Koichi Hirai

Overview

Best Publications

• Expression and Function of Toll-Like Receptors in Eosinophils: Activation by Toll-Like Receptor 7 Ligand

  Hiroyuki Nagase;Shu Okugawa;Yasuo Ota;Masao Yamaguchi

  467
  Citations

• Inducible Expression of a Th2-Type CC Chemokine Thymus- and Activation-Regulated Chemokine by Human Bronchial Epithelial Cells

  Takashi Sekiya;Misato Miyamasu;Masako Imanishi;Hirokazu Yamada

  364
  Citations

• Th1- and Th2-Type Cytokines Regulate the Expression and Production of Eotaxin and RANTES by Human Lung Fibroblasts

  Luis M. Teran;Mitsuru Mochizuki;Joachim Bartels;Elba L. Valencia

  337
  Citations

• Molecular Cloning of a Novel Human CC Chemokine (Eotaxin-3) That Is a Functional Ligand of CC Chemokine Receptor 3 *

  Motoji Kitaura;Noriko Suzuki;Toshio Imai;Shin Takagi

  291
  Citations

• Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.

  Yuichiro Tsunemi;Hidehisa Saeki;Koichiro Nakamura;Takashi Sekiya

  266
  Citations

• Idiopathic pulmonary fibrosis and high prevalence of serum antibodies to hepatitis C virus.

  Takashi Ueda;Ken Ohta;Naohito Suzuki;Masao Yamaguchi

  251
  Citations

• Modulation of human basophil histamine release by hemopoietic growth factors.

  K Hirai;Y Morita;Y Misaki;K Ohta

  248
  Citations

• Expression of CXCR4 in Eosinophils: Functional Analyses and Cytokine-Mediated Regulation

  Hiroyuki Nagase;Misato Miyamasu;Masao Yamaguchi;Takao Fujisawa

  206
  Citations

• Chemokine production by the BEAS-2B human bronchial epithelial cells: Differential regulation of eotaxin, IL-8, and RANTES by TH2- and TH1-derived cytokines

  Takao Fujisawa;Yoshiko Kato;Jun Atsuta;Akihiko Terada

  200
  Citations

• Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells.

  Akiko Komiya;Hiroyuki Nagase;Hirokazu Yamada;Takashi Sekiya

  197
  Citations

• Chemokines induce eosinophil degranulation through CCR-3.

  Takao Fujisawa;Yoshiko Kato;Hiroyuki Nagase;Jun Atsuta

  192
  Citations

• Cytokine-mediated regulation of CXCR4 expression in human neutrophils.

  Hiroyuki Nagase;Misato Miyamasu;Masao Yamaguchi;Masako Imanishi

  174
  Citations

• Increased levels of a TH2‐type CC chemokine thymus and activation‐regulated chemokine (TARC) in serum and induced sputum of asthmatics

  T. Sekiya;H. Yamada;M. Yamaguchi;K. Yamamoto

  169
  Citations

• Attenuation of airway hyperresponsiveness in a murine asthma model by neutralization of granulocyte-macrophage colony-stimulating factor (GM-CSF).

  Naomi Yamashita;Hiroyuki Tashimo;Hirobumi Ishida;Fujito Kaneko

  155
  Citations

• Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages.

  Kuniko Nakayama;Shu Okugawa;Shintaro Yanagimoto;Takatoshi Kitazawa

  148
  Citations

• Elevated Levels of Eotaxin and interleukin-5 in Blister Fluid of Bullous Pemphigoid: Correlation With Tissue Eosinophilia

  M. Wakugawa;K. Nakamura;H. Hino;K. Toyama

  144
  Citations

• Growth inhibition of human lung cancer cell lines by interleukin 6 in vitro: a possible role in tumor growth via an autocrine mechanism.

  Hajime Takizawa;Takayuki Ohtoshi;Ken Ohta;Naomi Yamashita

  144
  Citations

• Presence of eotaxin in tears of patients with atopic keratoconjunctivitis with severe corneal damage.

  Kazumi Fukagawa;Toshiharu Nakajima;Kazuo Tsubota;Shigeto Shimmura

  142
  Citations

• Eotaxin is a potent chemotaxin for human basophils.

  Hirokazu Yamada;Koichi Hirai;Misato Miyamasu;Motoyasu Iikura

  140
  Citations

• Increased levels of a TH2-type CC chemokine thymus and activation-regulated chemokine (TARC) in serum and induced sputum of asthmatics

  Takashi Sekiya;Hirokazu Yamada;Masao Yamaguchi;Akira Ishii

  137
  Citations

• Enhancement of human basophil histamine release by interleukin 5.

  Koichi Hirai;Masao Yamaguchi;Yoshikata Misaki;Toshiaki Takaishi

  136
  Citations