What is he best known for?
The fields of study he is best known for:
Richard B. Pearson focuses on Molecular biology, Cancer research, PI3K/AKT/mTOR pathway, Cell biology and Protein kinase B.
His studies deal with areas such as HMGA2, Gene knockdown, Ribosome biogenesis, Phosphorylation and Transcription as well as Molecular biology.
Richard B. Pearson has researched Ribosome biogenesis in several fields, including RNA polymerase I, Transcription factor and P70-S6 Kinase 1.
His study in Phosphorylation is interdisciplinary in nature, drawing from both Cell and Peptide sequence.
His Cancer research research incorporates themes from Cancer and Mutant.
He interconnects Angiogenesis and PTEN in the investigation of issues within Protein kinase B.
His most cited work include:
- Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations. (878 citations)
- Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k (858 citations)
- Protein kinase recognition sequence motifs (855 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Cancer research, Cell biology, PI3K/AKT/mTOR pathway, Protein kinase B and Biochemistry.
Richard B. Pearson has researched Cancer research in several fields, including Ribosome biogenesis, Cancer, Ovarian cancer and Transcription.
While the research belongs to areas of Ribosome biogenesis, Richard B. Pearson spends his time largely on the problem of Molecular biology, intersecting his research to questions surrounding RNA polymerase I, Ribosomal protein, Cell and Mutant.
Regulation of gene expression is closely connected to Transcription factor in his research, which is encompassed under the umbrella topic of Cell biology.
His study in PI3K/AKT/mTOR pathway is interdisciplinary in nature, drawing from both Carcinogenesis and Cell growth.
His Phosphorylation study combines topics from a wide range of disciplines, such as P-type ATPase, Kinase and ATP7A.
He most often published in these fields:
- Cancer research (58.87%)
- Cell biology (43.72%)
- PI3K/AKT/mTOR pathway (37.23%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (58.87%)
- Gene (13.85%)
- Cancer (12.55%)
In recent papers he was focusing on the following fields of study:
Cancer research, Gene, Cancer, Transcription and Melanoma are his primary areas of study.
His studies deal with areas such as Translation, Ribosome biogenesis, Ovarian cancer and DNA damage as well as Cancer research.
His Translation research integrates issues from mTORC1, Protein kinase B and PI3K/AKT/mTOR pathway.
His biological study spans a wide range of topics, including Computational biology and Cell biology.
In general Transcription study, his work on RNA polymerase I often relates to the realm of Nucleolus, thereby connecting several areas of interest.
His research integrates issues of Oncogene, Cyclin-dependent kinase 6, Kinase and Cyclin-dependent kinase 4 in his study of Melanoma.
Between 2017 and 2021, his most popular works were:
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (328 citations)
- Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. (66 citations)
- First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study (40 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Cancer research, Gene, RNA polymerase I, Transcription and Cyclin-dependent kinase 4.
His studies in Cancer research integrate themes in fields like PARP inhibitor, DNA methylation, Cancer cell, Ovarian cancer and In vivo.
His Gene research includes themes of Network medicine, Systems biology and Cell type.
The RNA polymerase I study combines topics in areas such as Heterochromatin, Molecular biology, Genome instability and ATRX.
His Transcription research is multidisciplinary, incorporating elements of Toxicity, Anaplastic large-cell lymphoma, Adverse effect and Ribosome biogenesis.
The study incorporates disciplines such as Melanoma, Oncogene and Cyclin-dependent kinase 6 in addition to Cyclin-dependent kinase 4.
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