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Medicine

D-Index
85
Citations
27840
World Ranking
14556
National Ranking
7368

Overview

Deborah J. Clegg is affiliated with Cedars-Sinai Medical Center in the United States and has contributed extensively to the field of medicine with a focus on pulmonary and respiratory medicine, physiology, nephrology, molecular biology, and endocrinology, diabetes, and metabolism.

Their research encompasses primary topics such as potassium and related disorders, renal function and acid-base balance, electrolyte and hormonal disorders, ion transport and channel regulation, diet and metabolism studies, adipose tissue and metabolism, and membrane-based ion separation techniques.

Frequent coauthors in their research include Biff F. Palmer, Juan Jesús Carrero, Pallavi Dubey, Sireesha Reddy, and Aaron P. Frank. Their work has been published predominantly in several journals, with the highest number of publications appearing in the Clinical Journal of the American Society of Nephrology, followed by the International Journal of Molecular Sciences, Mayo Clinic Proceedings, Kidney360, and the American Journal of Kidney Diseases.

Among recent scientific papers, several notable publications include:

  • Clinical Management of Hyperkalemia, 2020, Mayo Clinic Proceedings
  • Euglycemic Ketoacidosis as a Complication of SGLT2 Inhibitor Therapy, 2021, Clinical Journal of the American Society of Nephrology
  • Renal Tubular Acidosis and Management Strategies: A Narrative Review, 2020, Advances in Therapy
  • Kidney-Protective Effects of SGLT2 Inhibitors, 2022, Clinical Journal of the American Society of Nephrology
  • Association of Exposure to Phthalate Metabolites With Sex Hormones, Obesity, and Metabolic Syndrome in US Women, 2022, JAMA Network Open

Best Publications

  • The role of estrogens in control of energy balance and glucose homeostasis.

    Franck Mauvais-Jarvis;Deborah J. Clegg;Andrea L. Hevener

  • The sexual dimorphism of obesity

    Biff F. Palmer;Deborah J. Clegg

  • Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.

    William L. Holland;Benjamin T. Bikman;Li Ping Wang;Guan Yuguang

  • Obesity and cancer—mechanisms underlying tumour progression and recurrence

    Jiyoung Park;Thomas S. Morley;Min Kim;Deborah J. Clegg

  • Gonadal Hormones Determine Sensitivity to Central Leptin and Insulin

    Deborah J. Clegg;Lynda M. Brown;Stephen C. Woods;Stephen C. Benoit

  • The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Thomas W. Winkler;Anne E. Justice;Mariaelisa Graff;Llilda Barata

  • Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

    Yong Xu;Thekkethil P. Nedungadi;Liangru Zhu;Nasim Sobhani

  • Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

    Kelly A. Posey;Deborah J. Clegg;Richard L. Printz;Jaeman Byun

  • Silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus leads to metabolic syndrome

    Sergei Musatov;Walter Chen;Donald W. Pfaff;Charles V. Mobbs

  • The Catabolic Action of Insulin in the Brain Is Mediated by Melanocortins

    Stephen C. Benoit;Ellen L. Air;Lique M. Coolen;Richelle Strauss

  • Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia

    Kevin D. Niswender;Christopher D. Morrison;Deborah J. Clegg;Ryan Olson

  • Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

    Joshua C. Randall;Joshua C. Randall;Thomas W. Winkler;Zoltán Kutalik;Zoltán Kutalik;Sonja I. Berndt

  • Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents

    Stephen C. Benoit;Christopher J. Kemp;Carol F. Elias;William Abplanalp

  • Dietary ketosis enhances memory in mild cognitive impairment

    Robert Krikorian;Marcelle D. Shidler;Krista Dangelo;Sarah C. Couch

  • Insulin and leptin as adiposity signals.

    Stephen C Benoit;Deborah J Clegg;Randy J Seeley;Stephen C Woods

  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

    Tuomas O Kilpeläinen;M Carola Zillikens;Alena Stančákova;Francis M Finucane

  • Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity

    Elvira Haas;Indranil Bhattacharya;Eugen Brailoiu;Marlen Damjanović

  • Central effects of estradiol in the regulation of food intake, body weight, and adiposity

    L.M. Brown;D.J. Clegg

  • Differential Sensitivity to Central Leptin and Insulin in Male and Female Rats

    Deborah J. Clegg;Christine A. Riedy;Kathleen A. Blake Smith;Stephen C. Benoit

  • Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

    Joshua C. Randall;Thomas W. Winkler;Zoltan Kutalik;Sonja I. Berndt

Frequent Co-Authors

Stephen C. Benoit
Stephen C. Benoit University of Cincinnati
Stephen C. Woods
Stephen C. Woods University of Cincinnati
Randy J. Seeley
Randy J. Seeley University of Michigan–Ann Arbor
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
Unnur Thorsteinsdottir
Unnur Thorsteinsdottir deCODE Genetics (Iceland)
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
Inês Barroso
Inês Barroso University of Exeter
Alan R. Shuldiner
Alan R. Shuldiner University of Maryland, Baltimore
Claes Ohlsson
Claes Ohlsson University of Gothenburg
Markus Perola
Markus Perola Finnish Institute for Health and Welfare

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