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Genetics

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113
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Molecular Biology

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113
Citations
50726
World Ranking
328
National Ranking
196

Research.com Recognitions

  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2015 - Member of the National Academy of Sciences

Overview

Maria Jasin is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Within these fields, their work is focused on Molecular Biology as well as Oncology, Genetics, Plant Science, and Cancer Research.

The scientist's main topics of study include DNA Repair Mechanisms, CRISPR and Genetic Engineering, PARP inhibition in cancer therapy, Genomics and Chromatin Dynamics, Pluripotent Stem Cells Research, Chromosomal and Genetic Variations, and RNA and protein synthesis mechanisms.

Maria Jasin has published extensively in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Molecular Cell
  • Proceedings of the National Academy of Sciences
  • Nature

Their recent papers include:

  • Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos, 2020, Cell
  • Ensuring meiotic DNA break formation in the mouse pseudoautosomal region, 2020, Nature
  • Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex, 2021, Nature Communications
  • De novo deletions and duplications at recombination hotspots in mouse germlines, 2021, Cell
  • BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair, 2024, Molecular Cell

Frequent collaborators in their research include:

  • Travis White
  • Rohit Prakash
  • Pei Xin Lim
  • Kara A. Bernstein
  • Scott Keeney

Maria Jasin has been recognized by election to notable organizations including being named a Fellow of the American Academy of Arts and Sciences in 2017 and a Member of the National Academy of Sciences in 2015.

Best Publications

  • Brca1 controls homology-directed DNA repair.

    Mary Ellen Moynahan;Joanne W Chiu;Beverly H Koller;Maria Jasin

  • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

    Andrew J. Pierce;Roger D. Johnson;Larry H. Thompson;Maria Jasin

  • Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11

    Katharina Schlacher;Nicole Christ;Nicolas Siaud;Akinori Egashira

  • BRCA2 is required for homology-directed repair of chromosomal breaks.

    Mary Ellen Moynahan;Andrew J Pierce;Maria Jasin

  • Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

    Mary Ellen Moynahan;Maria Jasin

  • Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

    Bing Xia;Qing Sheng;Koji Nakanishi;Akihiro Ohashi

  • Repair of strand breaks by homologous recombination.

    Maria Jasin;Rodney Rothstein

  • Recombinational DNA double-strand breaks in mice precede synapsis

    Shantha K. Mahadevaiah;James M.A. Turner;Frédéric Baudat;Emmy P. Rogakou

  • Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.

    P Rouet;F Smih;M Jasin

  • A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

    Katharina Schlacher;Hong Wu;Maria Jasin

  • Homology-directed repair is a major double-strand break repair pathway in mammalian cells

    Feng Liang;Mingguang Han;Peter J. Romanienko;Maria Jasin

  • Sister chromatid gene conversion is a prominent double‐strand break repair pathway in mammalian cells

    Roger D. Johnson;Maria Jasin

  • Chromosome Synapsis Defects and Sexually Dimorphic Meiotic Progression in Mice Lacking Spo11

    Frédéric Baudat;Katia Manova;Julie Pui Yuen;Maria Jasin

  • Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

    Rohit Prakash;Yu Zhang;Weiran Feng;Maria Jasin

  • Frequent chromosomal translocations induced by DNA double-strand breaks

    Christine Richardson;Maria Jasin

  • Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

    Philippe Rouet;Fatima Smih;Maria Jasin

  • Enhancers and eukaryotic gene transcription

    Edgar Serfling;Maria Jasin;Walter Schaffner

  • Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

    Andrew J. Pierce;Peng Hu;Mingguang Han;Nathan Ellis

  • Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.

    Courtney A. Lovejoy;Wendi Li;Steven Reisenweber;Supawat Thongthip

  • Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations

    Christine Richardson;Mary Ellen Moynahan;Maria Jasin

Frequent Co-Authors

Scott Keeney
Scott Keeney Memorial Sloan Kettering Cancer Center
Koji Nakanishi
Koji Nakanishi Columbia University
Richard Baer
Richard Baer Columbia University
Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio
Stephen C. West
Stephen C. West The Francis Crick Institute
Roland Kanaar
Roland Kanaar Erasmus University Rotterdam
Razqallah Hakem
Razqallah Hakem University of Toronto
Simon N. Powell
Simon N. Powell Memorial Sloan Kettering Cancer Center
Clare L. Scott
Clare L. Scott Walter and Eliza Hall Institute of Medical Research
Hong Wu
Hong Wu Peking University

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