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Gregg J. Silverman

Gregg J. Silverman

D-Index & Metrics

Immunology

D-Index
66
Citations
17391
World Ranking
2743
National Ranking
1308

Overview

Gregg J. Silverman is affiliated with New York University in the United States. Their research primarily spans the field of Medicine, with a focus on Immunology, Infectious Diseases, Molecular Biology, Rheumatology, and Pathology and Forensic Medicine. The scientist's work addresses a range of topics including gut microbiota and health, systemic lupus erythematosus research, multiple sclerosis research studies, Clostridium difficile and Clostridium perfringens research, SARS-CoV-2 and COVID-19 research, immune cell function and interaction, and T-cell and B-cell immunology.

Silverman has published extensively, with contributions appearing frequently in several key venues. These include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Abstracts, Annals of the Rheumatic Diseases, and Annals of Clinical and Translational Neurology.

Their recent notable papers include the following:

  • "Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus," 2021, The Journal of Experimental Medicine
  • "Blood clots and TAM receptor signalling in COVID-19 pathogenesis," 2020, Nature Reviews. Immunology
  • "Sex-dependent Lupus Blautia (Ruminococcus) gnavus strain induction of zonulin-mediated intestinal permeability and autoimmunity," 2022, Frontiers in Immunology
  • "Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares," 2023, Annals of the Rheumatic Diseases
  • "Lupus gut microbiota transplants cause autoimmunity and inflammation," 2021, Clinical Immunology

Collaborative relationships are a consistent part of Silverman's research with frequent co-authors including Ilya Kister, Doua F. Azzouz, Abhimanyu Amarnani, Y. Patskovsky, and Yogambigai Velmurugu, each with multiple shared publications.

The scientist's body of work advances understanding in various immunological disorders, especially systemic lupus erythematosus, and the interactions between gut microbiota and autoimmune processes. Moreover, their studies contribute to the broader investigation of immune cell functions and infectious diseases, including COVID-19 pathogenesis.

Best Publications

  • Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

    Yukio Sato;Mark Roman;Helen Tighe;Delphine Lee

  • Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL.

    Christoph J Binder;Sohvi Hörkkö;Sohvi Hörkkö;Asheesh Dewan;Mi-Kyung Chang

  • Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity.

    Peter X. Shaw;Sohvi Hörkkö;Mi-Kyung Chang;Linda K. Curtiss

  • Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell receptors and superantigen activity

    Marc Graille;Enrico A. Stura;Adam L. Corper;Brian J. Sutton

  • Rituximab therapy and autoimmune disorders: prospects for anti-B cell therapy

    Gregg J. Silverman;Stuart Weisman

  • Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal

    Doua Azzouz;Aidana Omarbekova;Adriana Heguy;Dominik Schwudke

  • Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory.

    Mi-Kyung Chang;Christoph J. Binder;Yury I. Miller;Ganesamoorthy Subbanagounder

  • Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus

    Amedeo Cappione;Jennifer H. Anolik;Aimee Pugh-Bernard;Jennifer Barnard

  • Protective Roles of Natural IgM Antibodies.

    Caroline Grönwall;Jaya Vas;Gregg J. Silverman

  • Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

    Aimee E. Pugh-Bernard;Gregg J. Silverman;Amedeo J. Cappione;Michael E. Villano

  • Programmed death-1 pathway in cancer and autoimmunity.

    Ariel Pedoeem;Inbar Azoulay-Alfaguter;Marianne Strazza;Gregg J. Silverman

  • Human-Derived Anti-Oxidized LDL Autoantibody Blocks Uptake of Oxidized LDL by Macrophages and Localizes to Atherosclerotic Lesions In Vivo

    Peter X. Shaw;Sohvi Hörkkö;Sotirios Tsimikas;Mi-Kyung Chang

  • Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation.

    Rosa Catera;Gregg J. Silverman;Katerina Hatzi;Till Seiler

  • Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigens.

    LE Silberstein;LC Jefferies;J Goldman;D Friedman

  • IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells.

    Yifang Chen;Yong Beom Park;Ekta Patel;Gregg J. Silverman

  • Roles of B cells in rheumatoid arthritis

    Gregg J Silverman;Dennis A Carson

  • Human IgA and IgG F(ab')2 that bind to staphylococcal protein A belong to the VHIII subgroup.

    E H Sasso;G J Silverman;M Mannik

  • Death by a B Cell Superantigen In Vivo VH-targeted Apoptotic Supraclonal B Cell Deletion by a Staphylococcal Toxin

    Carl S. Goodyear;Gregg J. Silverman

  • Human IgM molecules that bind staphylococcal protein A contain VHIII H chains.

    E H Sasso;G J Silverman;M Mannik

  • Immunological responses to oxidized LDL

    Sohvi Hörkkö;Christoph J Binder;Peter X Shaw;Mi-Kyung Chang

Frequent Co-Authors

Dennis A. Carson
Dennis A. Carson University of California, San Diego
Jill P. Buyon
Jill P. Buyon New York University
Thomas J. Kipps
Thomas J. Kipps University of California, San Diego
Maripat Corr
Maripat Corr University of California, San Diego
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
Dwight H. Kono
Dwight H. Kono Scripps Research Institute
Wulf Palinski
Wulf Palinski University of California, San Diego
Robert R. Clancy
Robert R. Clancy New York University
David L. Boyle
David L. Boyle University of California, San Diego
Victor J. Torres
Victor J. Torres New York University

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