B Hoek

  • Why cytoplasmic signalling proteins should be recruited to cell membranes

    Boris N. Kholodenko;Jan B. Hoek;Hans V. Westerhoff

  • Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling

    Nikolay Borisov;Edita Aksamitiene;Anatoly Kiyatkin;Stefan Legewie

  • Ethanol and signal transduction in the liver.

    Jan B. Hoek;Andrew P. Thomas;Thomas A. Rooney;Katsuyoshi Higashi

  • Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.

    Anatoly Kiyatkin;Edita Aksamitiene;Nick I. Markevich;Nikolay M. Borisov

Frequent Co-Authors

Boris N. Kholodenko
Boris N. Kholodenko University College Dublin
Andrew P. Thomas
Andrew P. Thomas Rutgers, The State University of New Jersey
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Babatunde A. Ogunnaike
Babatunde A. Ogunnaike University of Delaware
György Hajnóczky
György Hajnóczky Thomas Jefferson University
James S. Schwaber
James S. Schwaber Thomas Jefferson University
Rocky S. Tuan
Rocky S. Tuan Chinese University of Hong Kong
Guy C. Brown
Guy C. Brown University of Cambridge
John L. Farber
John L. Farber Thomas Jefferson University
John R. Williamson
John R. Williamson University of Pennsylvania

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