World's Best Scientists 2026 revealed!
Osamu Yoshie

Osamu Yoshie

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
50852
World Ranking
1137
National Ranking
66

Medicine

D-Index
106
Citations
50774
World Ranking
6429
National Ranking
148

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Osamu Yoshie is affiliated with Kindai University in Japan and has contributed significantly to several fields, primarily focusing on immunology, microbiology, and computer science. Their research output reflects an intersection of life sciences and computational methods, evident from the blend of topics and publication venues.

The scientist has explored a variety of topics including:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Chemokine receptors and signaling
  • Domain Adaptation and Few-Shot Learning
  • Multimodal Machine Learning Applications
  • Cytomegalovirus and herpesvirus research
  • Cancer Immunotherapy and Biomarkers

Yoshie's work spans multiple subfields with a strong emphasis on immunology and computer vision, including:

  • Immunology
  • Computer Vision and Pattern Recognition
  • Oncology
  • Artificial Intelligence
  • Radiology, Nuclear Medicine and Imaging

The scientist has published extensively in venues such as:

  • arXiv (Cornell University)
  • IUPHAR/BPS Guide to Pharmacology CITE
  • Cancers
  • International Immunology
  • Scientific Reports

Notable recent papers include:

  • "CCR4 as a Therapeutic Target for Cancer Immunotherapy," 2021, published in Cancers
  • "Multifaceted Roles of Chemokines and Chemokine Receptors in Tumor Immunity," 2021, published in Cancers
  • "Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury," 2020, published in Cellular and Molecular Immunology
  • "Recent Progress in Dendritic Cell-Based Cancer Immunotherapy," 2021, published in Cancers
  • "CCR4 Involvement in the Expansion of T Helper Type 17 Cells in a Mouse Model of Psoriasis," 2021, published in Journal of Investigative Dermatology

Cooperative research and frequent collaboration form a notable facet of Yoshie's work, with the most frequent co-authors being:

  • Takashi Nakayama
  • Kazuhiko Matsuo
  • Yuya Ieiri
  • Yuta Hara
  • Françoise Bachelerie

The main academic disciplines covered in Yoshie's research portfolio include:

  • Computer Science
  • Immunology and Microbiology
  • Medicine

Best Publications

  • Chemokines: A New Classification System and Their Role in Immunity

    Albert Zlotnik;Osamu Yoshie

  • Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

    Toshio Imai;Kunio Hieshima;Christopher Haskell;Masataka Baba

  • Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-lymphocytes

    Jean Michel Escola;Monique J. Kleijmeer;Willem Stoorvogel;Janice M. Griffith

  • Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

    Hiroyuki Hirai;Kazuya Tanaka;Osamu Yoshie;Kazuyuki Ogawa

  • International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors

    Francoise Bachelerie;Adit Ben-Baruch;Amanda M. Burkhardt;Christophe Combadiere

  • Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine

    Toshio Imai;Morio Nagira;Shin Takagi;Mayumi Kakizaki

  • Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow

    Alan M. Fong;Lisa A. Robinson;Douglas A. Steeber;Thomas F. Tedder

  • Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.

    Silvano Sozzani;Paola Allavena;Giovanna D’Amico;Walter Luini

  • The chemokine and chemokine receptor superfamilies and their molecular evolution

    Albert Zlotnik;Osamu Yoshie;Hisayuki Nomiyama

  • The T Cell-directed CC Chemokine TARC Is a Highly Specific Biological Ligand for CC Chemokine Receptor 4

    Toshio Imai;Masataka Baba;Miyuki Nishimura;Mayumi Kakizaki

  • Molecular Cloning of Human Eotaxin, an Eosinophil-selective CC Chemokine, and Identification of a Specific Eosinophil Eotaxin Receptor, CC Chemokine Receptor 3

    Motoji Kitaura;Toshihiro Nakajima;Toshio Imai;Shigenori Harada

  • Chemokines in immunity.

    Osamu Yoshie;Toshio Imai;Hisayuki Nomiyama

  • Identification of CCR6, the Specific Receptor for a Novel Lymphocyte-directed CC Chemokine LARC

    Masataka Baba;Toshio Imai;Miyuki Nishimura;Mayumi Kakizaki

  • A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection

    Tsutomu Murakami;Toshihiro Nakajima;Yoshio Koyanagi;Kazunobu Tachibana

  • Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

    Minako Ito;Kyoko Komai;Setsuko Mise-Omata;Mana Iizuka-Koga

  • Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7.

    Ryu Yoshida;Toshio Imai;Kunio Hieshima;Jun Kusuda

  • Selective expression of a novel surface molecule by human Th2 cells in vivo.

    Kinya Nagata;Kazuya Tanaka;Kazuyuki Ogawa;Kazumi Kemmotsu

  • Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2

    Kunio Hieshima;Toshio Imai;Ghislain Opdenakker;Jo Van Damme

  • Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis–like lesions

    Christian Vestergaard;Hiroyuki Yoneyama;Masako Murai;Kohichiro Nakamura

  • Chemokine/chemokine receptor nomenclature

    K. Bacon;M. Baggiolini;Hal Broxmeyer;R. Horuk

Frequent Co-Authors

Takashi Nakayama
Takashi Nakayama Kindai University
Toshio Imai
Toshio Imai Kindai University
Hisayuki Nomiyama
Hisayuki Nomiyama Kumamoto University
Kouji Matsushima
Kouji Matsushima Tokyo University of Science
Koichi Hirai
Koichi Hirai University of Tokyo
Albert Zlotnik
Albert Zlotnik University of California, Irvine
Philip M. Murphy
Philip M. Murphy National Institutes of Health
Yorio Hinuma
Yorio Hinuma Kyoto University
Akio Adachi
Akio Adachi Kansai Medical University

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