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Johan Frostegård

Johan Frostegård

D-Index & Metrics

Immunology

D-Index
70
Citations
16122
World Ranking
2434
National Ranking
48

Overview

Johan Frostegård is affiliated with the Karolinska Institute in Sweden. Their research primarily focuses on immunology, rheumatology, and cardiovascular medicine, with a significant emphasis on systemic lupus erythematosus (SLE), atherosclerosis, and related cardiovascular diseases.

The scientist's recent publications cover topics at the intersection of autoimmune diseases and cardiovascular health. Key papers include:

  • Systemic lupus erythematosus and cardiovascular disease, 2022, Journal of Internal Medicine
  • Patients with SLE have higher risk of cardiovascular events and mortality in comparison with controls with the same levels of traditional risk factors and intima-media measures, which is related to accumulated disease damage and antiphospholipid syndrome: a case-control study over 10 years, 2021, Lupus Science & Medicine
  • The role of PCSK9 in inflammation, immunity, and autoimmune diseases, 2021, Expert Review of Clinical Immunology
  • Similar progression of carotid intima-media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients, 2020, Lupus Science & Medicine
  • Proprotein convertase subtilisin kexin 9 is associated with disease activity and is implicated in immune activation in systemic lupus erythematosus, 2020, Lupus

The frequent coauthors collaborating with Johan Frostegård include:

  • Sofia Ajeganova
  • Ingiäld Hafström
  • Mizanur Rahman
  • Divya Thiagarajan
  • Shailesh Kumar Samal

Publications by Frostegård have appeared predominantly in the following venues:

  • Annals of the Rheumatic Diseases
  • Scientific Reports
  • European Heart Journal
  • Journal of Internal Medicine
  • Lupus Science & Medicine

In terms of fields of study, the research is distributed mainly between:

  • Medicine
  • Immunology and Microbiology

Subfields of interest include:

  • Immunology
  • Rheumatology
  • Radiology, Nuclear Medicine and Imaging
  • Cardiology and Cardiovascular Medicine
  • Surgery

The core research topics explored encompass:

  • Atherosclerosis and Cardiovascular Diseases
  • Systemic Lupus Erythematosus Research
  • Monoclonal and Polyclonal Antibodies Research
  • Lipoproteins and Cardiovascular Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Diabetes and associated disorders

Best Publications

  • Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines.

    Johan Frostegård;Ann-Kristin Ulfgren;Pernilla Nyberg;Ulf Hedin

  • Immunity, atherosclerosis and cardiovascular disease

    Johan Frostegård

  • Risk Factors for Cardiovascular Disease in Systemic Lupus Erythematosus

    E Svenungsson;K Jensen-Urstad;M Heimbürger;A Silveira

  • Risk factors for cardiovascular disease in patients with periodontitis

    Kåre Buhlin;Anders Gustafsson;A.Graham Pockley;Johan Frostegård

  • Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937.

    Johan Frostegard;Jan Nilsson;Anders Haegerstrand;Anders Hamsten

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations.

    Johan Frostegård;Elisabet Svenungsson;Ruihua Wu;Iva Gunnarsson

  • Circulating heat shock protein 60 is associated with early cardiovascular disease.

    A. Graham Pockley;Ruhia Wu;Carola Lemne;Rolf Kiessling

  • Atherosclerosis in Patients With Autoimmune Disorders

    Johan Frostegård

  • Induction of T-cell activation by oxidized low density lipoprotein.

    Johan Frostegard;Ruihua Wu;Ricardo Giscombe;Goran Holm

  • Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension

    Alan G. Pockley;Anastasia Georgiades;Thomas Thulin;Ulf de Faire

  • Biologically modified LDL increases the adhesive properties of endothelial cells.

    Johan Frostegard;Anders Haegerstrand;Magnus Gidlund;Jan Nilsson

  • Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism.

    Y H Huang;L Schäfer-Elinder;R Wu;H E Claesson

  • Circulating heat shock protein and heat shock protein antibody levels in established hypertension.

    A. Pockley;Ulf De Faire;Rolf Kiessling;Carola Lemne

  • Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction.

    Kristina Edfeldt;Anna M Bennet;Per Eriksson;Johan Frostegård

  • Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor alpha/tumor necrosis factor receptor system in systemic lupus erythematosus.

    Elisabet Svenungsson;Iva Gunnarsson;Guo-Zhong Fei;Ingrid E Lundberg

  • Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension

    Jun Su;Anastasia Georgiades;Ruihua Wu;Thomas Thulin

  • TNF-α: a link between hypertriglyceridaemia and inflammation in SLE patients with cardiovascular disease

    E Svenungsson;G Z Fei;K Jensen-Urstad;U de Faire

  • Autoantibodies to OxLDL Are Decreased in Individuals With Borderline Hypertension

    R Wu;U de Faire;C Lemne;J L Witztum

  • SLE, atherosclerosis and cardiovascular disease.

    Frostegård J

Frequent Co-Authors

Ulf de Faire
Ulf de Faire Karolinska Institute
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Elisabet Svenungsson
Elisabet Svenungsson Karolinska University Hospital
Anders Hamsten
Anders Hamsten Karolinska Institute
Torsten Witte
Torsten Witte Hannover Medical School
Lennart Truedsson
Lennart Truedsson Lund University
Hans Grönlund
Hans Grönlund Karolinska Institute
Yehuda Shoenfeld
Yehuda Shoenfeld Sheba Medical Center
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
Sandra D'Alfonso
Sandra D'Alfonso University of Eastern Piedmont Amadeo Avogadro

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