World's Best Scientists 2026 revealed!
Thomas Lecuit

Thomas Lecuit

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
16967
World Ranking
14794
National Ranking
577

Research.com Recognitions

  • 2014 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Thomas Lecuit is affiliated with the Collège de France in France and specializes in Biochemistry, Genetics and Molecular Biology, with a focus on Cellular Mechanics and Interactions. Their research spans multiple subfields including Cell Biology, Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Condensed Matter Physics, and Molecular Biology.

The scientist's research topics prominently include:

  • Cellular Mechanics and Interactions
  • Neurobiology and Insect Physiology Research
  • Biocrusts and Microbial Ecology
  • Micro and Nano Robotics
  • Physiological and biochemical adaptations
  • 3D Printing in Biomedical Research
  • Hippo pathway signaling and YAP/TAZ

Over the course of their career, Thomas Lecuit has collaborated frequently with:

  • Stefan Harmansa
  • Jean-Marc Philippe
  • Claudio Collinet
  • Anaïs Bailles
  • Emily W. Gehrels

The scientist's significant recent publications include:

  • "Programmed and self-organized flow of information during morphogenesis," 2021, Nature Reviews Molecular Cell Biology
  • "Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues," 2022, Annual Review of Cell and Developmental Biology
  • "Growth anisotropy of the extracellular matrix shapes a developing organ," 2023, Nature Communications
  • "Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry," 2021, Developmental Cell
  • "Curvature gradient drives polarized tissue flow in the Drosophila embryo," 2023, Proceedings of the National Academy of Sciences

Publication venues where Thomas Lecuit has appeared multiple times include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • L'annuaire du Collège de France
  • Nature Communications
  • Developmental Cell
  • Current Biology

The scientist has contributed to book publications, notably through Les conférences du Collège de France, including the inaugural lecture titled "The Dynamics of Living Systems: Inaugural lecture given on Thursday 27 April 2017," published in 2020.

Among honors received, Thomas Lecuit was named a Member of Academia Europaea in 2014 and is a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis.

    Thomas Lecuit;Pierre-François Lenne

  • Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation

    Claire Bertet;Lawrence Sulak;Thomas Lecuit

  • Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing.

    Thomas Lecuit;William J. Brook;Medard Ng;Manuel Calleja

  • Planar polarized actomyosin contractile flows control epithelial junction remodelling

    Matteo Rauzi;Pierre-François Lenne;Thomas Lecuit

  • Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis.

    Matteo Rauzi;Pascale Verant;Thomas Lecuit;Pierre-François Lenne

  • Mechanics of epithelial tissue homeostasis and morphogenesis.

    Charlène Guillot;Thomas Lecuit

  • Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis

    Thomas Lecuit;Pierre-François Lenne;Edwin Munro

  • E-cadherin junctions as active mechanical integrators in tissue dynamics

    Thomas Lecuit;Alpha S. Yap

  • A two-tiered mechanism for stabilization and immobilization of E-cadherin

    Matthieu Cavey;Matteo Rauzi;Matteo Rauzi;Pierre-François Lenne;Thomas Lecuit

  • Cooperative dimerization of paired class homeo domains on DNA.

    D. Wilson;Guojun Sheng;T. Lecuit;N. Dostatni

  • Proximal-distal axis formation in the Drosophila leg.

    Thomas Lecuit;Stephen M. Cohen

  • A self-organized biomechanical network drives shape changes during tissue morphogenesis

    Akankshi Munjal;Jean-Marc Philippe;Edwin Munro;Thomas Lecuit

  • Biomechanical regulation of contractility: spatial control and dynamics.

    Romain Levayer;Thomas Lecuit

  • Local and tissue-scale forces drive oriented junction growth during tissue extension

    Claudio Collinet;Matteo Rauzi;Pierre-François Lenne;Thomas Lecuit

  • Molecular Bases of Cell–Cell Junctions Stability and Dynamics

    Matthieu Cavey;Thomas Lecuit

  • Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye

    Volker Wiersdorff;Thomas Lecuit;Stephen M. Cohen;Marek Mlodzik

  • Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis.

    Romain Levayer;Anne Pelissier-Monier;Thomas Lecuit

  • A global pattern of mechanical stress polarizes cell divisions and cell shape in the growing Drosophila wing disc.

    Loïc LeGoff;Hervé Rouault;Thomas Lecuit

  • Polarized Insertion of New Membrane from a Cytoplasmic Reservoir during Cleavage of the Drosophila Embryo

    Thomas Lecuit;Eric Francis Wieschaus

  • Orchestrating size and shape during morphogenesis

    Thomas Lecuit;Loïc Le Goff

Frequent Co-Authors

Stephen M. Cohen
Stephen M. Cohen University of Copenhagen
Eric Wieschaus
Eric Wieschaus Princeton University
Satyajit Mayor
Satyajit Mayor National Centre for Biological Sciences
Denis Thieffry
Denis Thieffry École Normale Supérieure
Claude Desplan
Claude Desplan New York University
Jacques van Helden
Jacques van Helden Aix-Marseille University
Juan Modolell
Juan Modolell Spanish National Research Council
Martin Beck
Martin Beck TU Dresden
Eileen E. M. Furlong
Eileen E. M. Furlong European Bioinformatics Institute
Gijsje H. Koenderink
Gijsje H. Koenderink Delft University of Technology

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