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Medicine

D-Index
102
Citations
34325
World Ranking
7728
National Ranking
4021

Overview

Graham Casey is affiliated with the University of Virginia in the United States and has an extensive publication record primarily focused on the study of colorectal cancer and related genetic and molecular biological factors. Their research spans multiple intersecting fields, including medicine, biochemistry, genetics, and molecular biology, with significant contributions to subfields such as genetics, molecular biology, pathology and forensic medicine, oncology, and cancer research.

Their recent scholarly work includes studies published between 2020 and 2022, addressing genetic risk modeling, adiposity, metabolism, and therapeutic interventions associated with cancer risk. Notable papers include:

  • Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk (2020) published in The American Journal of Human Genetics
  • Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study (2020) published in BMC Medicine
  • Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses (2020) published in BMC Medicine
  • Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer (2021) published in JNCI Cancer Spectrum
  • Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis (2022) published in PLoS Medicine

Their research frequently appears in the following publication venues:

  • Cancer Epidemiology Biomarkers & Prevention
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Cancer Research
  • JNCI Journal of the National Cancer Institute

Coauthorship is an important aspect of their work, including frequent collaborations with notable researchers such as Ulrike Peters, Víctor Moreno, Stephen B. Gruber, Mark A. Jenkins, and Peter T. Campbell.

Their main topics of research encompass genetic factors in colorectal cancer, genetic associations and epidemiology, colorectal cancer screening and detection, cancer metabolism, liver disease diagnosis and treatment, cancer-related molecular mechanisms, and RNA modifications related to cancer.

  • Genetic factors in colorectal cancer
  • Genetic Associations and Epidemiology
  • Colorectal Cancer Screening and Detection
  • Cancer, Lipids, and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer

Graham Casey's publication volume across these areas reflects an integration of genetic epidemiology and molecular studies advancing understanding of cancer biology, particularly focusing on colorectal cancer risk and detection methodologies.

Best Publications

  • Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

    Dalila Pinto;Elsa Delaby;Elsa Delaby;Elsa Delaby;Daniele Merico;Mafalda Barbosa

  • Lysophosphatidic Acid as a Potential Biomarker for Ovarian and Other Gynecologic Cancers

    Yan Xu;Zhongzhou Shen;Donald W. Wiper;Minzhi Wu

  • Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant

    Anatoly Urisman;Ross J Molinaro;Ross J Molinaro;Nicole Fischer;Sarah J Plummer

  • Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency: Familial Colorectal Cancer Type X

    Noralane M. Lindor;Kari Rabe;Gloria M. Petersen;Robert Haile

  • CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

    Hui Ling;Riccardo Spizzo;Yaser Atlasi;Milena Nicoloso

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

    Ali Amin Al Olama;Zsofia Kote-Jarai;Sonja I. Berndt;David V. Conti

  • Principles for the post-GWAS functional characterization of cancer risk loci

    Matthew L Freedman;Alvaro N A Monteiro;Simon A Gayther;Simon A Gayther;Gerhard A Coetzee

  • Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Bryony A Thompson;Bryony A Thompson;Amanda B Spurdle;John-Paul Plazzer;Marc S Greenblatt

  • Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

    Aung Ko Win;Mark A. Jenkins;James G Dowty;Antonis C Antoniou

  • Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients.

    Y Xu;D C Gaudette;J D Boynton;A Frankel

  • Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6.

    Jeffrey M. Trent;Eric J. Stanbridge;Heyoung L. McBride;Eckart U. Meese

  • Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study.

    Mark A. Jenkins;Shinichi Hayashi;Anne Marie O'Shea;Lawrence J. Burgart

  • Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study

    Aung Ko Win;Joanne P Young;Noralane M Lindor;Katherine M. Tucker

  • RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases.

    Graham Casey;Phillippa J. Neville;Sarah J. Plummer;Ying Xiang

  • Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

    Ulrike Peters;Ulrike Peters;Shuo Jiao;Fredrick R. Schumacher;Carolyn M. Hutter;Carolyn M. Hutter

  • The landscape of recombination in African Americans

    Anjali G. Hinch;Arti Tandon;Arti Tandon;Nick Patterson;Yunli Song

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

    Dalila Pinto;Elsa Delaby;Daniele Merico;Mafalda Barbosa

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

Frequent Co-Authors

Polly A. Newcomb
Polly A. Newcomb Fred Hutchinson Cancer Research Center
John D. Potter
John D. Potter Massey University
Mark A. Jenkins
Mark A. Jenkins University of Melbourne
John L. Hopper
John L. Hopper University of Melbourne
Loic Le Marchand
Loic Le Marchand University of Hawaii at Manoa
Robert W. Haile
Robert W. Haile Stanford University
David V. Conti
David V. Conti University of Southern California
John S. Witte
John S. Witte Stanford University
Sonja I. Berndt
Sonja I. Berndt National Institutes of Health

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