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Andrea Rasola

Andrea Rasola

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
8539
World Ranking
18372
National Ranking
588

Overview

Andrea Rasola is affiliated with the University of Padua in Italy and has a research portfolio spanning biochemistry, genetics, molecular biology, and medicine. Their work has contributed extensively to understanding molecular and cellular processes, especially in relation to cancer biology and mitochondrial function.

The scientist's research concentrates on several key areas including:

  • ATP Synthase and ATPases Research
  • Heat Shock Proteins Research
  • Mitochondrial Function and Pathology
  • Cancer, Hypoxia, and Metabolism
  • Signaling Pathways in Disease
  • Endoplasmic Reticulum Stress and Disease
  • SARS-CoV-2 and COVID-19 Research

Their publications have appeared frequently in high-impact venues with a particular focus on biochemistry and cell biology. The prominent journals and platforms where they have published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Death and Disease
  • Cells
  • Cell Death and Differentiation
  • Journal of Chemical Information and Modeling

Their most cited recent papers include the following notable works:

  • "Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters," 2021, International Journal of Molecular Sciences
  • "Hexokinase 2 displacement from mitochondria-associated membranes prompts Ca 2+ -dependent death of cancer cells," 2020, EMBO Reports
  • "Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase," 2021, Nature Communications
  • "Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1," 2020, Cell Reports
  • "Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming," 2020, Journal of Hepatology

Andrea Rasola collaborates extensively with other researchers, including frequent co-authorship with:

  • Giorgio Colombo
  • Ionica Masgras
  • Elisabetta Moroni
  • Francesco Ciscato
  • Claudio Laquatra

Their studies bridge molecular mechanisms at the cellular level with pathological states, particularly in cancer research and mitochondrial diseases. Rasola's work often involves dissecting complex processes such as mitochondrial permeability transitions, protein chaperoning, and metabolic reprogramming in disease contexts.

Best Publications

  • Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis

    Andrea Rasola;Paolo Bernardi

  • The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis

    Andrea Rasola;Paolo Bernardi

  • The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

    Paolo Bernardi;Andrea Rasola;Andrea Rasola;Andrea Rasola;Michael Forte;Giovanna Lippe;Giovanna Lippe;Giovanna Lippe

  • Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels

    Federica Chiara;Diego Castellaro;Oriano Marin;Valeria Petronilli

  • Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

    Anna Pastò;Chiara Bellio;Giorgia Pilotto;Vincenzo Ciminale

  • Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

    Andrea Rasola;Marco Sciacovelli;Federica Chiara;Boris Pantic

  • The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase

    Marco Sciacovelli;Giulia Guzzo;Virginia Morello;Christian Frezza

  • Calcium and Cell Death: The Mitochondrial Connection

    P Bernardi;A Rasola

  • Signal transduction to the permeability transition pore.

    Andrea Rasola;Marco Sciacovelli;Boris Pantic;Paolo Bernardi

  • Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

    Jingjing Chen;Jingjing Chen;Ilaria Guccini;Diletta Di Mitri;Daniela Brina

  • Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury

    Xiaoyang Wang;Ylva Carlsson;Emy Basso;Changlian Zhu;Changlian Zhu

  • Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters

    Francesco Ciscato;Lavinia Ferrone;Ionica Masgras;Ionica Masgras;Claudio Laquatra

  • A positive feedback loop between hepatocyte growth factor receptor and beta-catenin sustains colorectal cancer cell invasive growth.

    Andrea Rasola;Andrea Rasola;M Fassetta;F De Bacco;L D'alessandro

  • A flow cytometry assay simultaneously detects independent apoptotic parameters

    Andrea Rasola;Massimo Geuna

  • Apoptosis enhancement by the HIV-1 Nef protein.

    Andrea Rasola;Daniela Gramaglia;Carla Boccaccio;Paolo M. Comoglio

  • Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells

    Andrea Rasola;Len Neckers;Didier Picard

  • The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells.

    Ionica Masgras;Carlos Sanchez-Martin;Giorgio Colombo;Andrea Rasola

  • Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death.

    Daniela Catanzaro;Edoardo Gaude;Genny Orso;Carla Giordano

  • The mitochondrial permeability transition pore and its adaptive responses in tumor cells.

    Andrea Rasola;Paolo Bernardi

  • Cholesterol Loss Enhances TrkB Signaling in Hippocampal Neurons Aging in Vitro

    Mauricio G. Martin;Simona Perga;Laura Trovò;Andrea Rasola

Frequent Co-Authors

Paolo Bernardi
Paolo Bernardi University of Padua
Oriano Marin
Oriano Marin University of Padua
Luis J. V. Galietta
Luis J. V. Galietta Telethon Institute Of Genetics And Medicine
Paola Chiarugi
Paola Chiarugi University of Florence
Francesco Argenton
Francesco Argenton University of Padua
Amedeo Columbano
Amedeo Columbano University of Cagliari
Silvia Giordano
Silvia Giordano University of Turin
Christian Frezza
Christian Frezza University of Cambridge
Michael Forte
Michael Forte Oregon Health & Science University
Giovanni Romeo
Giovanni Romeo University of Bologna

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