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Necil Kutukculer

Necil Kutukculer

D-Index & Metrics

Immunology

D-Index
43
Citations
7879
World Ranking
4837
National Ranking
4

Overview

Necil Kutukculer is affiliated with Ege University in Turkey and has an extensive research portfolio in medicine, biochemistry, genetics, and molecular biology. Their work primarily intersects with immunology and microbiology, with a particular focus on immunodeficiency and autoimmune disorders. Kutukculer's research also encompasses blood disorders and treatments, diabetes and associated disorders, cytomegalovirus and herpesvirus research, platelet disorders, immune cell function and interaction, and inflammasome and immune disorders.

Their scholarly output includes significant publications in reputable journals, with recurring contributions to the Journal of Clinical Immunology and Case Reports in Immunology, as well as notable work appearing in the Journal of Allergy and Clinical Immunology, Immunologic Research, and International Archives of Allergy and Immunology.

Recent research papers authored or co-authored by Kutukculer include:

  • Consensus Middle East and North Africa Registry on Inborn Errors of Immunity, 2021, Journal of Clinical Immunology
  • Therapeutic modalities and clinical outcomes in a large cohort with LRBA deficiency and CTLA4 insufficiency, 2023, Journal of Allergy and Clinical Immunology
  • Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia, 2021, Journal of Clinical Immunology
  • Comparing the levels of CTLA-4-dependent biological defects in patients with LRBA deficiency and CTLA-4 insufficiency, 2022, Allergy
  • Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry, 2022, Clinical Immunology

Frequently collaborating with other researchers, Kutukculer has worked closely with Neslihan Edeer Karaca, Güzide Aksu, Ezgi Topyıldız, Nesrin Gülez, and Ayça Aykut. These collaborations have contributed to advancing the understanding of immune system dysregulation and related therapeutic approaches.

Their research spans several subfields of study, including immunology, genetics, molecular biology, epidemiology, and pulmonary and respiratory medicine. The diverse subfield expertise supports a broad investigation into immune-related diseases and genetic factors impacting patient outcomes.

Best Publications

  • Clinical picture and treatment of 2212 patients with common variable immunodeficiency

    Benjamin Gathmann;Nizar Mahlaoui;Laurence Gérard;Eric Oksenhendler

  • Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

    Karin R. Engelhardt;Sean McGhee;Sabine Winkler;Atfa Sassi

  • Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries

    Ludovic de Beaucoudrey;Arina Samarina;Arina Samarina;Arina Samarina;Jacinta Bustamante;Jacinta Bustamante;Aurélie Cobat;Aurélie Cobat

  • Low Penetrance, Broad Resistance, and Favorable Outcome of Interleukin 12 Receptor β1 Deficiency Medical and Immunological Implications

    Claire Fieschi;Stéphanie Dupuis;Emilie Catherinot;Jacqueline Feinberg

  • DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

    Susanne E. Aydin;Sara Sebnem Kilic;Caner Aytekin;Ashish Kumar

  • X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production

    Orchidée Filipe-Santos;Jacinta Bustamante;Margje H. Haverkamp;Margje H. Haverkamp;Emilie Vinolo

  • DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

    Haifa H. Jabara;Douglas R. McDonald;Erin Janssen;Michel J. Massaad

  • Inherited and acquired immunodeficiencies underlying tuberculosis in childhood.

    Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Jacinta Bustamante;Jamila El-Baghdadi;Yildiz Camcioglu

  • The extended clinical phenotype of 64 patients with dedicator of cytokinesis 8 deficiency.

    Karin R. Engelhardt;Karin R. Engelhardt;Karin R. Engelhardt;Michael E. Gertz;Sevgi Keles;Sevgi Keles;Alejandro A. Schäffer

  • Serum immunoglobulin (IgG, IgM, IgA) and IgG subclass concentrations in healthy children: a study using nephelometric technique.

    Güzide Aksu;Ferah Genel;Güldane Koturoğlu;Zafer Kurugöl

  • BCG-osis and tuberculosis in a child with chronic granulomatous disease

    Jacinta Bustamante;Guzide Aksu;Guillaume Vogt;Ludovic de Beaucoudrey

  • Study of pro-inflammatory (TNF-alpha, IL-1alpha, IL-6) and T-cell-derived (IL-2, IL-4) cytokines in plasma and synovial fluid of patients with juvenile chronic arthritis: correlations with clinical and laboratory parameters.

    N Kutukculer;S Caglayan;F Aydogdu

  • Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score

    Victoria Katharina Tesch;Hassan Abolhassani;Hassan Abolhassani;Bella Shadur;Bella Shadur;Joachim Zobel

  • Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency.

    Ayca Kiykim;Ismail Ogulur;Esra Dursun;Louis Marie Charbonnier

  • IL-12Rβ1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey.

    Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Jamila El Baghdadi;Nima Parvaneh;Aziz Bousfiha

  • Mycobacterial disease in patients with chronic granulomatous disease: A retrospective analysis of 71 cases

    Francesca Conti;Francesca Conti;Francesca Conti;Saul Oswaldo Lugo-Reyes;Saul Oswaldo Lugo-Reyes;Lizbeth Blancas Galicia;Lizbeth Blancas Galicia;Jianxin He

  • Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation

    M. Teresa de la Morena;David Leonard;Troy R. Torgerson;Otavio Cabral-Marques

  • Gingival Crevicular Fluid Levels of Cathelicidin LL-37 and Interleukin-18 in Patients With Chronic Periodontitis

    Oya Türkoğlu;Gülnur Emingil;Necil Kütükçüler;Gül Atilla

  • Defects along the TH17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome

    Shadi Al Khatib;Sevgi Keles;Maria Garcia-Lloret;Elif Karakoc-Aydiner

  • Clinical Features of Candidiasis in Patients With Inherited Interleukin 12 Receptor β1 Deficiency

    Monia Ouederni;Ozden Sanal;Aydan Ikincioğullari;Ilhan Tezcan

  • Proinflammatory cytokines, prostaglandins and zinc in febrile convulsions

    Sarenur Tütüncüoğlu;Necil Kütükçüler;Lütfü Kepe;Canan Çoker

  • The Prevalances and Patient Characteristics of Primary Immunodeficiency Diseases in Turkey—Two Centers Study

    Sara S. Kilic;Mustafa Ozel;Demet Hafizoglu;Neslihan Edeer Karaca

Frequent Co-Authors

Bodo Grimbacher
Bodo Grimbacher University of Freiburg
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Laurent Abel
Laurent Abel Université Paris Cité
Sevgi Keles
Sevgi Keles Necmettin Erbakan University
Jacinta Bustamante
Jacinta Bustamante Rockefeller University
Talal A. Chatila
Talal A. Chatila Boston Children's Hospital
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Waleed Al-Herz
Waleed Al-Herz Kuwait University

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