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Molecular Biology

D-Index
99
Citations
36883
World Ranking
553
National Ranking
302

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kay Huebner is affiliated with The Ohio State University in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology, cancer research, nutrition and dietetics, and oncology.

Their work spans several key topics including:

  • MicroRNA in disease regulation
  • Trace Elements in Health
  • Circular RNAs in diseases
  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • Genomics and Chromatin Dynamics

Huebner has contributed to multiple research papers, notably:

  • "Abrogation of esophageal carcinoma development in miR-31 knockout rats," published in 2020 in the Proceedings of the National Academy of Sciences
  • "Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo," published in 2023 in the Proceedings of the National Academy of Sciences
  • "Interaction of Wwox with Brca1 and associated complex proteins prevents premature resection at double-strand breaks and aberrant homologous recombination," published in 2021 in DNA Repair
  • "Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice," published in 2022 in the International Journal of Molecular Sciences

Frequent publication venues for Huebner include:

  • Proceedings of the National Academy of Sciences
  • DNA Repair
  • International Journal of Molecular Sciences

Some of the frequent co-authors collaborating with Huebner are Louise Y.Y. Fong, Ruiyan Jing, Karl J. Smalley, Oliver Fiehn, and John L. Farber.

In 2005, Huebner was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.

    Muller Fabbri;Ramiro Garzon;Amelia Cimmino;Amelia Cimmino;Zhongfa Liu

  • The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers

    Masataka Ohta;Hiroshi Inoue;Maria Grazia Cotticelli;Kumar Kastury

  • Molecular cloning of the interleukin-1 beta converting enzyme

    Douglas Pat Cerretti;Carl J. Kozlosky;Bruce Mosley;Nicole Nelson

  • Molecular cloning of a new transforming gene from a chemically transformed human cell line

    Colin S. Cooper;Morag Park;Donald G. Blair;Michael A. Tainsky

  • A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

    C.J. McMahan;J.L. Slack;B. Mosley;D. Cosman

  • The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer

    Gabriella Sozzi;Maria Luisa Veronese;Massimo Negrini;Raffaele Baffa

  • Cloning, Characterization, and Chromosomal Localization of a Human 5-HT6 Serotonin Receptor

    Ruth Kohen;Mark A. Metcalf;Naseem Khan;Teresa Druck

  • Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.

    Monika Tsai-Pflugfelder;Leroy F. Liu;Angela A. Liu;Kathleen M. Tewey

  • Replacement of Fhit in cancer cells suppresses tumorigenicity

    Zurab Siprashvili;Gabriella Sozzi;Larry D. Barnes;Peter McCue

  • Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA

    Stefano Volinia;Marco Galasso;Maria Elena Sana;Timothy F. Wise

  • Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV.

    James A. Hoxie;James D. Alpers;Jerome L. Rackowski;Kay Huebner

  • A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

    J Partanen;E Armstrong;T P Mäkelä;J Korhonen

  • Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice.

    John J. Moskow;Florencia Bullrich;Kay Huebner;Ira O. Daar

  • Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas

    Matthias Durst;Carlo M. Croce;Lutz Gissmann;Elisabeth Schwarz

  • Reprogramming of miRNA networks in cancer and leukemia

    Stefano Volinia;Marco Galasso;Stefan Costinean;Luca Tagliavini

  • Characterization of the Mammalian YAP (Yes-associated Protein) Gene and Its Role in Defining a Novel Protein Module, the WW Domain

    Marius Sudol;Peer Bork;Aaron Einbond;Kumar Kastury

  • Cloning of the ALL-1 Fusion Partner, the AF-6 Gene, Involved in Acute Myeloid Leukemias with the t(6;11) Chromosome Translocation

    R. Prasad;Y. Gu;H. Alder;T. Nakamura

  • Cloning and characterization of two members of the vertebrate Dlx gene family.

    A Simeone;D Acampora;M Pannese;M D'Esposito

  • elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints

    V. N. Rao;K. Huebner;M. Isobe;Abbas Ar-Rushdi

  • FHIT gene alterations in head and neck squamous cell carcinomas

    Laura Virgilio;Michele Shuster;Susanne M. Gollin;Maria Luisa Veronese

Frequent Co-Authors

Carlo M. Croce
Carlo M. Croce The Ohio State University
Teresa Druck
Teresa Druck The Ohio State University
Rami I. Aqeilan
Rami I. Aqeilan Hebrew University of Jerusalem
Hansjuerg Alder
Hansjuerg Alder The Ohio State University
Stefano Volinia
Stefano Volinia University of Ferrara
Dimitrios Iliopoulos
Dimitrios Iliopoulos University of California, Los Angeles
Massimo Negrini
Massimo Negrini University of Ferrara
Charles L. Shapiro
Charles L. Shapiro Icahn School of Medicine at Mount Sinai
Gabriella Sozzi
Gabriella Sozzi University of Milan
Koshi Mimori
Koshi Mimori Kyushu University

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