Richard B. Pearson

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Best Publications

• Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations.

  Richard B. Pearson;Bruce E. Kemp

  1292
  Citations

• Protein kinase recognition sequence motifs

  Bruce E. Kemp;Richard B. Pearson

  1270
  Citations

• Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k

  Harold B.J. Jefferies;Stefano Fumagalli;Patrick B. Dennis;Christoph Reinhard

  1207
  Citations

• Mutation of the PIK3CA gene in ovarian and breast cancer.

  Ian G. Campbell;Sarah E. Russell;David Y. H. Choong;Karen G. Montgomery

  1124
  Citations

• A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase.

  Heung-Chin Cheng;B. E. Kemp;R. B. Pearson;A. J. Smith

  700
  Citations

• The Akt kinase signals directly to endothelial nitric oxide synthase.

  B.J. Michell;J.E. Griffiths;K.I. Mitchelhill;I. Rodriguez-Crespo

  624
  Citations

• mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

  Katherine M. Hannan;Yves Brandenburger;Anna Jenkins;Kerith Sharkey

  597
  Citations

• Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.

  Megan J Bywater;Gretchen Poortinga;Gretchen Poortinga;Elaine Sanij;Elaine Sanij;Nadine Hein

  561
  Citations

• The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

  R. B. Pearson;P. B. Dennis;J.-W. Han;N. A. Williamson

  553
  Citations

• Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function.

  Katarzyna Jastrzebski;Katherine M. Hannan;Elissaveta B. Tchoubrieva;Ross D. Hannan

  315
  Citations

• The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence.

  B. E. Kemp;R. B. Pearson;V. Guerriero;Indrani C Bagchi

  294
  Citations

• Targeting PI3 Kinase/AKT/mTOR Signaling in Cancer

  Karen E Sheppard;Kathryn M Kinross;Benjamin Solomon;Richard B Pearson

  292
  Citations

• AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy

  Megan Astle;Katherine Hannan;Puiyee Ng;Rachel Lee

  290
  Citations

• Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

  R B Pearson;J R Woodgett;P Cohen;B E Kemp

  286
  Citations

• STIM1: a novel phosphoprotein located at the cell surface

  Shehnaaz S.M. Manji;Nigel J. Parker;Richard T. Williams;Leonie van Stekelenburg

  285
  Citations

• Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis

  Tiffany J. Parmenter;Margarete Kleinschmidt;Kathryn M. Kinross;Simon T. Bond

  277
  Citations

• Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis

  Charbel Darido;Smitha R. Georgy;Tomasz Wilanowski;Sebastian Dworkin

  268
  Citations

• Targeting the nucleolus for cancer intervention

  Jaclyn E Quin;Jaclyn E Quin;Jennifer R Devlin;Jennifer R Devlin;Donald Cameron;Katherine M Hannan;Katherine M Hannan

  254
  Citations

• Regulatory and structural motifs of chicken gizzard myosin light chain kinase

  Norma J. Olson;Richard B. Pearson;David S. Needleman;Mary Y. Hurwitz

  253
  Citations

• UBF levels determine the number of active ribosomal RNA genes in mammals.

  Elaine Sanij;Gretchen Poortinga;Kerith Sharkey;Sandy Hung

  243
  Citations