World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
18642
World Ranking
14779
National Ranking
6181

Overview

Sheng Xiao is affiliated with Brigham and Women's Hospital in the United States. Their research primarily intersects the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a specific focus on subfields such as Molecular Biology, Immunology, Oncology, Hematology, and Genetics.

Their recent scholarly outputs include publications in prominent journals spanning several related domains. Notable papers are:

  • TIM-3 restrains anti-tumour immunity by regulating inflammasome activation, 2021, Nature
  • KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease, 2021, Cell Metabolism
  • B-cell-specific checkpoint molecules that regulate anti-tumour immunity, 2023, Nature
  • Foxo1 controls gut homeostasis and commensalism by regulating mucus secretion, 2021, The Journal of Experimental Medicine
  • Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation, 2020, Cell Reports

Sheng Xiao's research covers several main topics, including:

  • Galectins and Cancer Biology
  • Cancer-related molecular mechanisms research
  • Sarcoma Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Wnt/β-catenin signaling in development and cancer
  • CAR-T cell therapy research

Frequent coauthors collaborating with Sheng Xiao include:

  • Vijay K. Kuchroo
  • Aviv Regev
  • Jie Wen
  • Wentao Hu
  • Karen O. Dixon

Their research has been published repeatedly in some significant venues, such as:

  • Nature
  • Frontiers in Oncology
  • International Journal of Molecular Sciences
  • Genes Chromosomes and Cancer
  • Cell Metabolism

Sheng Xiao's portfolio indicates an interdisciplinary approach with a strong emphasis on understanding immune regulation mechanisms in cancer and other diseases, as well as exploring molecular biology aspects relevant to disease progression and treatment.

Best Publications

  • KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

    Brian P. Rubin;Samuel Singer;Connie Tsao;Anette Duensing

  • Induction and molecular signature of pathogenic TH17 cells

    Youjin Lee;Amit Awasthi;Amit Awasthi;Nir Yosef;Nir Yosef;Francisco Javier Quintana

  • Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.

    Nicole Joller;Ester Lozano;Patrick R. Burkett;Bonny Patel

  • Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1

    Chuan Wu;Nir Yosef;Nir Yosef;Theresa Thalhamer;Theresa Thalhamer;Chen Zhu

  • The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

    Lionel Apetoh;Francisco J Quintana;Caroline Pot;Nicole Joller

  • TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors.

    Brandon Lawrence;Antonio Perez-Atayde;Michele K. Hibbard;Brian P. Rubin

  • KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.

    Marcia L. Lux;Brian P. Rubin;Tara L. Biase;Chang Jie Chen

  • Dynamic regulatory network controlling Th17 cell differentiation

    Nir Yosef;Alex K. Shalek;Jellert T. Gaublomme;Hulin Jin

  • Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

    Sheng Xiao;Hulin Jin;Thomas Korn;Sue M. Liu

  • Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells

    Rahul Purwar;Christoph Schlapbach;Sheng Xiao;Hong Soon Kang

  • CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis

    Bing Zhu;Yoshio Bando;Sheng Xiao;Kaiyong Yang

  • FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome.

    Sheng Xiao;Srinivasa R. Nalabolu;Jon C. Aster;Junli Ma

  • Congenital Mesoblastic Nephroma t(12;15) Is Associated with ETV6-NTRK3 Gene Fusion Cytogenetic and Molecular Relationship to Congenital (Infantile) Fibrosarcoma

    Brian P. Rubin;Chang Jie Chen;Chang Jie Chen;Thomas W. Morgan;Sheng Xiao;Sheng Xiao

  • Bat3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion

    Manu Rangachari;Chen Zhu;Kaori Sakuishi;Sheng Xiao

  • Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis

    Benjamin D. Humphreys;Fengfeng Xu;Venkata Sabbisetti;Ivica Grgic

  • CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

    Chao Wang;Nir Yosef;Nir Yosef;Jellert Gaublomme;Jellert Gaublomme;Chuan Wu

  • Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells

    Chuan Wu;Theresa Thalhamer;Rafael F. Franca;Sheng Xiao

  • KIM-1–mediated phagocytosis reduces acute injury to the kidney

    Li Yang;Craig R. Brooks;Sheng Xiao;Venkata Sabbisetti

  • Aiolos promotes TH17 differentiation by directly silencing Il2 expression

    Francisco J Quintana;Hulin Jin;Evan J Burns;Meghan Nadeau

  • PLAG1 fusion oncogenes in lipoblastoma.

    Michele K. Hibbard;Harry P. Kozakewich;Paola Dal Cin;Raf Sciot

Frequent Co-Authors

Vijay K. Kuchroo
Vijay K. Kuchroo Harvard University
Jonathan A. Fletcher
Jonathan A. Fletcher Brigham and Women's Hospital
Nir Yosef
Nir Yosef University of California, Berkeley
Raymond A. Sobel
Raymond A. Sobel Stanford University
Samia J. Khoury
Samia J. Khoury American University of Beirut
Aviv Regev
Aviv Regev Genentech
Ana C. Anderson
Ana C. Anderson Brigham and Women's Hospital
Paola Dal Cin
Paola Dal Cin Harvard Medical School
Francisco J. Quintana
Francisco J. Quintana Harvard Medical School
Hongkun Park
Hongkun Park Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open the door to a wide variety of online degrees and careers in allied fields. For students looking to apply scientific knowledge in healthcare, fitness, or clinical roles, many flexible online programs are available.

Areas like public health, physiology, and health coaching are closely linked to biology. Students interested in exercise, wellness, or nutrition might consider an exercise science and nutrition degree online. Another pathway is online kinesiology programs, which emphasize movement science, rehabilitation, and human performance.

For those aiming for advanced clinical practice, certificate and post-master’s opportunities are available. Pursuing pmhnp online programs can lead to careers in psychiatric and mental health nursing. Cost-conscious graduates may look for the cheapest post master's fnp program to become a Family Nurse Practitioner.

Each pathway blends foundational biological sciences with specialized training. This enables graduates to pursue rewarding careers in healthcare, research, or wellness, all while offering the flexibility and accessibility of online learning.

Best Scientists Citing Sheng Xiao

Trending Scientists