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Biology and Biochemistry

D-Index
59
Citations
59425
World Ranking
12234
National Ranking
874

Overview

Ralf Herwig is affiliated with the Max Planck Society in Germany and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Medicine. Their research spans various subfields, including Molecular Biology, Computational Theory and Mathematics, Genetics, Surgery, and Physiology.

The main topics covered in their work include Computational Drug Discovery Methods, Bioinformatics and Genomic Networks, RNA modifications and cancer, Pancreatic function and diabetes, Genomics and Phylogenetic Studies, Chronic Lymphocytic Leukemia Research, and RNA Research and Splicing.

Ralf Herwig's recent publications encompass a range of influential papers in high-impact journals. Notable works include:

  • Systematic assessment of long-read RNA-seq methods for transcript identification and quantification, 2024, Nature Methods
  • Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies, 2022, Blood
  • ConsensusPathDB 2022: molecular interactions update as a resource for network biology, 2021, Nucleic Acids Research
  • Crowdsourced mapping of unexplored target space of kinase inhibitors, 2021, Nature Communications
  • NetCore: a network propagation approach using node coreness, 2020, Nucleic Acids Research

Their frequent publication venues reflect a consistent presence in journals that focus on molecular biology, bioinformatics, and related disciplines. These venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • International Journal of Molecular Sciences
  • NAR Genomics and Bioinformatics

Collaboration is also a marked feature of Ralf Herwig's research activity. Frequent co-authors include Matthias Lienhard, Bernd Timmermann, Kristina Thedinga, Paul Prasse, and Alexandra Chadt, indicating active collaboration within their research community.

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • An integrated map of genetic variation from 1,092 human genomes

    Goncalo R Abecasis;Adam Auton;Lisa D Brooks

  • Table S2: Trans-factors and trinucleotide repeat instability Trans-factor

    Arturo López Castel;John D Cleary;Christopher E Pearson

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Systems Biology in Practice: Concepts, Implementation and Application

    Edda Klipp;Ralf Herwig;Axel Kowald;Christoph Wierling

  • The ConsensusPathDB interaction database: 2013 update

    Atanas Kamburov;Ulrich Stelzl;Hans Lehrach;Ralf Herwig

  • ConsensusPathDB: toward a more complete picture of cell biology

    Atanas Kamburov;Konstantin Pentchev;Hanna Galicka;Christoph K. Wierling

  • ConsensusPathDB—a database for integrating human functional interaction networks

    Atanas Kamburov;Christoph K. Wierling;Hans Lehrach;Ralf Herwig

  • A map of human genome variation from population-scale sequencing

    Richard M. Durbin;David L. Altshuler;Gonçalo R. Abecasis;David R. Bentley

  • Systems Biology: A Textbook

    Edda Klipp;Wolfram Liebermeister;Christoph Wierling;Axel Kowald

  • Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

    Yasmin Babaie;Ralf Herwig;Boris Greber;Thore C. Brink

  • Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA

    Atanas Kamburov;Rachel Cavill;Timothy M. D. Ebbels;Ralf Herwig

  • Analyzing and interpreting genome data at the network level with ConsensusPathDB.

    Ralf Herwig;Christopher Hardt;Matthias Lienhard;Atanas Kamburov

  • MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments

    Matthias Lienhard;Christina Grimm;Markus Morkel;Ralf Herwig

  • Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

    Moritz Schütte;Thomas Risch;Nilofar Abdavi-Azar;Karsten Boehnke

  • Transcript Level Alterations Reflect Gene Dosage Effects Across Multiple Tissues in a Mouse Model of Down Syndrome

    Pascal Kahlem;Marc Sultan;Ralf Herwig;Matthias Steinfath

  • Large-Scale Clustering of cDNA-Fingerprinting Data

    Ralf Herwig;Albert J. Poustka;Christine Müller;Christof Bull

  • DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro

    Marcha C.T. Verheijen;Matthias Lienhard;Yannick Schrooders;Olivia Clayton

  • Primary Differentiation in the Human Blastocyst: Comparative Molecular Portraits of Inner Cell Mass and Trophectoderm Cells

    James Adjaye;John Huntriss;Ralf Herwig;Alia BenKahla

Frequent Co-Authors

Hans Lehrach
Hans Lehrach Max Planck Society
Georg Bartsch
Georg Bartsch University of Innsbruck
Bernd Timmermann
Bernd Timmermann Max Planck Society
Jos C. S. Kleinjans
Jos C. S. Kleinjans Maastricht University
Edda Klipp
Edda Klipp Humboldt-Universität zu Berlin
James Adjaye
James Adjaye University College London
Lukas Chavez
Lukas Chavez University of California, San Diego
Marie-Laure Yaspo
Marie-Laure Yaspo Max Planck Society
Xiaodong Fang
Xiaodong Fang Beijing Genomics Institute
Steven A. McCarroll
Steven A. McCarroll Harvard University

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