John Thacker

Overview

Best Publications

• Mutation in Brca2 stimulates error‐prone homology‐directed repair of DNA double‐strand breaks occurring between repeated sequences

  Andrew Tutt;David Bertwistle;Janet Valentine;Anastasia Gabriel

  595
  Citations

• The RAD51 gene family, genetic instability and cancer

  John Thacker

  485
  Citations

• Effects of Radiations of Different Qualities on Cells: Molecular Mechanisms of Damage and Repair

  D.T. Goodhead;J. Thacker;R. Cox

  372
  Citations

• Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells.

  John Thacker;Albert Stretch;Miriam A. Stephens

  370
  Citations

• Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation.

  Carol S. Griffin;Paul J. Simpson;Caroline R. Wilson;John Thacker

  345
  Citations

• Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

  Bryan Deans;Carol S. Griffin;Mark Maconochie;John Thacker

  342
  Citations

• Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells

  Nigel J. Jones;Roger Cox;John Thacker

  293
  Citations

• The nature of mutants induced by ionising radiation in cultured hamster cells III. Molecular characterization of HPRT-deficient mutants induced by γ-rays or α-particles showing that the majority have deletions of all or part of the hprt gene

  John Thacker

  289
  Citations

• Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. IV. Biophysical interpretation.

  D.T. Goodhead;R.J. Munson;J. Thacker;R. Cox

  230
  Citations

• A surfeit of RAD51-like genes?

  John Thacker

  230
  Citations

• The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

  Richard Cartwright;Cathryn E. Tambini;Paul J. Simpson;John Thacker

  220
  Citations

• Mutation and inactivation of mammalian cells by various ionising radiations

  Roger Cox;John Thacker;D. T. Goodhead;R. J. Munson

  218
  Citations

• Inactivation and mutation of cultured mammalian cells by aluminium characteristic ultrasoft X-rays. II. Dose-responses of Chinese hamster and human diploid cells to aluminium X-rays and radiations of different LET.

  Roger Cox;John Thacker;D.T. Goodhead;W.K. Masson

  217
  Citations

• Effectiveness of 0·3 keV Carbon Ultrasoft X-rays for the Inactivation and Mutation of Cultured Mammalian Cells

  D.T. Goodhead;John Thacker;Roger Cox;R.E. Wilkinson

  200
  Citations

• The XRCC genes: expanding roles in DNA double-strand break repair

  John Thacker;Małgorzata Z. Zdzienicka

  187
  Citations

• Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine : polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals - One subfamily composed of l(2)35Aa is essential in Drosophila

  Tilo Schwientek;Eric P. Bennett;Carlos Flores;John Thacker

  183
  Citations

• Inactivation and Mutation of Cultured Mammalian Cells by Aluminium Characteristic Ultrasoft X-rays: I. Properties of Aluminium X-rays and Preliminary Experiments with Chinese Hamster Cells

  D.T. Goodhead;John Thacker

  182
  Citations

• The rejoining of double-strand breaks in DNA by human cell extracts

  Phillip North;Anil Ganesh;John Thacker

  178
  Citations

• The mammalian XRCC genes: their roles in DNA repair and genetic stability

  John Thacker;Małgorzata Z. Zdzienicka

  161
  Citations

• Formation of large deletions by illegitimate recombination in the HPRT gene of primary human fibroblasts.

  Tracy Morris;John Thacker

  156
  Citations