World's Best Scientists 2026 revealed!

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Medicine

D-Index
95
Citations
32038
World Ranking
10095
National Ranking
5198

Overview

John S. Witte is affiliated with Stanford University in the United States. Their research spans multiple fields primarily within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed extensively to genetics, pulmonary and respiratory medicine, molecular biology, oncology, and cancer research.

Their work covers several main topics including genetic associations and epidemiology, prostate cancer treatment and research, BRCA gene mutations in cancer, prostate cancer diagnosis and treatment, cancer genomics and diagnostics, genetic factors in colorectal cancer, and epigenetics and DNA methylation.

Among the recent published papers by John S. Witte are the following:

  • Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts (2020, Nature Communications)
  • Principles and methods for transferring polygenic risk scores across global populations (2023, Nature Reviews Genetics)
  • Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction (2020, Nature Communications)
  • Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts (2021, Nature Communications)
  • The landscape of host genetic factors involved in immune response to common viral infections (2020, Genome Medicine)

Frequently collaborating coauthors include:

  • Linda Kachuri
  • Rebecca E. Graff
  • Travis J. Meyers
  • David V. Conti
  • Sara R. Rashkin

John S. Witte's publications often appear in notable scientific venues, with frequent placements in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Urology
  • UNC Libraries
  • Cancer Research
  • Nature Communications

Best Publications

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.

    G Riethmüller;E Holz;G Schlimok;W Schmiegel

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

    Manuel A. Ferreira;Judith M. Vonk;Hansjörg Baurecht;Ingo Marenholz;Ingo Marenholz

  • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

    Ali Amin Al Olama;Zsofia Kote-Jarai;Sonja I. Berndt;David V. Conti

  • Point: Population Stratification: A Problem for Case-Control Studies of Candidate-Gene Associations?

    Duncan C. Thomas;John S. Witte

  • The health effects of swimming in ocean water contaminated by storm drain runoff.

    Robert W. Haile;John S. Witte;Mark Gold;Ron Cressey

  • Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

    Jonathan B. Singer;Annie E. Hill;Lindsay C. Burrage;Keith R. Olszens

  • RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases.

    Graham Casey;Phillippa J. Neville;Sarah J. Plummer;Ying Xiang

  • The landscape of recombination in African Americans

    Anjali G. Hinch;Arti Tandon;Arti Tandon;Nick Patterson;Yunli Song

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance.

    Brian Kwok;Jeff M. Hall;John S. Witte;Yin Xu

  • CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B 5′‐promoter region polymorphism

    Christoph Wandel;Christoph Wandel;John S. Witte;John S. Witte;Jefferey M. Hall;Jefferey M. Hall;C. Michael Stein;C. Michael Stein

  • Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent

    Timothy R. Rebbeck;Susan S. Devesa;Bao-Li Chang;Clareann H. Bunker

  • Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas.

    H J Lin;N M Probst-Hensch;A D Louie;I H Kau

  • Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast.

    Kari Bohlke;Daniel W. Cramer;Dimitrios Trichopoulos;Christos S. Mantzoros

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

    Keri L. Monda;Keri L. Monda;Gary K. Chen;Kira C. Taylor;Kira C. Taylor;Cameron Palmer;Cameron Palmer

  • Genetic dissection of complex traits.

    John S. Witte;Robert C. Elston;Nicholas J. Schork

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

Frequent Co-Authors

Graham Casey
Graham Casey University of Virginia
Esther M. John
Esther M. John Stanford University
Christopher A. Haiman
Christopher A. Haiman University of Southern California
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health
David V. Conti
David V. Conti University of Southern California
Eric A. Klein
Eric A. Klein Cleveland Clinic
Sue A. Ingles
Sue A. Ingles University of Southern California
Stephen K. Van Den Eeden
Stephen K. Van Den Eeden Kaiser Permanente
Sonja I. Berndt
Sonja I. Berndt National Institutes of Health

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