2026 Philip C. Wong: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	79	4224	3898	2068	1866	208	30542

Research.com Recognitions

2007 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

Overview

Philip C. Wong is affiliated with Johns Hopkins University School of Medicine in the United States. Their primary field of study is Medicine, with a more focused involvement in subfields such as Neurology, Molecular Biology, Genetics, Physiology, and Epidemiology.

The main topics of research covered in their work include:

Amyotrophic Lateral Sclerosis Research
Neurogenetic and Muscular Disorders Research
Alzheimer's disease research and treatments
Neuroinflammation and Neurodegeneration Mechanisms
Prion Diseases and Protein Misfolding
RNA Research and Splicing
Inflammatory Myopathies and Dermatomyositis

Recent papers published by Philip C. Wong include:

A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD (2024, Nature Medicine)
Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis (2022, Science Translational Medicine)
Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease (2022, Journal of Biological Chemistry)
Fluid biomarkers for amyotrophic lateral sclerosis: a review (2024, Molecular Neurodegeneration)
Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline (2023, Acta Neuropathologica)

Frequent co-authors collaborating with Philip C. Wong are:

Jonathan P. Ling
Irika R. Sinha
Katherine E. Irwin
Juan C. Troncoso
Kerstin E. Braunstein

The research has been disseminated in several key publication venues, including:

bioRxiv (Cold Spring Harbor Laboratory)
Alzheimer s & Dementia
Molecular Neurodegeneration
Advanced Science
Nature Medicine

Philip C. Wong received the Metlife Foundation Award for Medical Research in Alzheimer's Disease in 2007.

Best Publications

Amyloid Precursor Protein Processing and Alzheimer's Disease

Richard J. O'Brien;Philip C. Wong

2197
Citations
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Philip C Wong;Carlos A Pardo;David R Borchelt;Michael K Lee

1744
Citations
BACE1 is the major beta-secretase for generation of Abeta peptides by neurons.

Huaibin Cai;Yanshu Wang;Diane McCarthy;Hongjin Wen

1607
Citations
Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

Philip C. Wong;Hui Zheng;Hua Chen;Mark W. Becher

917
Citations
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

Brian D. Freibaum;Yubing Lu;Rodrigo Lopez-Gonzalez;Nam Chul Kim

903
Citations
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease.

Li Bang Yang;Kristina Lindholm;Riqiang Yan;Martin Citron

899
Citations
An Overview of APP Processing Enzymes and Products

Vivian W. Chow;Mark P. Mattson;Philip C. Wong;Marc Gleichmann

823
Citations
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

David R. Borchelt;Michael K. Lee;Hilda S. Slunt;Michael Guarnieri

804
Citations
Bace1 modulates myelination in the central and peripheral nervous system

Xiangyou Hu;Caitlin W Hicks;Wanxia He;Philip Wong

747
Citations
The β-Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

Robert Vassar;Dora M. Kovacs;Riqiang Yan;Philip C. Wong

694
Citations
BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions

Fiona M. Laird;Huaibin Cai;Alena V. Savonenko;Mohamed H. Farah

674
Citations
Toxicity of Familial ALS-Linked SOD1 Mutants from Selective Recruitment to Spinal Mitochondria

Jian Liu;Concepción Lillo;P.Andreas Jonsson;Christine Vande Velde

646
Citations
Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients

Rena Li;Kristina Lindholm;Li-Bang Yang;Xu Yue

644
Citations
Association of γ-Secretase with Lipid Rafts in Post-Golgi and Endosome Membranes

Kulandaivelu S. Vetrivel;Haipeng Cheng;William Lin;Takashi Sakurai

527
Citations
Histological Evidence of Protein Aggregation in Mutant SOD1 Transgenic Mice and in Amyotrophic Lateral Sclerosis Neural Tissues

Mitsunori Watanabe;Margaret Dykes-Hoberg;Valeria Cizewski Culotta;Donald L. Price

516
Citations
Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica

Alga Zuccaro;Urs Lahrmann;Ulrich Güldener;Gregor Langen

504
Citations
Neurofilaments are obligate heteropolymers in vivo

Michael K. Lee;Zuoshang Xu;Philip C. Wong;Don W. Cleveland

473
Citations
Effects of PS1 Deficiency on Membrane Protein Trafficking in Neurons

Satoshi Naruse;Gopal Thinakaran;Jin Jun Luo;John W. Kusiak

468
Citations
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice

Xiu Shan;Po Min Chiang;Donald L. Price;Philip C. Wong

422
Citations
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells.

Shahrooz Rabizadeh;Edith Butler Gralla;David R. Borchelt;Ryder Gwinn

421
Citations