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Biology and Biochemistry

D-Index
50
Citations
10682
World Ranking
17535
National Ranking
756

Overview

Bruno Coutard is affiliated with Aix-Marseille University in France, focusing primarily on medicine with a significant emphasis on infectious diseases. Their research spans molecular biology, public health, environmental and occupational health, insect science, and cardiology and cardiovascular medicine.

The scientist's main fields of study include:

  • Medicine

Subfields of study covered in their research are:

  • Infectious Diseases
  • Molecular Biology
  • Public Health, Environmental and Occupational Health
  • Insect Science
  • Cardiology and Cardiovascular Medicine

The central themes of Bruno Coutard's work encompass:

  • SARS-CoV-2 and COVID-19 Research
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • COVID-19 Clinical Research Studies
  • Viral gastroenteritis research and epidemiology
  • Viral Infections and Immunology Research
  • SARS-CoV-2 detection and testing

Their publication record includes a number of influential articles in virology and infectious diseases research. Notable recent papers are:

  • The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade (2020, Antiviral Research)
  • Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis (2020, Nature)
  • In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication (2020, Scientific Reports)
  • Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis (2020, Nature Communications)
  • Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity (2022, Journal of Virology)

Bruno Coutard frequently collaborates with researchers such as Étienne Decroly, Bruno Canard, Franck Touret, Xavier de Lamballerie, and Coralie Valle. This reflects a network of collaborations primarily concentrated in virology and molecular biology.

Their work is often published in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antiviral Research
  • Virologie
  • Journal of Virology
  • Molecules

Best Publications

  • The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade.

    B. Coutard;C. Valle;X. de Lamballerie;B. Canard

  • Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

    Michela Bollati;Karin Alvarez;René Assenberg;Cécile Baronti

  • In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication.

    Franck Touret;Magali Gilles;Karine Barral;Antoine Nougairède

  • Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

    Etienne Decroly;Claire Debarnot;François Ferron;Mickael Bouvet

  • A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

    Isabelle Imbert;Jean Claude Guillemot;Jean Marie Bourhis;Cécile Bussetta

  • Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity

    Etienne Decroly;Isabelle Imbert;Bruno Coutard;Mickaël Bouvet

  • The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

    Hélène Malet;Bruno Coutard;Saïd Jamal;Hélène Dutartre

  • Evidence for novel hepaciviruses in rodents.

    Jan Felix Drexler;Victor Max Corman;Marcel Alexander Müller;Alexander N. Lukashev

  • Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

    Ashleigh Shannon;Barbara Selisko;Nhung Thi Tuyet Le;Johanna Huchting

  • Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family

    Stefano Ricagno;Marie Pierre Egloff;Rachel Ulferts;Bruno Coutard

  • Recombinant protein expression and solubility screening in Escherichia coli: a comparative study

    Nick S. Berrow;K. Büssow;B. Coutard;J. Diprose

  • The N-terminal domain of the Arenavirus L protein is an RNA endonuclease essential in mRNA transcription

    Benjamin Morin;Bruno Coutard;Michaela Lelke;François Ferron

  • SARS-CoV ORF1b-encoded nonstructural proteins 12–16: Replicative enzymes as antiviral targets

    Lorenzo Subissi;Isabelle Imbert;François Ferron;Axelle Collet

  • Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.

    Rami Sommerstein;Rami Sommerstein;Lukas Roland Flatz;Mélissa Remy;Mélissa Remy;Pauline Malinge

  • Viral Macro Domains Reverse Protein ADP-Ribosylation

    Changqing Li;Yannick Debing;Gytis Jankevicius;Johan Neyts

  • Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.

    Bruno Coutard;Karine Barral;Julie Lichière;Barbara Selisko

  • 3C protease of enterovirus 68: Structure-based design of Michael acceptor inhibitors and their broad-spectrum antiviral effects against picornaviruses

    Jinzhi Tan;Shyla George;Yuri Kusov;Markus Perbandt

  • Understanding the alphaviruses: recent research on important emerging pathogens and progress towards their control.

    E. A. Gould;B. Coutard;H. Malet;B. Morin

  • Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen

    Marc Le Breton;Laurène Meyniel-Schicklin;Laurène Meyniel-Schicklin;Alexandre Deloire;Alexandre Deloire;Bruno Coutard

  • Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model

    Jean-Sélim Driouich;Maxime Cochin;Guillaume Lingas;Grégory Moureau

Frequent Co-Authors

Bruno Canard
Bruno Canard Aix-Marseille University
Etienne Decroly
Etienne Decroly Aix-Marseille University
Xavier de Lamballerie
Xavier de Lamballerie Aix-Marseille University
Johan Neyts
Johan Neyts Rega Institute for Medical Research
Rémi N. Charrel
Rémi N. Charrel Aix-Marseille University
Alexander E. Gorbalenya
Alexander E. Gorbalenya Leiden University
Ernest A. Gould
Ernest A. Gould Aix-Marseille University
Frank J. M. van Kuppeveld
Frank J. M. van Kuppeveld Utrecht University
Rolf Hilgenfeld
Rolf Hilgenfeld University of Lübeck
Pieter Leyssen
Pieter Leyssen Rega Institute for Medical Research

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