World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
101
Citations
36782
World Ranking
706
National Ranking
403

Medicine

D-Index
102
Citations
37222
World Ranking
7680
National Ranking
3998

Research.com Recognitions

  • 2013 - Fellow, National Academy of Inventors
  • 2003 - Member of the National Academy of Sciences
  • 1995 - Fellow of the American Academy of Arts and Sciences

Overview

Dennis A. Carson is affiliated with the University of California, San Diego in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Within these areas, specific subfields of focus include Immunology, Molecular Biology, Biotechnology, Oncology, and Epidemiology.

The scientist's work addresses several main topics such as Immunotherapy and Immune Responses, Immune Response and Inflammation, Extracellular Vesicles in Disease, MicroRNA in Disease Regulation, RNA Interference and Gene Delivery, Microbial Inactivation Methods, and Wnt/β-catenin Signaling in Development and Cancer.

Some notable recent publications include:

  • "Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release" (2021, Frontiers in Pharmacology)
  • "Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22" (2020, Proceedings of the National Academy of Sciences)
  • "A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models" (2021, Molecular Cancer Therapeutics)
  • "Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model" (2023, Journal for ImmunoTherapy of Cancer)
  • "Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells" (2020, eLife)

Frequent publication venues where this scientist has contributed multiple articles include:

  • Frontiers in Pharmacology
  • Proceedings of the National Academy of Sciences
  • Frontiers in Immunology
  • ACS Chemical Biology
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaborators who have worked extensively with this scientist include:

  • Tomoko Hayashi
  • Howard B. Cottam
  • Shiyin Yao
  • Nikunj M. Shukla
  • Fumi Sato-Kaneko

Throughout their career, Dennis A. Carson has received several distinctions, including:

  • Fellow, National Academy of Inventors (2013)
  • Member of the National Academy of Sciences (2003)
  • Fellow of the American Academy of Arts and Sciences (1995)

Best Publications

  • Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

    Yukio Sato;Mark Roman;Helen Tighe;Delphine Lee

  • Effect of neuropeptides on production of inflammatory cytokines by human monocytes

    Martin Lotz;John H. Vaughan;Dennis A. Carson

  • Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants

    Mark Roman;Elena Martin-Orozco;Justin S. Goodman;Minh-Duc Nguyen

  • B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

    M Lotz;F Jirik;P Kabouridis;C Tsoukas

  • Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses

    E Raz;D A Carson;S E Parker;T B Parr

  • Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine.

    Lawrence D. Piro;Carlos J. Carrera;Dennis A. Carson;Ernest Beutler

  • Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization

    Eyal Raz;Helen Tighe;Yukio Sato;Maripat Corr

  • Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis.

    P A Guerne;B L Zuraw;J H Vaughan;D A Carson

  • Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells.

    F R Jirik;T J Podor;T Hirano;T Kishimoto

  • Substance P Activation of Rheumatoid Synoviocytes: Neural Pathway in Pathogenesis of Arthritis

    Martin Lotz;Dennis A. Carson;John H. Vaughan

  • Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

    M Corr;D J Lee;D A Carson;H Tighe

  • Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.

    S Seto;C J Carrera;M Kubota;D B Wasson

  • Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

    Dennis A. Carson;Jonathan Kaye;J. E. Seegmiller

  • Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

    C Terai;R S Kornbluth;C D Pauza;D D Richman

  • IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro.

    P A Guerne;D A Carson;M Lotz

  • Immunostimulatory polynucleotide/immunomodulatory molecule conjugates

    Dennis A. Carson;Eyal Raz;Mark Roman

  • DNA strand breaks, NAD metabolism, and programmed cell death

    Carson Da;Seto S;Wasson Db;Carrera Cj

  • Expression and function of wingless and frizzled homologs in rheumatoid arthritis

    Malini Sen;Kevin Lauterbach;Hani El-Gabalawy;Gary S. Firestein

  • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes

    DA Carson;DB Wasson;R Taetle;A Yu

  • Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.

    Davide Genini;Souichi Adachi;Qi Chao;David W. Rose

Frequent Co-Authors

Thomas J. Kipps
Thomas J. Kipps University of California, San Diego
John H. Vaughan
John H. Vaughan Scripps Health
Martin Lotz
Martin Lotz Scripps Research Institute
Gregg J. Silverman
Gregg J. Silverman New York University
Maripat Corr
Maripat Corr University of California, San Diego
Laura Z. Rassenti
Laura Z. Rassenti University of California, San Diego
Robert I. Fox
Robert I. Fox Scripps Health
Douglas D. Richman
Douglas D. Richman University of California, San Diego
Ernest Beutler
Ernest Beutler Scripps Research Institute
Philip L. Felgner
Philip L. Felgner University of California, Irvine

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