What is he best known for?
The fields of study he is best known for:
- Internal medicine
- Enzyme
- Cancer
John L. Farber focuses on Biochemistry, Cell killing, Mitochondrion, Mitochondrial permeability transition pore and Molecular biology.
His studies link Calcium with Biochemistry.
The Cell killing study combines topics in areas such as Lipid peroxidation, Catalase and Glutathione reductase.
Inner membrane is closely connected to Biophysics in his research, which is encompassed under the umbrella topic of Mitochondrion.
His Mitochondrial permeability transition pore research is multidisciplinary, incorporating elements of Cyclosporin a, Internal medicine and Muscle hypertrophy.
His Molecular biology study incorporates themes from Apoptosis, Cytochrome c, Specific activity and Cell biology.
His most cited work include:
- The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition (548 citations)
- Mechanisms of cell injury by activated oxygen species. (388 citations)
- Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischemic liver cell injury. (369 citations)
What are the main themes of his work throughout his whole career to date?
John L. Farber mainly focuses on Biochemistry, Cell killing, Internal medicine, Molecular biology and Pathology.
His studies deal with areas such as Lipid peroxidation, Oxidative stress, DNA damage and Mitochondrion, Cell biology as well as Cell killing.
The various areas that John L. Farber examines in his Mitochondrion study include Cyclosporin a, Biophysics and Mitochondrial permeability transition pore.
His work carried out in the field of Cell biology brings together such families of science as Apoptosis and Programmed cell death.
He works mostly in the field of Internal medicine, limiting it down to topics relating to Endocrinology and, in certain cases, Esophageal disease and Necrosis.
His Molecular biology study combines topics from a wide range of disciplines, such as Chromatin, Poly ADP ribose polymerase, DNA fragmentation and NAD+ kinase.
He most often published in these fields:
- Biochemistry (30.18%)
- Cell killing (24.26%)
- Internal medicine (20.71%)
What were the highlights of his more recent work (between 2009-2021)?
- Internal medicine (20.71%)
- Pathology (14.20%)
- Cancer research (10.06%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Internal medicine, Pathology, Cancer research, Immunology and Cancer.
His Internal medicine research integrates issues from Gastroenterology, Endocrinology and Cardiology.
The study incorporates disciplines such as Cell growth, Carcinogenesis, Inflammation, Esophageal cancer and Hyperplasia in addition to Cancer research.
In his research, Cell is intimately related to Apoptosis, which falls under the overarching field of Cell growth.
His biological study spans a wide range of topics, including Transplantation and Kidney transplantation.
His study in Muscle hypertrophy is interdisciplinary in nature, drawing from both Heart metabolism, Mitochondrion, Mitochondrial membrane transport protein and Mitochondrial permeability transition pore.
Between 2009 and 2021, his most popular works were:
- Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice (273 citations)
- CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy. (114 citations)
- GSK-3α is a central regulator of age-related pathologies in mice (97 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Cancer
- Internal medicine
John L. Farber spends much of his time researching Cancer research, Pathology, Cancer, Immunology and Internal medicine.
John L. Farber has included themes like Lung, Interstitial lung disease and mir-31 in his Pathology study.
His Immunology research incorporates elements of Transplantation and Kidney transplantation.
In his study, PPIF is inextricably linked to Endocrinology, which falls within the broad field of Internal medicine.
His work deals with themes such as Tumor progression, Cell, Apoptosis and Combination cancer therapy, which intersect with Carcinogenesis.
His Muscle hypertrophy study integrates concerns from other disciplines, such as Heart metabolism, Mitochondrion, Mitochondrial membrane transport protein and Mitochondrial permeability transition pore.
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