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Genetics

D-Index
68
Citations
16656
World Ranking
2432
National Ranking
307

Overview

Roger D. Cox is affiliated with the Medical Research Council in the United Kingdom. Their research contributions span the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with 42 and 35 publications respectively. The subfields of study mainly include Molecular Biology, Physiology, Cell Biology, Genetics, and Cardiology and Cardiovascular Medicine.

The scientist's work addresses multiple topics, notably Adipose Tissue and Metabolism, RNA Research and Splicing, Adipokines, Inflammation, and Metabolic Diseases, RNA modifications and cancer, Aldose Reductase and Taurine, Genetic Associations and Epidemiology, as well as Cardiomyopathy and Myosin Studies.

Frequently publishing in venues such as bioRxiv (Cold Spring Harbor Laboratory) and Zenodo (CERN European Organization for Nuclear Research), Roger D. Cox has contributed six papers each to these platforms. Additional publications appeared in Scientific Reports, JBMR Plus, and Endocrine Abstracts.

Co-authorship has been a notable part of their career, with frequent collaborators including Liz Bentley (13 papers), Marianne Yon (8 papers), Ramón Casero (7 papers), Melina Claussnitzer (6 papers), and Rebecca Dumbell (6 papers).

Among their recent scientific papers are the following:

  • A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density, 2021, Cell Metabolism
  • Mylk3null C57BL/6N mice develop cardiomyopathy, whereas Nntnull C57BL/6J mice do not, 2020, Life Science Alliance
  • Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo, 2021, Science Advances
  • The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, 2020, American Journal of Physiology-Gastrointestinal and Liver Physiology
  • A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes, 2020, Mammalian Genome

Best Publications

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Overexpression of Fto leads to increased food intake and results in obesity.

    Chris Church;Lee Moir;Fiona McMurray;Christophe Girard

  • A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

    A. A. Toye;J. D. Lippiat;P. Proks;K. Shimomura

  • A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human

    Reza M Salek;Mahon L Maguire;Elizabeth Bentley;Denis V. Rubtsov

  • Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma.

    Youming Zhang;Nicholas I Leaves;Gavin G Anderson;Chris P Ponting

  • A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

    Chris Church;Sheena Lee;Eleanor A. L. Bagg;James S. McTaggart

  • Effects of Radiations of Different Qualities on Cells: Molecular Mechanisms of Damage and Repair

    D.T. Goodhead;J. Thacker;R. Cox

  • Deletion of Nicotinamide Nucleotide Transhydrogenase: A New Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice

    Helen C. Freeman;Alison Hugill;Neil T. Dear;Frances M. Ashcroft

  • The expression of myosin genes in developing skeletal muscle in the mouse embryo.

    G E Lyons;M Ontell;R Cox;D Sassoon

  • Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.

    E.L. Duncan;P. Danoy;J.P. Kemp;P.J. Leo

  • A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

    Patrick E. MacDonald;Patrick E. MacDonald;Yang Zhang De Marinis;Reshma Ramracheya;S Albert Salehi

  • Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells

    Nigel J. Jones;Roger Cox;John Thacker

  • Cloning of a novel member of the low-density lipoprotein receptor family.

    Patricia J. Hey;Rebecca C.J. Twells;Michael S. Phillips;Yusuke Nakagawa

  • Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.

    S. D. Brown;R. C. J. Twells;P. J. Hey;R. D. Cox

  • Human muscle neural cell adhesion molecule (N-CAM): Identification of a muscle-specific sequence in the extracellular domain

    George Dickson;Hilary J. Gower;C.Howard Barton;Howard M. Prentice

  • The European dimension for the mouse genome mutagenesis program

    Johan Auwerx;Phil Avner;Richard Baldock;Andrea Ballabio

  • A gene-driven approach to the identification of ENU mutants in the mouse.

    Emma L. Coghill;Alison Hugill;Nick Parkinson;Claire Davison

  • FTO influences adipogenesis by regulating mitotic clonal expansion.

    Myrte Merkestein;Samantha Laber;Fiona McMurray;Daniel Andrew

  • Inactivation and mutation of cultured mammalian cells by aluminium characteristic ultrasoft X-rays. II. Dose-responses of Chinese hamster and human diploid cells to aluminium X-rays and radiations of different LET.

    Roger Cox;John Thacker;D.T. Goodhead;W.K. Masson

  • ENU mutagenesis, a way forward to understand gene function.

    Abraham Acevedo-Arozena;Sara Wells;Paul Potter;Michelle Kelly

Frequent Co-Authors

Rajesh V. Thakker
Rajesh V. Thakker University of Oxford
Frances M. Ashcroft
Frances M. Ashcroft University of Oxford
Steve D.M. Brown
Steve D.M. Brown Medical Research Council
Matthew A. Brown
Matthew A. Brown Guy's and St Thomas' NHS Foundation Trust
Quentin M. Anstee
Quentin M. Anstee Newcastle University
Mark Thursz
Mark Thursz Imperial College London
Dominique Gauguier
Dominique Gauguier McGill University
Robert D. Goldin
Robert D. Goldin Imperial College London
Michel Marre
Michel Marre Université Paris Cité
Hans Lehrach
Hans Lehrach Max Planck Society

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