World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
56
Citations
17535
World Ranking
3657
National Ranking
1434

Overview

Xin Xiao Zheng is affiliated with the University of Pittsburgh in the United States and focuses primarily on Medicine, with a specialized interest in Organic Chemistry, Molecular Biology, Biomedical Engineering, Food Science, and Oncology. Their research spans several disciplines, demonstrating a multidisciplinary approach to medical science.

Their work covers several main topics, including:

  • Protein Degradation and Inhibitors
  • Nanopore and Nanochannel Transport Studies
  • Microfluidic and Bio-sensing Technologies
  • Catalytic C-H Functionalization Methods
  • Cyclopropane Reaction Mechanisms
  • Proteins in Food Systems
  • Food Chemistry and Fat Analysis

Xin Xiao Zheng has contributed to various publication venues, with the most frequent being:

  • SSRN Electronic Journal
  • European Journal of Medicinal Chemistry
  • Analytical Chemistry
  • Organic Letters
  • Signal Transduction and Targeted Therapy

Some of their recent papers include:

  • "PROTAC: A promising technology for cancer treatment" (2020), published in European Journal of Medicinal Chemistry
  • "Development of Dual-Nanopore Biosensors for Detection of Intracellular Dopamine and Dopamine Efflux from Single PC12 Cell" (2022), published in Analytical Chemistry
  • "Ru(II)-Catalyzed Decarbonylative Alkylation and Annulations of Benzaldehydes with Iodonium Ylides under Chelation Assistance" (2022), published in Organic Letters
  • "Gefitinib (an EGFR tyrosine kinase inhibitor) plus anlotinib (an multikinase inhibitor) for untreated, EGFR-mutated, advanced non-small cell lung cancer (FL-ALTER): a multicenter phase III trial" (2024), published in Signal Transduction and Targeted Therapy
  • "Pyrimidine-fused Dinitrogenous Penta-heterocycles as a Privileged Scaffoldfor Anti-Cancer Drug Discovery" (2022), published in Current Topics in Medicinal Chemistry

The scientist frequently collaborates with other researchers, including Xiaohong Han, Ru Dong, Li-Ping Sun, Jinjing Chen, and Wanting Zhang, each having contributed to multiple joint publications.

Best Publications

  • The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

    Chen Zhu;Ana C Anderson;Anna Schubart;Huabao Xiong

  • Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augmented DNA Vaccination

    Dan H. Barouch;Sampa Santra;Jörn E. Schmitz;Marcelo J. Kuroda

  • Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance

    Alberto Sánchez-Fueyo;Jane Tian;Dominic Picarella;Christoph Domenig

  • Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

    Victor L Perez;Luk Van Parijs;Andre Biuckians;Xin Xiao Zheng

  • Mast cells are essential intermediaries in regulatory T-cell tolerance.

    Li Fan Lu;Evan F. Lind;David C. Gondek;Kathy A. Bennett

  • Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

    Catherine A Sabatos;Sumone Chakravarti;Eugene Cha;Anna Schubart

  • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

    Yongsheng Li;Xian Chang Li;Xin Xiao Zheng;Andrew D. Wells

  • Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

    Andrew D. Wells;Xian Chang Li;Yongsheng Li;Matthew C. Walsh

  • TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation

    Jennifer Hartt Meyers;Sumone Chakravarti;David Schlesinger;Zsolt Illes

  • TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

    William D. Hastings;David E. Anderson;Nasim Kassam;Ken Koguchi

  • Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation

    X X Zheng;A W Steele;P W Nickerson;W Steurer

  • Favorably Tipping the Balance between Cytopathic and Regulatory T Cells to Create Transplantation Tolerance

    Xin Xiao Zheng;Alberto Sánchez-Fueyo;Masayuki Sho;Christoph Domenig

  • The Th1/Th2 paradigm and the allograft response

    T. B. Strom;P. Roy-Chaudhury;R. Manfro;Xin Xiao Zheng

  • Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys

    Dan H. Barouch;Abie Craiu;Marcelo J. Kuroda;Jörn E. Schmitz

  • IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.

    Hēth R. Turnquist;Zhenlin Zhao;Brian R. Rosborough;Quan Liu;Quan Liu

  • Cytotoxic lymphocyte gene expression in peripheral blood leukocytes correlates with rejecting renal allografts.

    Vasconcellos Lm;Schachter Ad;Zheng Xx;Vasconcellos Lh

  • Ex vivo coating of islet cell allografts with murine CTLA4/Fc promotes graft tolerance.

    W. Steurer;P. W. Nickerson;A. W. Steele;J. Steiger

  • Tracking the immunoregulatory mechanisms active during allograft tolerance.

    Alberto Sánchez-Fueyo;Martina Weber;Christoph Domenig;Terry B. Strom

  • CTLA4 Signals Are Required to Optimally Induce Allograft Tolerance with Combined Donor-Specific Transfusion and Anti-CD154 Monoclonal Antibody Treatment

    Xin Xiao Zheng;Thomas G. Markees;Wayne W. Hancock;Yongsheng Li

  • Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis.

    Sylvie Ferrari-Lacraz;Eric Zanelli;Manfred Neuberg;Elina Donskoy

Frequent Co-Authors

Terry B. Strom
Terry B. Strom Beth Israel Deaconess Medical Center
Xian Chang Li
Xian Chang Li Cornell University
Peter Nickerson
Peter Nickerson University of Manitoba
Mohamed H. Sayegh
Mohamed H. Sayegh American University of Beirut
Vijay K. Kuchroo
Vijay K. Kuchroo Harvard University
Wayne W. Hancock
Wayne W. Hancock University of Pennsylvania
Laurence A. Turka
Laurence A. Turka Harvard University
Wenda Gao
Wenda Gao Beth Israel Deaconess Medical Center
Dan H. Barouch
Dan H. Barouch Harvard Medical School
Norman L. Letvin
Norman L. Letvin Beth Israel Deaconess Medical Center

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