World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
26722
World Ranking
13507
National Ranking
5728

Kallanthottathil G. Rajeev publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Kallanthottathil G. Rajeev sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 107 publications — 7th percentile

7% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Kallanthottathil G. Rajeev D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Kallanthottathil G. Rajeev sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Kallanthottathil G. Rajeev is a researcher affiliated with Alnylam Pharmaceuticals in the United States. Their work spans several areas within biochemistry, genetics, and molecular biology, with a focus on molecular biology and related subfields including rheumatology, public health, cardiovascular medicine, and immunology.

Their research topics comprise RNA interference and gene delivery, CRISPR and genetic engineering, DNA and nucleic acid chemistry, advanced biosensing and bioanalysis techniques, systemic lupus erythematosus research, RNA and protein synthesis mechanisms, and mosquito-borne diseases and control.

Rajeev has contributed to multiple research publications across notable scientific journals. Frequent publication venues include:

  • Journal of Medicinal Chemistry
  • Nature
  • Nature Communications
  • Nucleic Acids Research
  • Journal of the American Chemical Society

Recent papers authored or co-authored by Rajeev include:

  • In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates, 2021, Nature
  • GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy, 2023, Nature Communications
  • Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo, 2021, Nucleic Acids Research
  • Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs, 2023, Journal of the American Chemical Society
  • Metabolically Stable Anomeric Linkages Containing GalNAc-siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways, 2023, Journal of Medicinal Chemistry

Their frequent co-authors include:

  • Muthiah Manoharan
  • Klaus Charissé
  • Martin Egli
  • Kiran Musunuru
  • Alexandra C. Chadwick

Rajeev's research interest is deeply rooted in the study of RNA interference and gene delivery mechanisms, contributing to advancements in CRISPR-based genetic engineering. Their work also explores nucleic acid chemistry modifications that improve the pharmacological profiles and stability of therapeutic molecules.

They have engaged in investigation related to systemic lupus erythematosus and have contributed knowledge pertinent to RNA and protein synthesis mechanisms. Additionally, their research touches on public health topics such as mosquito-borne diseases and control, illustrating a broad interdisciplinary approach to molecular biology and medicine.

Best Publications

  • Silencing of microRNAs in vivo with ‘antagomirs’

    Jan Krützfeldt;Nikolaus Rajewsky;Ravi Braich;Kallanthottathil G. Rajeev

  • Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

    Jürgen Soutschek;Akin Akinc;Birgit Bramlage;Klaus Charisse

  • Rational design of cationic lipids for siRNA delivery

    Sean C Semple;Akin Akinc;Jianxin Chen;Ammen P Sandhu

  • A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

    Akin Akinc;Andreas Zumbuehl;Andreas Zumbuehl;Michael Goldberg;Elizaveta S Leshchiner

  • Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

    Muthusamy Jayaraman;Steven M. Ansell;Barbara L. Mui;Ying K. Tam

  • Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.

    Akin Akinc;William Querbes;Soma De;June Qin

  • Mechanisms and optimization of in vivo delivery of lipophilic siRNAs

    Christian Wolfrum;Shuanping Shi;K Narayanannair Jayaprakash;Muthusamy Jayaraman

  • Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

    Jayaprakash K. Nair;Jennifer L. S. Willoughby;Amy Chan;Klaus Charisse

  • Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

    Maria Frank-Kamenetsky;Aldo Grefhorst;Norma N. Anderson;Timothy S. Racie

  • Specificity, duplex degradation and subcellular localization of antagomirs

    Jan Krützfeldt;Satoru Kuwajima;Ravi Braich;Kallanthottathil G. Rajeev

  • In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.

    Kiran Musunuru;Alexandra C. Chadwick;Taiji Mizoguchi;Sara P. Garcia

  • Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

    Martin A Maier;Muthusamy Jayaraman;Shigeo Matsuda;Ju Liu

  • Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

    Marian DiFiglia;Miguel Sena-Esteves;Kathryn O. Chase;Ellen Sapp

  • Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

    Akin Akinc;Michael Goldberg;June Qin;J Robert Dorkin

  • Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles

    Barbara L Mui;Ying K Tam;Muthusamy Jayaraman;Steven M Ansell

  • An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia

    Alfica Sehgal;Scott Barros;Lacramioara Ivanciu;Brian Cooley

  • siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes

    Shigeo Matsuda;Kristofer Keiser;Jayaprakash K. Nair;Klaus Charisse

  • Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates

    Donald J. Foster;Christopher R. Brown;Sarfraz Shaikh;Casey Trapp

  • Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates.

    Jayaprakash K. Nair;Husain Attarwala;Alfica Sehgal;Qianfan Wang

  • Chemically modified oligonucleotides

    Muthiah Manoharan;Venkitasamy Kesavan;Kallanthottathil G. Rajeev

Frequent Co-Authors

Muthiah Manoharan
Muthiah Manoharan Alnylam Pharmaceuticals (United States)
Martin Maier
Martin Maier Alnylam Pharmaceuticals (United States)
Martin Egli
Martin Egli Vanderbilt University
Michael J. Hope
Michael J. Hope University of British Columbia
Pieter R. Cullis
Pieter R. Cullis University of British Columbia
Victor Koteliansky
Victor Koteliansky Skolkovo Institute of Science and Technology
Antonin de Fougerolles
Antonin de Fougerolles Alnylam Pharmaceuticals (United States)
Markus Stoffel
Markus Stoffel University of Geneva
Marco A. Ciufolini
Marco A. Ciufolini University of British Columbia

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