World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
8615
World Ranking
16319
National Ranking
680

Overview

Serge Benichou is affiliated with Grenoble Alpes University in France and conducts research primarily within the fields of immunology, microbiology, and medicine. The focus of their work predominantly covers HIV research, immune cell function, and related infectious diseases.

The main areas of study for Benichou's research include:

  • Immunology and Microbiology
  • Medicine

Their research spans subfields such as immunology, virology, infectious diseases, genetics, and animal science and zoology.

  • Immunology
  • Virology
  • Infectious Diseases
  • Genetics
  • Animal Science and Zoology

Benichou's work addresses several core topics, with an emphasis on HIV/AIDS and immune system interactions:

  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • HIV/AIDS Research and Interventions
  • Virus-based Gene Therapy Research
  • Animal Virus Infections Studies
  • Viral Gastroenteritis Research and Epidemiology
  • Reproductive System and Pregnancy

Notable recent publications include:

  • "Virus-Mediated Cell-Cell Fusion," 2020, published in the International Journal of Molecular Sciences
  • "Productive HIV-1 Infection of Tissue Macrophages by Fusion with Infected CD4+ T Cells," 2023, in The Journal of Cell Biology
  • "HIV-1 Cell-to-Cell Spread Overcomes the Virus Entry Block of Non-Macrophage-Tropic Strains in Macrophages," 2022, in PLoS Pathogens
  • "Macrophages: Key Cellular Players in HIV Infection and Pathogenesis," 2024, in Viruses
  • "Spermine and Spermidine Bind CXCR4 and Inhibit CXCR4- but Not CCR5-Tropic HIV-1 Infection," 2023, in Science Advances

Frequent co-authors who have contributed alongside Benichou include:

  • Marie Woottum
  • Mingyu Han
  • Bernard Lagane
  • Jean-Christophe Pagès
  • Maorong Xie

Benichou's research has been published multiple times in venues such as PLoS Pathogens, American Journal of Pathology, International Journal of Molecular Sciences, The Journal of Cell Biology, and Viruses.

  • PLoS Pathogens
  • American Journal Of Pathology
  • International Journal of Molecular Sciences
  • The Journal of Cell Biology
  • Viruses

Overall, Serge Benichou's work contributes to understanding the cellular mechanisms of HIV infection and immune responses, with a consistent focus on macrophages and virus-cell interactions within various biological and clinical contexts.

Best Publications

  • A Novel Human WD Protein, h-βTrCP, that Interacts with HIV-1 Vpu Connects CD4 to the ER Degradation Pathway through an F-Box Motif

    Florence Margottin;Stephan P Bour;Hervé Durand;Luc Selig

  • Nef Interacts with the μ Subunit of Clathrin Adaptor Complexes and Reveals a Cryptic Sorting Signal in MHC I Molecules

    Sylvie Le Gall;Lars Erdtmann;Serge Benichou;Clarisse Berlioz-Torrent

  • The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

    Stefan Arold;Peet Franken;Marie-Paule Strub;Francois Hoh

  • The Vpr protein from HIV-1: distinct roles along the viral life cycle.

    Erwann Le Rouzic;Serge Benichou

  • Human Immunodeficiency Virus Type 1 Vpr Protein Binds to the Uracil DNA Glycosylase DNA Repair Enzyme

    Mohamad Bouhamdan;S. Benichou;F. Rey;J.-M. Navarro

  • Differential Nucleocytoplasmic Shuttling of β-Arrestins CHARACTERIZATION OF A LEUCINE-RICH NUCLEAR EXPORT SIGNAL IN β-ARRESTIN2

    Mark G.H. Scott;Erwann Le Rouzic;Axel Périanin;Vincenzo Pierotti

  • The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 In vivo mutation rate.

    Louis M. Mansky;Sandra Preveral;Luc Selig;Richard Benarous

  • Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.

    S Benichou;M Bomsel;M Bodéus;H Durand

  • Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes.

