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Immunology

D-Index
61
Citations
9395
World Ranking
3279
National Ranking
1525

Research.com Recognitions

  • 2015 - Fellow of the American Society of Tropical Medicine and Hygiene (ASTMH)

Overview

Lynn Soong is a researcher affiliated with The University of Texas Medical Branch at Galveston in the United States. Their work spans several interconnected fields of study, primarily focusing on Immunology and Microbiology as well as Medicine. The subfields of their research include Parasitology, Immunology, Public Health, Environmental and Occupational Health, Infectious Diseases, and Molecular Biology.

Their research covers various topics with particular emphasis on vector-borne infectious diseases and mosquito-borne diseases and control. Additional topics they explore involve invertebrate immune response mechanisms, toxin mechanisms and immunotoxins, parasites and host interactions, leptospirosis research and findings, and immune response and inflammation.

Lynn Soong has published extensively in scientific journals. Frequent publication venues for their work include The Journal of Immunology, bioRxiv (Cold Spring Harbor Laboratory), PLoS neglected tropical diseases, Zoonoses, and Frontiers in Immunology.

  • Vector-borne infectious diseases
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Toxin Mechanisms and Immunotoxins
  • Parasites and Host Interactions
  • Leptospirosis research and findings
  • Immune Response and Inflammation

Their frequent co-authors include Yuejin Liang, Jiaren Sun, Casey Gonzales, James R. Fisher, and Galen Card, reflecting collaborations across diverse studies in their fields of expertise.

Notable recent papers by Lynn Soong include:

  • Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models (2022), published in Science Translational Medicine
  • Emerging and Re-emerging Zoonoses are Major and Global Challenges for Public Health (2021), published in Zoonoses
  • Epigenetic Suppression of HIV in Myeloid Cells by the BRD4-Selective Small Molecule Modulator ZL0580 (2020), published in Journal of Virology
  • Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection (2020), published in PLoS neglected tropical diseases
  • Neuroinflammation associated with scrub typhus and spotted fever group rickettsioses (2020), published in PLoS neglected tropical diseases

In recognition of professional contributions, Lynn Soong was awarded the title of Fellow of the American Society of Tropical Medicine and Hygiene (ASTMH) in 2015.

Best Publications

  • Disruption of CD40–CD40 Ligand Interactions Results in an Enhanced Susceptibility to Leishmania amazonensis Infection

    Lynn Soong;Jian Chao Xu;Iqbal S. Grewal;Peter Kima

  • Impaired Expression of Inflammatory Cytokines and Chemokines at Early Stages of Infection with Leishmania amazonensis

    Jiaxiang Ji;Jiaren Sun;Lynn Soong

  • Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection.

    L Soong;C H Chang;C H Chang;J Sun;B J Longley

  • L-arginine metabolism and its impact on host immunity against Leishmania infection

    Nanchaya Wanasen;Lynn Soong

  • Overproduction of TNF-α by CD8+ Type 1 Cells and Down-Regulation of IFN-γ Production by CD4+ Th1 Cells Contribute to Toxic Shock-Like Syndrome in an Animal Model of Fatal Monocytotropic Ehrlichiosis

    Nahed Ismail;Lynn Soong;Jere W. McBride;Gustavo Valbuena

  • Differential Induction of Interleukin-10 and Interleukin-12 in Dendritic Cells by Microbial Toll-Like Receptor Activators and Skewing of T-Cell Cytokine Profiles

    Hai Qi;Timothy L. Denning;Lynn Soong

  • Leishmania model for microbial virulence: the relevance of parasite multiplication and pathoantigenicity.

    Kwang Poo Chang;Steven G. Reed;Bradford S. McGwire;Bradford S. McGwire;Lynn Soong

  • CD4+CD25+ Regulatory T Cells Restrain Pathogenic Responses during Leishmania amazonensis Infection

    Jiaxiang Ji;Joseph Masterson;Jiaren Sun;Lynn Soong

  • Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models

    Unknown

  • Intradermal Infection Model for Pathogenesis and Vaccine Studies of Murine Visceral Leishmaniasis

    Saeed Ahmed;M. Colmenares;Lynn Soong;K. Goldsmith-Pestana

  • Aedes aegypti salivary gland extracts modulate anti-viral and TH1/TH2 cytokine responses to sindbis virus infection.

    Bradley S. Schneider;Lynn Soong;Nordin S. Zeidner;Stephen Higgs

  • Potentiation of West Nile encephalitis by mosquito feeding.

    Bradley S. Schneider;Lynn Soong;Yvette A. Girard;Gerald Campbell

  • Leishmania pifanoi amastigote antigens protect mice against cutaneous leishmaniasis.

    Lynn Soong;S. M. Duboise;P. Kima;D. Mcmahon-Pratt

  • Sand fly saliva enhances Leishmania amazonensis infection by modulating interleukin-10 production.

    Nilufer B. Norsworthy;Jiaren Sun;Dia Elnaiem;Gregory C Lanzaro

  • Leishmania amazonensis-Dendritic Cell Interactions In Vitro and the Priming of Parasite-Specific CD4+ T Cells In Vivo

    Hai Qi;Vsevolod Popov;Lynn Soong

  • Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis.

    Lynn Soong;Calvin A. Henard;Peter C. Melby

  • Enhanced Replication of Leishmania amazonensis Amastigotes in Gamma Interferon-Stimulated Murine Macrophages: Implications for the Pathogenesis of Cutaneous Leishmaniasis

    Hai Qi;Jiaxiang Ji;Nanchaya Wanasen;Lynn Soong

  • Modulation of dendritic cell function by Leishmania parasites.

    Lynn Soong

  • Distinct Roles for MyD88 and Toll-Like Receptor 2 during Leishmania braziliensis Infection in Mice

    Diego A. Vargas-Inchaustegui;Wendy Tai;Lijun Xin;Alison E. Hogg

  • mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production.

    Feidi Chen;Anthony Cao;Suxia Yao;Heather L. Evans-Marin

  • T-cell responsiveness of American cutaneous leishmaniasis Patients to purified Leishmania pifanoi amastigote antigens and Leishmania braziliensis promastigote antigens : Immunologic patterns associated with cure

    Sergio G. Coutinho;Marcia P. Oliveira;Alda M. Da-Cruz;Paula M. De Luca

Frequent Co-Authors

Diane McMahon-Pratt
Diane McMahon-Pratt Yale University
David H. Walker
David H. Walker The University of Texas Medical Branch at Galveston
Yingzi Cong
Yingzi Cong The University of Texas Medical Branch at Galveston
Vsevolod L. Popov
Vsevolod L. Popov The University of Texas Medical Branch at Galveston
Nancy H. Ruddle
Nancy H. Ruddle Yale University
Stephen Higgs
Stephen Higgs Kansas State University
Thomas G. Ksiazek
Thomas G. Ksiazek The University of Texas Medical Branch at Galveston
Peter C. Melby
Peter C. Melby The University of Texas Medical Branch at Galveston
Gregory C. Lanzaro
Gregory C. Lanzaro University of California, Davis
Alexander Bukreyev
Alexander Bukreyev The University of Texas Medical Branch at Galveston

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