World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14236
World Ranking
13047
National Ranking
95

Overview

Johan Peränen is affiliated with the University of Helsinki in Finland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with specific contributions in Cell Biology, Oncology, Molecular Biology, Immunology and Allergy, and Cancer Research.

The scientist's main topics of work include:

  • Cellular Mechanics and Interactions
  • Skin and Cellular Biology Research
  • Cell Adhesion Molecules Research
  • Cancer, Lipids, and Metabolism
  • Pancreatic and Hepatic Oncology Research
  • Caveolin-1 and cellular processes
  • Lysosomal Storage Disorders Research

Johan Peränen has published research articles in various well-known academic venues, including:

  • Nature Communications
  • Cancer Research
  • Traffic
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The EMBO Journal

Recent papers authored or co-authored by Johan Peränen include:

  • "Focal adhesions contain three specialized actin nanoscale layers," 2024, Nature Communications
  • "High-content imaging and structure-based predictions reveal functional differences between Niemann-Pick C1 variants," 2020, Traffic
  • "Lipid Metabolic Reprogramming Extends beyond Histologic Tumor Demarcations in Operable Human Pancreatic Cancer," 2022, Cancer Research
  • "Specialized actin nanoscale layers control focal adhesion turnover," 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • "Spatially targeted chemokine exocytosis guides transmigration at lymphatic endothelial multicellular junctions," 2024, The EMBO Journal

Their frequent collaborators include Pekka Lappalainen, Reena Kumari, Katharina Ven, Megan Chastney, and Jesse Aaron, with multiple joint publications.

Best Publications

  • A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis

    Maxence V. Nachury;Alexander V. Loktev;Qihong Zhang;Christopher J. Westlake

  • VIP21/CAVEOLIN IS A CHOLESTEROL-BINDING PROTEIN

    Masayuki Murata;Johan Peranen;Rupert Schreiner;Felix Wieland

  • A molecular network for de novo generation of the apical surface and lumen

    David M. Bryant;Anirban Datta;Alejo E. Rodríguez-Fraticelli;Johan Peränen

  • N-glycans as apical sorting signals in epithelial cells

    Peter Scheiffele;Johan Peränen;Kai Simons

  • AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain.

    Cristinel P. Mîinea;Hiroyuki Sano;Susan Kane;Eiko Sano

  • Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

    Päivi Lindholm;Merja H. Voutilainen;Juha Laurén;Juha Laurén;Johan Peränen

  • Coordination of Rab8 and Rab11 in primary ciliogenesis

    Andreas Knödler;Shanshan Feng;Jian Zhang;Xiaoyu Zhang

  • T7 vectors with modified T7lac promoter for expression of proteins in Escherichia coli

    Johan Peränen;Marja Rikkonen;Marko Hyvönen;Leevi Kääriäinen

  • Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease

    Merja H Voutilainen;Susanne Bäck;Eeva Pörsti;Liisa Toppinen

  • CP110 Suppresses Primary Cilia Formation through Its Interaction with CEP290, a Protein Deficient in Human Ciliary Disease

    William Y. Tsang;Carine Bossard;Hemant Khanna;Johan Peränen

  • Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts.

    Johan Peränen;Petri Auvinen;Hilkka Virta;Roger Wepf

  • Mutant rab8 Impairs docking and fusion of rhodopsin-bearing post-Golgi membranes and causes cell death of transgenic Xenopus rods.

    Orson L. Moritz;Beatrice M. Tam;Larry L. Hurd;Johan Peränen

  • FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis.

    Katarina Hattula;Johan Peränen

  • Characterization of the Rab8-specific membrane traffic route linked to protrusion formation

    Katarina Hattula;Johanna Furuhjelm;Jaana Tikkanen;Kimmo Tanhuanpää

  • A Rab8-specific GDP/GTP Exchange Factor Is Involved in Actin Remodeling and Polarized Membrane Transport

    Katarina Hattula;Johanna Furuhjelm;Airi Arffman;Johan Peränen

  • Myosin Vb Interacts with Rab8a on a Tubular Network Containing EHD1 and EHD3

    Joseph T. Roland;Anne K. Kenworthy;Johan Peranen;Steve Caplan

  • MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain.

    Päivi Lindholm;Johan Peränen;Jaan-Olle Andressoo;Nisse Kalkkinen

  • Rab6, Rab8, and MICAL3 Cooperate in Controlling Docking and Fusion of Exocytotic Carriers

    Ilya Grigoriev;Ka Lou Yu;Emma Martinez-Sanchez;Andrea Serra-Marques

  • ATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2.

    M Rikkonen;J Peränen;L Kääriäinen

  • Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA.

    Yaming Jiu;Johan Peränen;Niccole Schaible;Fang Cheng

Frequent Co-Authors

Mart Saarma
Mart Saarma University of Helsinki
Leevi Kääriäinen
Leevi Kääriäinen University of Helsinki
Elina Ikonen
Elina Ikonen University of Helsinki
Mikko Airavaara
Mikko Airavaara University of Helsinki
Nisse Kalkkinen
Nisse Kalkkinen University of Helsinki
Vesa M. Olkkonen
Vesa M. Olkkonen University of Helsinki
Pekka Lappalainen
Pekka Lappalainen University of Helsinki
Kai Simons
Kai Simons Lipotype
Yun Wang
Yun Wang National Health Research Institutes
Wei Guo
Wei Guo University of Pennsylvania

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