James Adjaye

What is he best known for?

The fields of study he is best known for:

• Gene
• DNA
• Cellular differentiation

The scientist’s investigation covers issues in Cell biology, Induced pluripotent stem cell, Embryonic stem cell, Reprogramming and Molecular biology. He has included themes like Cellular differentiation, Transcriptome, Mesoderm, Germ cell and Differential display in his Cell biology study. Induced pluripotent stem cell is a primary field of his research addressed under Genetics.

His research on Embryonic stem cell often connects related topics like Stem cell. His study explores the link between Reprogramming and topics such as Mitochondrial biogenesis that cross with problems in Somatic cell, Regulation of gene expression and Cell type. His study focuses on the intersection of Molecular biology and fields such as Gene with connections in the field of In vivo and Embryo.

His most cited work include:

• The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. (460 citations)
• Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells (314 citations)
• Fibroblast Growth Factor 2 Modulates Transforming Growth Factor β Signaling in Mouse Embryonic Fibroblasts and Human ESCs (hESCs) to Support hESC Self‐Renewal (219 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Induced pluripotent stem cell, Embryonic stem cell, Genetics and Molecular biology. His Cell biology research is multidisciplinary, incorporating elements of Cell culture, Transcriptome and Cellular differentiation, Adult stem cell. His Induced pluripotent stem cell research integrates issues from SOX2, Reprogramming, Stem cell and Somatic cell.

His work in SOX2 tackles topics such as Homeobox protein NANOG which are related to areas like Transcription factor. His Embryoid body and Rex1 study in the realm of Embryonic stem cell connects with subjects such as Amniotic fluid. His Molecular biology study combines topics from a wide range of disciplines, such as Mutation, KOSR and DNA sequencing.

He most often published in these fields:

• Cell biology (67.67%)
• Induced pluripotent stem cell (63.91%)
• Embryonic stem cell (44.36%)

What were the highlights of his more recent work (between 2013-2021)?

• Induced pluripotent stem cell (63.91%)
• Cell biology (67.67%)
• SOX2 (33.08%)

In recent papers he was focusing on the following fields of study:

James Adjaye spends much of his time researching Induced pluripotent stem cell, Cell biology, SOX2, Transcriptome and KLF4. His Induced pluripotent stem cell research incorporates themes from Cell culture, Cellular differentiation, Somatic cell, Reprogramming and Mesenchymal stem cell. His studies deal with areas such as Embryonic stem cell, Downregulation and upregulation, Cell type and Immunology as well as Cell biology.

He focuses mostly in the field of SOX2, narrowing it down to topics relating to Homeobox protein NANOG and, in certain cases, LIN28. His Transcriptome study necessitates a more in-depth grasp of Genetics. The KLF4 study which covers In vivo that intersects with Mutation and DNA repair.

Between 2013 and 2021, his most popular works were:

• HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2 (165 citations)
• Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks (94 citations)
• Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks (94 citations)

In his most recent research, the most cited papers focused on:

• Gene
• DNA
• Cellular differentiation

His scientific interests lie mostly in Cell biology, Induced pluripotent stem cell, Alzheimer's disease, Transcriptome and Genetics. His work deals with themes such as Adult stem cell, Reprogramming, Downregulation and upregulation, Messenger RNA and microRNA, which intersect with Cell biology. His Reprogramming research is multidisciplinary, relying on both Mitochondrion, Regenerative medicine, Cellular differentiation and Somatic cell.

His Downregulation and upregulation study combines topics from a wide range of disciplines, such as Embryonic stem cell, Proteome and Cell fate determination. James Adjaye has included themes like Stem cell, Neural stem cell and Neuroscience in his Induced pluripotent stem cell study. His studies in Alzheimer's disease integrate themes in fields like Cell culture, GSK3B, GSK-3 and Proteasome.