    Ricardo Madrid;Sophie Le Maout;Marie‐Bénédicte Barrault;Katy Janvier

  • A Sequence in the N-terminal Region of Human Uracil-DNA Glycosylase with Homology to XPA Interacts with the C-terminal Part of the 34-kDa Subunit of Replication Protein A

    Toril A. Nagelhus;Terje Haug;Keshav K. Singh;Kylie F. Keshav

  • Interaction with the p6 Domain of the Gag Precursor Mediates Incorporation into Virions of Vpr and Vpx Proteins from Primate Lentiviruses

    L. Selig;J.-C. Pages;V. Tanchou;S. Prévéral

  • Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest.

    Luc Selig;Serge Benichou;Mark E. Rogel;Lily I. Wu

  • Vpr-mediated Incorporation of UNG2 into HIV-1 Particles Is Required to Modulate the Virus Mutation Rate and for Replication in Macrophages *

    Renxiang Chen;Erwann Le Rouzic;Jessica A. Kearney;Louis M. Mansky

  • Docking of HIV-1 Vpr to the Nuclear Envelope Is Mediated by the Interaction with the Nucleoporin hCG1

    Erwann G. Le Rouzic;Aurelie Mousnier;Cecilia Rustum;Cecilia Rustum;Francoise Stutz

  • Mechanisms for Cell-to-Cell Transmission of HIV-1.

    Lucie Bracq;Maorong Xie;Serge Benichou;Jérôme Bouchet

  • HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.

    Joshua L Andersen;Jason L DeHart;Erik S Zimmerman;Orly Ardon

  • Mutation of a Conserved Residue (D123) Required for Oligomerization of Human Immunodeficiency Virus Type 1 Nef Protein Abolishes Interaction with Human Thioesterase and Results in Impairment of Nef Biological Functions

    Lang Xia Liu;Nikolaus Heveker;Oliver T. Fackler;Stefan Theodor Arold

  • HIV-1 Vpr—a still “enigmatic multitasker”

    Carolin Alexandra Guenzel;Cecile Herate;Serge Benichou

  • Activation of the Rac-binding Partner FHOD1 Induces Actin Stress Fibers via a ROCK-dependent Mechanism *

    Judith E. Gasteier;Ricardo Madrid;Ellen Krautkrämer;Sebastian Schröder

  • Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation.

    Lang Xia Liu;Florence Margottin;Sylvie Le Gall;Olivier Schwartz

Frequent Co-Authors

John C. Guatelli
John C. Guatelli University of California, San Diego
Paul Jolicoeur
Paul Jolicoeur University of Montreal
Isabelle Maridonneau-Parini
Isabelle Maridonneau-Parini Federal University of Toulouse Midi-Pyrénées
Matthias Geyer
Matthias Geyer University of Bonn
Alexandre Benmerah
Alexandre Benmerah Institut Imagine
Oliver T. Fackler
Oliver T. Fackler University Hospital Heidelberg
Stefan T. Arold
Stefan T. Arold King Abdullah University of Science and Technology
Alain Schmitt
Alain Schmitt Institut Cochin
Olivier Schwartz
Olivier Schwartz Université Paris Cité
Christel Depienne
Christel Depienne Essen University Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in Biology or Biochemistry opens the door to a range of online degrees and career options in the healthcare and science fields. If you’re interested in hands-on patient care, you might consider pursuing one of the best online asn programs. These programs can be a pathway to becoming a registered nurse.

Those fascinated by nutrition and wellness may explore an online dietitian degree, which prepares graduates for careers in community health, clinical nutrition, and more.

For students interested in leadership and management in healthcare, consider enrolling in one of the top online mha programs that are cahme accredited. These programs can help you advance into healthcare administration roles.

If your goal is to reach the highest levels of nursing practice, the best online dnp programs offer flexible doctoral-level study options without traditional clinical requirements.

Each of these degrees leverages your foundation in biology and biochemistry, allowing you to tailor your career toward patient care, wellness, research, or healthcare management—all with the flexibility of online learning.

Best Scientists Citing Serge Benichou

Trending Scientists