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Immunology

D-Index
42
Citations
25536
World Ranking
4863
National Ranking
2177

Overview

Wenda Gao is affiliated with Beth Israel Deaconess Medical Center in the United States. Their research contributions span multiple fields including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these domains, Gao's work largely focuses on Immunology, Molecular Biology, Infectious Diseases, Radiology, Nuclear Medicine and Imaging, and Physiology.

Their research encompasses key topics such as Monoclonal and Polyclonal Antibodies Research, IL-33, ST2, and ILC Pathways, Adenosine and Purinergic Signaling, Glycosylation and Glycoproteins Research, SARS-CoV-2 and COVID-19 Research, Phagocytosis and Immune Regulation, as well as Immune Cell Function and Interaction.

Frequent publication venues for Gao include:

  • Frontiers in Immunology
  • Antibody Therapeutics
  • Parasites & Vectors
  • Cancer Letters
  • Journal of Clinical Investigation

Regular collaborators in Gao's publications consist of:

  • Changchuin Mao
  • Simon C. Robson
  • Haohai Zhang
  • Lili Feng
  • Richard I. Near

Selected recent papers by Wenda Gao include:

  • The biology of VSIG4: Implications for the treatment of immune-mediated inflammatory diseases and cancer, 2022, Cancer Letters
  • Novel ELISA Protocol Links Pre-Existing SARS-CoV-2 Reactive Antibodies With Endemic Coronavirus Immunity and Age and Reveals Improved Serologic Identification of Acute COVID-19 via Multi-Parameter Detection, 2021, Frontiers in Immunology
  • The Pathogenic Roles of IL-22 in Colitis: Its Transcription Regulation by Musculin in T Helper Subsets and Innate Lymphoid Cells, 2021, Frontiers in Immunology
  • Glycoengineered anti-CD39 promotes anticancer responses by depleting suppressive cells and inhibiting angiogenesis in tumor models, 2022, Journal of Clinical Investigation
  • Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease, 2021, Cell Reports

Gao's body of work addresses mechanisms of immune regulation, inflammatory responses, and the role of antibodies and signaling molecules in disease contexts such as cancer, infectious diseases including COVID-19, and liver fibrosis. Their research approach crosses immunological signaling pathways and molecular biology, with implications for therapeutic strategies.

Best Publications

  • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.

    Estelle Bettelli;Yijun Carrier;Wenda Gao;Thomas Korn

  • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

    Silvia Deaglio;Karen M. Dwyer;Wenda Gao;David J Friedman

  • IL-21 initiates an alternative pathway to induce proinflammatory T H 17 cells

    Thomas Korn;Estelle Bettelli;Wenda Gao;Amit Awasthi

  • IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

    Valerie Dardalhon;Amit Awasthi;Hyoung-Joon Kwon;George Galileos

  • Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

    Thomas Korn;Jayagopala Reddy;Wenda Gao;Estelle Bettelli

  • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

    Joji Fujisaki;Juwell Wu;Juwell Wu;Alicia L. Carlson;Lev Silberstein

  • OX40 costimulation turns off Foxp3+ Tregs.

    Minh Diem Vu;Xiang Xiao;Wenda Gao;Nicolas Degauque

  • CD39 and control of cellular immune responses

    Karen M. Dwyer;Silvia Deaglio;Wenda Gao;David J. Friedman

  • Structures and biological functions of IL-31 and IL-31 receptors

    Qing Zhang;Prabhakar Putheti;Qiang Zhou;Quansheng Liu

  • Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen-Specific Regulatory T Cells

    W. Gao;Y. Lu;B. El Essawy;M. Oukka

  • CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice

    Xiaofeng Sun;Yan Wu;Wenda Gao;Keiichi Enjyoji

  • Urinary neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for renal tubulointerstitial injury in IgA nephropathy.

    Hanlu Ding;Yani He;Kailong Li;Jurong Yang

  • Expression of CD39 by Human Peripheral Blood CD4+CD25+ T Cells Denotes a Regulatory Memory Phenotype

    Karen M. Dwyer;Dusan Hanidziar;Prabhakar Putheti;Prue A Hill

  • PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for VH11/VH12 and phosphatidylcholine binding

    Xuemei Zhong;Joseph R. Tumang;Wenda Gao;Chunyan Bai

  • Stimulating PD-1-negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival.

    Wenda Gao;Gülçin Demirci;Terry B Strom;Xian Chang Li

  • Reciprocal generation of Th1/Th17 and Treg cells by B1 and B2 B cells

    Xuemei Zhong;Wenda Gao;Nicolas Degauque;Chunyan Bai

  • Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6.

    Wenda Gao;Lorraine Thompson;Qiang Zhou;Prabhakar Putheti

  • Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs

    Shipra Gupta;Thomas B. Thornley;Wenda Gao;Rafael Larocca

  • Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice.

    Nicolas Degauque;Christophe Mariat;James Kenny;Dong Zhang

  • Modulation of CD4+ T Lymphocyte Lineage Outcomes with Targeted, Nanoparticle-Mediated Cytokine Delivery

    Jason Park;Wenda Gao;Roy Whiston;Terry B. Strom

  • Heme oxygenase-1, carbon monoxide, and bilirubin induce tolerance in recipients toward islet allografts by modulating T regulatory cells

    Soo Sun Lee;Wenda Gao;Silvia Mazzola;Michael N. Thomas

Frequent Co-Authors

Terry B. Strom
Terry B. Strom Beth Israel Deaconess Medical Center
Simon C. Robson
Simon C. Robson Beth Israel Deaconess Medical Center
Mohamed Oukka
Mohamed Oukka University of Washington
Vijay K. Kuchroo
Vijay K. Kuchroo Harvard University
Thomas L. Rothstein
Thomas L. Rothstein Western Michigan University
Xian Chang Li
Xian Chang Li Cornell University
Thomas Korn
Thomas Korn Technical University of Munich
Raymond A. Sobel
Raymond A. Sobel Stanford University
Silvia Deaglio
Silvia Deaglio University of Turin
Xin Xiao Zheng
Xin Xiao Zheng University of Pittsburgh

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