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Molecular Biology

D-Index
56
Citations
14724
World Ranking
2191
National Ranking
1088

Research.com Recognitions

  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Thomas Lufkin is affiliated with Clarkson University in the United States. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology, with significant contributions in molecular biology and pathology and forensic medicine. Their work spans both clinical and experimental approaches related to spine and intervertebral disc pathology.

The scientist has published extensively on topics related to spine and intervertebral disc pathology, veterinary orthopedics and neurology, RNA research and splicing, musculoskeletal pain and rehabilitation, plant toxicity and pharmacological properties, cervical and thoracic myelopathy, as well as genetics and neurodevelopmental disorders.

Notable recent papers authored by Thomas Lufkin include:

  • Intervertebral disc degeneration-Current therapeutic options and challenges (2023) published in Frontiers in Public Health
  • Harmonization and standardization of nucleus pulposus cell extraction and culture methods (2023) published in JOR Spine
  • Development and Degeneration of the Intervertebral Disc-Insights from Across Species (2023) published in Veterinary Sciences
  • TTC9A deficiency induces estradiol-mediated changes in hippocampus and amygdala neuroplasticity-related gene expressions in female mice (2020) published in Brain Research Bulletin
  • Metal-Organic Framework as a Fluorescent and Colorimetric Dual-Signal Readout Biosensor Platform for the Detection of a Genetic Sequence from the SARS-CoV-2 Genome (2023) published in ACS Applied Materials & Interfaces

Their frequent coauthors reflect collaborations across related fields, and include:

  • Petra Kraus
  • Ankita Samanta
  • Sina Lufkin
  • Li Guan
  • Wing Shan Yu

Thomas Lufkin's publications have appeared in venues such as Frontiers in Public Health, JOR Spine, Veterinary Sciences, Brain Research Bulletin, and ACS Applied Materials & Interfaces, indicating a multidisciplinary reach spanning public health, spine research, veterinary science, neuroscience, and materials science applied to biological detection.

The scientist's research predominantly engages with clinical and molecular aspects of intervertebral disc biology and pathology, providing insights potentially relevant to both human and veterinary medicine.

Thomas Lufkin was recognized as a Fellow of the Alfred P. Sloan Foundation in 1994, reflecting a distinguished career milestone.

Best Publications

  • Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants

    C. Mendelsohn;D. Lohnes;D. Decimo;T. Lufkin

  • Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

    Thomas Lufkin;Andrée Dierich;Andrée Dierich;Marianne LeMeur;Marianne LeMeur;Manuel Mark;Manuel Mark

  • High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.

    Thomas Lufkin;David Lohnes;Manuel Mark;Andree Dierich

  • Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1.

    Jinqiu Zhang;Wai-Leong Tam;Wai-Leong Tam;Guo Qing Tong;Qiang Wu

  • Specification of jaw subdivisions by Dlx genes

    Michael J. Depew;Thomas Lufkin;John L. R. Rubenstein

  • Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb

    Bo Feng;Jianming Jiang;Jianming Jiang;Petra Kraus;Jia-Hui Ng

  • The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells.

    Jian-Chien Dominic Heng;Bo Feng;Jianyong Han;Jianming Jiang

  • A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

    Na-Yu Chia;Yun-Shen Chan;Yun-Shen Chan;Bo Feng;Xinyi Lu;Xinyi Lu

  • The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development

    Raymond F. Robledo;Lakshmi Rajan;Xue Li;Thomas Lufkin

  • Two rhombomeres are altered in Hoxa-1 mutant mice.

    Manuel Mark;Thomas Lufkin;Jean-Luc Vonesch;Esther Ruberte

  • Sprouty1 Is a Critical Regulator of GDNF/RET-Mediated Kidney Induction

    M. Albert Basson;M. Albert Basson;Simge Akbulut;Judy Watson-Johnson;Ruth Simon

  • Transcriptome analysis of zebrafish embryogenesis using microarrays.

    Sinnakaruppan Mathavan;Serene G. P Lee;Alicia Mak;Lance D Miller

  • Tbx3 improves the germ-line competency of induced pluripotent stem cells

    Jianyong Han;Ping Yuan;Henry Yang;Jinqiu Zhang

  • Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene.

    Thomas Lufkin;Manuel Mark;Charles P. Hart;Pascal Dollé

  • Mice deficient in cellular retinoic acid binding protein II (CRABPII) or in both CRABPI and CRABPII are essentially normal

    C. Lampron;C. Rochette-Egly;P. Gorry;P. Dolle

  • MicroRNA-134 Modulates the Differentiation of Mouse Embryonic Stem Cells, Where It Causes Post-Transcriptional Attenuation of Nanog and LRH1

    Yvonne M.‐S. Tay;Wai‐Leong Tam;Yen‐Sin Ang;Philip M. Gaughwin

  • The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen.

    Carla Tribioli;Thomas Lufkin

  • The Murine Otp Homeobox Gene Plays an Essential Role in the Specification of Neuronal Cell Lineages in the Developing Hypothalamus

    Weidong Wang;Thomas Lufkin

  • Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila.

    M. Frasch;Xiaowei Chen;T. Lufkin

  • Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene

    Weidong Wang;T. Van De Water;T. Lufkin

Frequent Co-Authors

Huck-Hui Ng
Huck-Hui Ng Genome Institute of Singapore
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Bing Lim
Bing Lim Thymmune Therapeutics
Manuel Mark
Manuel Mark Institute of Genetics and Molecular and Cellular Biology
Marianne LeMeur
Marianne LeMeur Institute of Genetics and Molecular and Cellular Biology
Andrée Dierich
Andrée Dierich Institute of Genetics and Molecular and Cellular Biology
Paul Robson
Paul Robson University of Connecticut
Lawrence W. Stanton
Lawrence W. Stanton Hamad bin Khalifa University
John L.R. Rubenstein
John L.R. Rubenstein University of California, San Francisco
Guillaume Bourque
Guillaume Bourque McGill University

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