Raymond A. Sobel

Overview

Best Publications

• B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

  Vijay K Kuchroo;Mercy Prabhu Das;Julia A Brown;Ann M Ranger

  2134
  Citations

• Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

  Laurent Monney;Catherine A. Sabatos;Jason L. Gaglia;Akemi Ryu

  1960
  Citations

• IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

  Valerie Dardalhon;Amit Awasthi;Hyoung-Joon Kwon;George Galileos

  1498
  Citations

• The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

  Sawsan Youssef;Olaf Stüve;Juan C. Patarroyo;Pedro J. Ruiz;Pedro J. Ruiz

  1373
  Citations

• Induction and molecular signature of pathogenic TH17 cells

  Youjin Lee;Amit Awasthi;Amit Awasthi;Nir Yosef;Nir Yosef;Francisco Javier Quintana

  1116
  Citations

• The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease.

  Dorothée Chabas;Sergio E. Baranzini;Dennis Mitchell;Claude C. A. Bernard

  1112
  Citations

• Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

  Anneli Jäger;Valérie Dardalhon;Raymond A. Sobel;Estelle Bettelli

  1056
  Citations

• Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

  Thomas Korn;Jayagopala Reddy;Wenda Gao;Estelle Bettelli

  1004
  Citations

• Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis

  Estelle Bettelli;Maria Pagany;Howard L. Weiner;Christopher Linington;Christopher Linington

  1002
  Citations

• PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells.

  Yvette E. Latchman;Spencer C. Liang;Yin Wu;Tatyana Chernova

  939
  Citations

• IL-10 Is Critical in the Regulation of Autoimmune Encephalomyelitis as Demonstrated by Studies of IL-10- and IL-4-Deficient and Transgenic Mice

  Estelle Bettelli;Mercy Prabhu Das;Edward D. Howard;Howard L. Weiner

  805
  Citations

• Protective and therapeutic role for αB-crystallin in autoimmune demyelination

  Shalina S. Ousman;Beren H. Tomooka;Johannes M. van Noort;Eric F. Wawrousek

  728
  Citations

• Loss of T-bet, But Not STAT1, Prevents the Development of Experimental Autoimmune Encephalomyelitis

  Estelle Bettelli;Brandon Sullivan;Susanne J. Szabo;Raymond A. Sobel;Raymond A. Sobel

  684
  Citations

• Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

  May H. Han;Sun-Il Hwang;Dolly B. Roy;Deborah H. Lundgren

  610
  Citations

• Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system.

  R. A. Sobel;M. E. Mitchell;G. Fondren

  569
  Citations

• Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.

  Vincent K Tuohy;Z. Lu;R. A. Sobel;R. A. Laursen

  537
  Citations

• Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

  Anneli Peters;Lisa A. Pitcher;Jenna M. Sullivan;Meike Mitsdoerffer

  527
  Citations

• Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

  Martin S Weber;Thomas Prod'homme;Sawsan Youssef;Shannon E Dunn

  523
  Citations

• An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis

  Lindsay B. Nicholson;Judith M. Greer;Raymond A. Sobel;Marjorie B. Lees

  518
  Citations

• Treatment of Autoimmune Neuroinflammation with a Synthetic Tryptophan Metabolite

  Michael Platten;Peggy P. Ho;Sawsan Youssef;Paulo Fontoura;Paulo Fontoura

  510
  Citations

• Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS.

  Dana H. Gabuzda;David D. Ho;Suzanne M. de la Monte;Martin S. Hirsch

  508
  Citations

• IL-10 is critical in the regulation of automimmune encephalomyelitis as demonstrated by studies of IL-10 and IL-4 deficient and transgenic mice

  E. Bettelli;M.P. Das;E. Howard;H. Weiner

  12
  Citations