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Maria Debiec-Rychter

Maria Debiec-Rychter

D-Index & Metrics

Genetics

D-Index
78
Citations
19193
World Ranking
1715
National Ranking
25

Overview

Maria Debiec-Rychter is affiliated with KU Leuven in Belgium and specializes in medicine with a focus on oncology and related disciplines. Their research encompasses several main fields including pulmonary and respiratory medicine, rheumatology, oncology, gastroenterology, and surgery. The scientist's subfields reflect a cross-disciplinary approach, emphasizing both clinical and molecular aspects of cancer and related diseases.

Their work covers a variety of topics, highlighting a broad interest in the biology and treatment of tumors along with related diagnostic and genomics challenges. Key research topics include:

  • Sarcoma diagnosis and treatment
  • Gastrointestinal tumor research and treatment
  • Soft tissue tumor case studies
  • Cancer genomics and diagnostics
  • Vascular tumors and angiosarcomas
  • IgG4-related and inflammatory diseases
  • Cardiac tumors and thrombi

Among the publication venues frequently selected by Maria Debiec-Rychter are:

  • Cancer Research
  • International Journal of Molecular Sciences
  • Gastrointestinal Stromal Tumor
  • European Journal of Cancer
  • Genes Chromosomes and Cancer

The scientist has collaborated repeatedly with several coauthors, including:

  • Raf Sciot
  • Patrick Schöffski
  • Agnieszka Woźniak
  • Che-Jui Lee
  • Piotr Rutkowski

Several recent papers define current research directions. These include:

  • "Long-term efficacy update of crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumour from EORTC trial 90101 CREATE," 2021, European Journal of Cancer
  • "Comprehensive targeted next-generation sequencing approach in the molecular diagnosis of gastrointestinal stromal tumor," 2020, Genes Chromosomes and Cancer
  • "Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors," 2020, Translational Oncology
  • "Loss of 9p21 Regulatory Hub Promotes Kidney Cancer Progression by Upregulating HOXB13," 2021, Molecular Cancer Research
  • "Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells," 2020, Scientific Reports

Best Publications

  • NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines.

    George D. Demetri;Robert S. Benjamin;Charles D. Blanke;Jean Yves Blay

  • KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

    Maria Debiec-Rychter;Raf Sciot;Axel Le Cesne;Marcus Schlemmer

  • Toward Minimal Residual Disease-Directed Therapy in Melanoma.

    Florian Rambow;Aljosja Rogiers;Oskar Marin-Bejar;Sara Aibar

  • Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

    Maria Debiec-Rychter;Jan Cools;Herlinde Dumez;Raf Sciot

  • Molecular and Clinical Analysis of Locally Advanced Dermatofibrosarcoma Protuberans Treated With Imatinib: Imatinib Target Exploration Consortium Study B2225

    Grant A. McArthur;George D. Demetri;Allan van Oosterom;Michael C. Heinrich

  • Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group

    M. Debiec-Rychter;H. Dumez;I. Judson;B. Wasag

  • Imatinib Mesylate in Advanced Dermatofibrosarcoma Protuberans: Pooled Analysis of Two Phase II Clinical Trials

    Piotr Rutkowski;Martine Van Glabbeke;Cathryn J Rankin;Wlodzimierz Ruka

  • PRCC-TFE3 renal carcinomas: morphologic, immunohistochemical, ultrastructural, and molecular analysis of an entity associated with the t(X;1)(p11.2;q21).

    Pedram Argani;Cristina R Antonescu;Jérôme Couturier;Jean-Christophe Fournet

  • Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma

    Munir R. Tanas;Andrea Sboner;Andre M. Oliveira;Michele R. Erickson-Johnson

  • Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.

    Hans Prenen;Jan Cools;Nicole Mentens;Cedric Folens

  • Risk Criteria and Prognostic Factors for Predicting Recurrences After Resection of Primary Gastrointestinal Stromal Tumor

    Piotr Rutkowski;Zbigniew I. Nowecki;Wanda Michej;Maria Dębiec-Rychter

  • Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor

    Arezoo Mohajeri;Johnbosco Tayebwa;Anna Collin;Jenny Nilsson

  • The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.

    Cheng-Han Lee;Adrian Mariño-Enriquez;Wenbin Ou;Meijun Zhu

  • Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity

    Maria Debiec-Rychter;Bartosz Wasag;Michel Stul;Ivo De Wever

  • Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

    Ophélia Maertens;Hans Prenen;Maria Debiec-Rychter;Agnieszka Wozniak

  • 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma

    Cheng-Han Lee;Wen-Bin Ou;Adrian Mariño-Enriquez;Meijun Zhu

  • Atypical Neurofibromas in Neurofibromatosis Type 1 Are Premalignant Tumors

    Eline Beert;Hilde Brems;Bruno Daniëls;Ivo De Wever

  • Crenolanib Inhibits the Drug-Resistant PDGFRA D842V Mutation Associated with Imatinib-Resistant Gastrointestinal Stromal Tumors

    Michael C Heinrich;Diana J Griffith;Arin McKinley;Janice Patterson

  • Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: A multicenter study on 54 cases

    Jerzy Lasota;Christopher L. Corless;Michael C. Heinrich;Maria Debiec-Rychter

  • Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)

    Anu Gupta;Srirupa Roy;Alexander J.F. Lazar;Wei Lien Wang

Frequent Co-Authors

Raf Sciot
Raf Sciot KU Leuven
Piotr Rutkowski
Piotr Rutkowski Maria Sklodowska-Curie National Research Institute of Oncology
Jean-Yves Blay
Jean-Yves Blay Claude Bernard University Lyon 1
Jonathan A. Fletcher
Jonathan A. Fletcher Brigham and Women's Hospital
Jan Cools
Jan Cools KU Leuven
Patrick Pauwels
Patrick Pauwels University of Antwerp

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