World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
114
Citations
46610
World Ranking
836
National Ranking
522

Research.com Recognitions

  • 2005 - Member of the National Academy of Medicine (NAM)

Overview

Dennis A. Carson is affiliated with the University of California, San Diego in the United States. Their research contributions span multiple disciplines, focusing primarily on biochemistry, genetics, molecular biology, immunology, microbiology, and medicine.

The main fields of study reflected in Carson's work include:

  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology
  • Medicine

Subfields where their publications are concentrated include:

  • Immunology
  • Molecular Biology
  • Biotechnology
  • Oncology
  • Epidemiology

Carson's research has addressed several significant topics, notably:

  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • Extracellular Vesicles in Disease
  • MicroRNA in Disease Regulation
  • RNA Interference and Gene Delivery
  • Microbial Inactivation Methods
  • Wnt/β-catenin Signaling in Development and Cancer

Among their recent publications are the following:

  • "Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release" (2021), published in Frontiers in Pharmacology
  • "Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22" (2020), published in Proceedings of the National Academy of Sciences
  • "A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models" (2021), published in Molecular Cancer Therapeutics
  • "Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model" (2023), published in Journal for ImmunoTherapy of Cancer
  • "Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells" (2020), published in eLife

The frequent co-authors collaborating with Carson include:

  • Tomoko Hayashi
  • Howard B. Cottam
  • Shiyin Yao
  • Nikunj M. Shukla
  • Fumi Sato-Kaneko

Publication venues where Carson has contributed multiple works are:

  • Frontiers in Pharmacology
  • Proceedings of the National Academy of Sciences
  • Frontiers in Immunology
  • ACS Chemical Biology
  • bioRxiv (Cold Spring Harbor Laboratory)

Among honors received, Carson was made a Member of the National Academy of Medicine in 2005.

Best Publications

  • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

    Tsutomu Nobori;Kaoru Miura;David J. Wu;Augusto Lois

  • Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

    Yukio Sato;Mark Roman;Helen Tighe;Delphine Lee

  • Effect of neuropeptides on production of inflammatory cytokines by human monocytes

    Martin Lotz;John H. Vaughan;Dennis A. Carson

  • Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7

    Jongdae Lee;Tsung-Hsien Chuang;Vanessa Redecke;Liping She

  • B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

    M Lotz;F Jirik;P Kabouridis;C Tsoukas

  • Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis.

    P A Guerne;B L Zuraw;J H Vaughan;D A Carson

  • Substance P Activation of Rheumatoid Synoviocytes: Neural Pathway in Pathogenesis of Arthritis

    Martin Lotz;Dennis A. Carson;John H. Vaughan

  • Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

    Desheng Lu;Yandong Zhao;Rommel Tawatao;Howard B. Cottam

  • Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females

    John Loughlin;Barbara Dowling;Kay Chapman;Lucy Marcelline

  • Inhibition of experimental asthma by indoleamine 2,3-dioxygenase

    Tomoko Hayashi;Lucinda Beck;Cyprian Rossetto;Xing Gong

  • Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

    Desheng Lu;Michael Y. Choi;Jian Yu;Januario E. Castro

  • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes

    DA Carson;DB Wasson;R Taetle;A Yu

  • Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.

    Davide Genini;Souichi Adachi;Qi Chao;David W. Rose

  • Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

    Tetsuya Fukuda;Liguang Chen;Tomoyuki Endo;Li Tang

  • The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

    Toshiro Moroishi;Tomoko Hayashi;Wei-Wei Pan;Yu Fujita

  • In vitro effects of Epstein-Barr virus on peripheral blood mononuclear cells from patients with rheumatoid arthritis and normal subjects.

    L Slaughter;D A Carson;F C Jensen;T L Holbrook

  • Activation of anti-hepatitis C virus responses via Toll-like receptor 7.

    Jongdae Lee;Christina C. N. Wu;Ki Jeong Lee;Tsung-Hsien Chuang

  • Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines

    Junko Ohata;Nathan J. Zvaifler;Mitsufumi Nishio;David L. Boyle

  • The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes.

    Darren Yang;Dissaya Pornpattananangkul;Teruaki Nakatsuji;Michael Chan

  • EFFECT OF NEUROPEPTIDES ON PRODUCTION OF INFLAMMATORY CYTOKINES BY HUMAN MONOCYTES

    M. Lotz

Frequent Co-Authors

Maripat Corr
Maripat Corr University of California, San Diego
Thomas J. Kipps
Thomas J. Kipps University of California, San Diego
Ingo G.H. Schmidt-Wolf
Ingo G.H. Schmidt-Wolf University Hospital Bonn
Richard J. Schwab
Richard J. Schwab University of Pennsylvania
Martin Lotz
Martin Lotz Scripps Research Institute
Christopher Patterson
Christopher Patterson Queen's University Belfast
Eyal Raz
Eyal Raz University of California, San Diego
Bruce L. Zuraw
Bruce L. Zuraw University of California, San Diego
Kelly A. Frazer
Kelly A. Frazer University of California, San Diego
Vineet Bafna
Vineet Bafna University of California, San Diego

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