World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
56
Citations
12367
World Ranking
14345
National Ranking
6042

Overview

James McSwiggen is an independent scientist and consultant based in the United States with research contributions primarily in medicine, agricultural and biological sciences, and biochemistry, genetics, and molecular biology.

Their work has been published in the Journal of Biosciences and Medicines, a venue in which they have multiple contributions. The scientist has collaborated frequently with Anya Vaish, reflecting a joint focus on their shared research interests.

Main areas of study for McSwiggen include infectious diseases, animal science and zoology, and molecular biology. These subfields support their broader work within the following key topics:

  • SARS-CoV-2 and COVID-19 research
  • Animal virus infections studies
  • Vaccines and immunoinformatics approaches

One of their recent published papers is titled "Bioinformatic Analysis of SARS-CoV-2 Genomes to Develop a Universal Coronavirus Vaccine," which appeared in 2022 in the Journal of Biosciences and Medicines. This paper engages with computational approaches to vaccine design by analyzing viral genomic data.

The research profile indicates a focus on viral pathogens affecting both humans and animals, alongside methodological applications in bioinformatics and immunology. Their contributions target emerging infectious disease challenges through multidisciplinary approaches involving molecular biology and animal sciences.

Best Publications

  • RNA interference mediated inhibition of adenosine A1 receptor (ADORA1) gene expression using short interfering RNA

    Kathy Fosnaugh;James McSwiggen

  • RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)

    James McSwiggen;Bharat Chowrira;Leonid Beigelman;Dennis Macejak

  • Method and reagent for inhibiting viral replication.

    Kenneth G. Draper;Lech W. Dudycz;James A. Mcswiggen;Dennis G. Macejak

  • Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

    David V. Morrissey;Karin Blanchard;Lucinda Shaw;Kristi Jensen

  • RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)

    James McSwiggen;Leonid Beigelman;Pamela Pavco

  • RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid

    James Mcswiggen;Leonid Beigelman;Dennis Macejak;Shawn Zinnen

  • RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)

    James Mcswiggen;Leonid Beigelman;Bharat Chowrira;Pamela Pavco

  • RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)

    James McSwiggen;Leonid Beigelman

  • Nucleic acid molecules with novel chemical compositions capable of modulating gene expression

    James D. Thompson;Leonid Beigelman;James A. Mcswiggen;Alexander Karpeisky

  • Chemical Modification of Hammerhead Ribozymes: CATALYTIC ACTIVITY AND NUCLEASE RESISTANCE

    Leonid Beigelman;James A. McSwiggen;Kenneth G. Draper;Carolyn Gonzalez

  • Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters.

    S C Kowalczykowski;L S Paul;N Lonberg;J W Newport

  • RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)

    James McSwiggen;Leonid Beigelman

  • RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)

    James Mcswiggen;Pamela Pavco;Leonid Beigelman;Kathy Fosnaugh

  • Rna interference mediated inhibition of hepatitis c virus (hcv) gene expression using short interfering nucleic acid (sina)

    James Mcswiggen;Leonid Beigelman;Dennis Macejak;David Morrissey

  • RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)

    James McSwiggen;Leonid Beigelman

  • RNA interference mediated inhibition of MAP kinase gene expression using short interfering nucleic acid (siNA)

    James McSwiggen;Bharat Chowrira;Peter Haeberli;Leonid Beigelman

  • HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes.

    Ratan K. Maitra;Nigel A.J. McMillan;Shailesh Desai;James McSwiggen

  • Enzymatic nucleic acid treatment of diseases or conditions related to levels of IKK-gamma and PKR

    James McSwiggen

  • In vitro and in vivo comparison of hammerhead, hairpin, and hepatitis delta virus self-processing ribozyme cassettes.

    B M Chowrira;P A Pavco;J A McSwiggen

  • RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)

    James McSwiggen

Frequent Co-Authors

Leonid Beigelman
Leonid Beigelman Johnson & Johnson
Robert H. Silverman
Robert H. Silverman Kent State University
Ganes C. Sen
Ganes C. Sen Case Western Reserve University
Ara G. Hovanessian
Ara G. Hovanessian Centre national de la recherche scientifique, CNRS
Bryan R.G. Williams
Bryan R.G. Williams Monash University
John D. Morrey
John D. Morrey Utah State University

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