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Genetics

D-Index
65
Citations
17704
World Ranking
2685
National Ranking
341

Overview

Maria Arranz is affiliated with King's College London in the United Kingdom. Their research spans multiple fields with a significant focus on medicine and biochemistry, genetics, and molecular biology. The scientist has produced a considerable body of work, particularly in psychiatry and mental health, molecular biology, epidemiology, cognitive neuroscience, and genetics.

The main research topics associated with Maria Arranz include:

  • Autism Spectrum Disorder Research
  • Attention Deficit Hyperactivity Disorder
  • Schizophrenia research and treatment
  • Genetic Associations and Epidemiology
  • Liver Disease Diagnosis and Treatment
  • Pharmacogenetics and Drug Metabolism
  • Drug Transport and Resistance Mechanisms

Recent publications by Maria Arranz and collaborators highlight their contributions to the fields of genetics, pharmacogenetics, and neuropsychiatric disorders. Notable papers include:

  • "A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex" (2022, Nature Genetics)
  • "Epigenome-wide association study of COVID-19 severity with respiratory failure" (2021, EBioMedicine)
  • "Novel genes and sex differences in COVID-19 severity" (2022, Human Molecular Genetics)
  • "Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder" (2021, Nature Communications)
  • "Pharmacogenetics of antipsychotics: Clinical utility and implementation" (2020, Behavioural Brain Research)

The scientist frequently collaborates with several researchers, including Amaia Hervás, Lucía Boix-Palop, Juliana Salazar, Sergio Aguilera, and Berta Almoguera. These collaborations reflect sustained interdisciplinary efforts across different specialties.

Maria Arranz's work has been published consistently in prominent venues, reflecting the range of their research interests. These venues include:

  • Pharmaceutics
  • Nature Genetics
  • Nature Communications
  • Translational Psychiatry
  • Communications Biology

The integration of genetics, molecular biology, and clinical application is evident in Maria Arranz's research profile, particularly through studies addressing psychiatric disorders such as autism spectrum disorder, ADHD, and schizophrenia, as well as investigations into pharmacogenetics and drug metabolism. Their contributions span both the understanding of complex diseases and the clinical implications for treatment and diagnosis.

Best Publications

  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Ditte Demontis;Ditte Demontis;Raymond K Walters;Raymond K Walters;Joanna Martin;Joanna Martin;Joanna Martin;Manuel Mattheisen

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders

    D. A. Collier;G. Stober;T. Li;A. Heils

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Pharmacogenetic prediction of clozapine response.

    M J Arranz;J Munro;J Birkett;A Bolonna

  • Pharmacogenetics and Pharmacogenomics of Schizophrenia: A Review of Last Decade of Research

    Maria Arranz;J de Leon

  • Association between clozapine response and allelic variation in 5-HT2A receptor gene

    Maria Arranz;David Collier;Monsheel S. Sodhi;David Ball

  • Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response

    M. J. Arranz;J. Munro;P. Sham;George Kirov

  • Evidence for association between polymorphisms in the promoter and coding regions of the 5-HT2A receptor gene and response to clozapine

    M. J. Arranz;J. Munro;Michael John Owen;G. Spurlock

  • Association between 5-HT2A gene promoter polymorphism and anorexia nervosa

    David A Collier;Maria J Arranz;Tao Li;Dennis Mupita

  • Complement genes contribute sex-biased vulnerability in diverse disorders

    Nolan Kamitaki;Nolan Kamitaki;Aswin Sekar;Aswin Sekar;Robert E. Handsaker;Robert E. Handsaker;Heather de Rivera;Heather de Rivera

  • Association between clozapine response and allelic variation in the 5-HT2C receptor gene.

    Monsheel S. Sodhi;Maria J. Arranz;David Curtis;David M. Ball

  • 5-HT2A and 5-HT2C Receptor Polymorphisms and Psychopathology in Late Onset Alzheimer's Disease

    Clive Holmes;Maria J. Arranz;John F. Powell;David A. Collier

  • Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder

    G Kirov;K C Murphy;M J Arranz;I Jones

  • Additional support for schizophrenia linkage on chromosomes 6 and 8: A multicenter study

    Dieter B. Wildenauer;Sibylle G. Schwab;Margot Albus;Joachim Hallmayer

  • Paternally inherited cis-regulatory structural variants are associated with autism.

    William M. Brandler;Danny Antaki;Madhusudan Gujral;Morgan L. Kleiber

  • High and low activity alleles of catechol-O-methyltransferase gene: ethnic difference and possible association with Parkinson's disease

    Hiroshi Kunugi;Shinichiro Nanko;Akira Ueki;Emiko Otsuka

  • Analysis of a structural polymorphism in the 5-HT2A receptor and clinical response to clozapine

    M. J. Arranz;D. A. Collier;J. Munro;P. Sham

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

Frequent Co-Authors

Robert Kerwin
Robert Kerwin King's College London
David A. Collier
David A. Collier Eli Lilly (United States)
Robin M. Murray
Robin M. Murray King's College London
George Kirov
George Kirov Cardiff University
Pak C. Sham
Pak C. Sham University of Hong Kong
Benedicto Crespo-Facorro
Benedicto Crespo-Facorro University of Seville
Elvira Bramon
Elvira Bramon University College London
David Curtis
David Curtis Queen Mary University of London
Maddy Parsons
Maddy Parsons King's College London
John Powell
John Powell King's College London

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