His primary scientific interests are in RNA, Coronavirus, Furin, Virology and RNA-dependent RNA polymerase. His work deals with themes such as Molecular biology, Polymerase and Exon, which intersect with RNA. His study explores the link between Molecular biology and topics such as Methylation that cross with problems in NSP1 and Viral protein.
His study focuses on the intersection of Furin and fields such as Glycoprotein with connections in the field of Peptide sequence and In vitro. His Virology study typically links adjacent topics like Genomics. His Viral replication study incorporates themes from RNA virus and Rossmann fold.
Etienne Decroly focuses on Virology, RNA, Molecular biology, Biochemistry and Coronavirus. His research combines RNA polymerase and Virology. His RNA study integrates concerns from other disciplines, such as Methylation, Methyltransferase and Polymerase.
The Glycoprotein and Furin research he does as part of his general Molecular biology study is frequently linked to other disciplines of science, such as Gp41, therefore creating a link between diverse domains of science. His work carried out in the field of Furin brings together such families of science as Wild type and Viral entry. His work in the fields of Biochemistry, such as Binding site, Enzyme, Oligonucleotide and Guanylyltransferase, overlaps with other areas such as Vesicle.
Etienne Decroly mainly investigates RNA, Virology, Coronavirus, Virus and Methyltransferase. His research on RNA concerns the broader Genetics. His study in Virology is interdisciplinary in nature, drawing from both RNA polymerase and RNA capping.
Etienne Decroly studied Coronavirus and Severe acute respiratory syndrome coronavirus 2 that intersect with Human coronavirus and Pandemic. His studies deal with areas such as Sudan Ebola virus, Flavivirus, Transition and Binding site as well as Methyltransferase. His Cleavage course of study focuses on Peptide sequence and Furin and Glycoprotein.
Coronavirus, RNA, Polymerase, Virology and Methylation are his primary areas of study. Etienne Decroly has included themes like Viral replication and Exon in his RNA study. Virology and RNA polymerase are frequently intertwined in his study.
His Methylation study combines topics in areas such as Chemical biology and Cell biology. His Genome study combines topics from a wide range of disciplines, such as Peptide sequence, Cleavage, Protein structure and Glycoprotein. Etienne Decroly studies Furin, a branch of Genetics.
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The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade.
B. Coutard;C. Valle;X. de Lamballerie;B. Canard.
Antiviral Research (2020)
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
Lorenzo Subissi;Clara C. Posthuma;Axelle Collet;Jessika C. Zevenhoven-Dobbe.
Proceedings of the National Academy of Sciences of the United States of America (2014)
The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.
Snijder Ej;Decroly E;Ziebuhr J.
Advances in Virus Research (2016)
Conventional and unconventional mechanisms for capping viral mRNA
Etienne Decroly;François Ferron;Julien Lescar;Julien Lescar;Bruno Canard.
Nature Reviews Microbiology (2012)
Structure and functionality in flavivirus NS-proteins: Perspectives for drug design
Michela Bollati;Karin Alvarez;René Assenberg;Cécile Baronti.
Antiviral Research (2010)
In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication.
Franck Touret;Magali Gilles;Karine Barral;Antoine Nougairède.
Scientific Reports (2020)
Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex
Etienne Decroly;Claire Debarnot;François Ferron;Mickael Bouvet.
PLOS Pathogens (2011)
Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity
Etienne Decroly;Isabelle Imbert;Bruno Coutard;Mickaël Bouvet.
Journal of Virology (2008)
Maturation of HIV envelope glycoprotein precursors by cellular endoproteases.
Maxime Moulard;Etienne Decroly;Etienne Decroly.
Biochimica et Biophysica Acta (2000)
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.
Ashleigh Shannon;Nhung Thi-Tuyet Le;Barbara Selisko;Cecilia Eydoux.
Antiviral Research (2020)
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