World's Best Scientists 2026 revealed!
Hugo Vanderstichele

Hugo Vanderstichele

D-Index & Metrics

Neuroscience

D-Index
76
Citations
27108
World Ranking
1898
National Ranking
17

Overview

Hugo Vanderstichele is affiliated with Fujirebio (Belgium) and has contributed extensively to research in medicine, focusing primarily on physiology, psychiatry and mental health, neurology, molecular biology, and statistics and probability.

The research topics covered by their work include:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Parkinson's Disease Mechanisms and Treatments
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Statistical Methods in Clinical Trials
  • S100 Proteins and Annexins
  • Neurological disorders and treatments

Vanderstichele's publication record includes numerous papers, with notable recent works such as:

  • Acceptable performance of blood biomarker tests of amyloid pathology - recommendations from the Global CEO Initiative on Alzheimer's Disease, 2024, Nature Reviews Neurology
  • Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease, 2021, Translational Psychiatry
  • The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid β and tau, 2021, Alzheimer's & Dementia
  • Combination of plasma amyloid beta(1-42/1-40) and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology, 2020, Alzheimer's Research & Therapy
  • How specific are the conformation-specific α-synuclein antibodies? Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized preparations of α-synuclein monomers, fibrils and oligomers with distinct structures and morphology, 2020, Neurobiology of Disease

The most frequent publication venues for their work include:

  • Alzheimer's & Dementia
  • Alzheimer's Research & Therapy
  • The Journal of Prevention of Alzheimer's Disease
  • Clinical Chemistry and Laboratory Medicine (CCLM)
  • Translational Psychiatry

Frequent collaborators in their research projects are:

  • Erik Stoops
  • Charlotte E. Teunissen
  • Kaj Blennow
  • Inge M.W. Verberk
  • Henrik Zetterberg

Best Publications

  • Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.

    Leslie M. Shaw;Hugo Vanderstichele;Malgorzata Knapik-Czajka;Christopher M. Clark

  • Improved discrimination of AD patients using beta-amyloid((1-42)) and tau levels in CSF

    F Hulstaert;K Blennow;A Ivanoiu;HC Schoonderwaldt

  • Cerebrospinal Fluid β-Amyloid(1-42) in Alzheimer Disease: Differences Between Early- and Late-Onset Alzheimer Disease and Stability During the Course of Disease

    Niels Andreasen;Camilla Hesse;Pia Davidsson;Lennart Minthon

  • Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice

    Niels Andreasen;Lennart Minthon;Pia Davidsson;Eugeen Vanmechelen

  • Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

    An Herreman;Dieter Hartmann;Wim Annaert;Paul Saftig

  • Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study.

    Harald Hampel;Katharina Buerger;Raymond Zinkowski;Stefan J. Teipel

  • Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization.

    E Vanmechelen;H Vanderstichele;P Davidsson;E Van Kerschaver

  • Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke.

    Camilla Hesse;Lars Rosengren;Niels Andreasen;Pia Davidsson

  • Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People

    Geert De Meyer;Fred Shapiro;Hugo Vanderstichele;Eugeen Vanmechelen

  • Tau and Abeta42 in cerebrospinal fluid from healthy adults 21-93 years of age: establishment of reference values.

    Magnus Sjögren;Hugo Vanderstichele;Hans Ågren;Olof Zachrisson

  • Simultaneous Measurement of β-Amyloid(1–42), Total Tau, and Phosphorylated Tau (Thr181) in Cerebrospinal Fluid by the xMAP Technology

    Annika Olsson;Hugo Vanderstichele;Niels Andreasen;Geert De Meyer

  • CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease

    Shorena Janelidze;Henrik Zetterberg;Niklas Mattsson;Sebastian Palmqvist

  • Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative.

    Hugo Vanderstichele;Mirko Bibl;Sebastiaan Engelborghs;Nathalie Le Bastard

  • The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

    Niklas Mattsson;Ulf Andreasson;Staffan Persson;Hiroyuki Arai

  • Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease.

    Pratishtha Chatterjee;Pratishtha Chatterjee;Steve Pedrini;Erik Stoops;Kathryn Goozee

  • Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI

    Leslie M. Shaw;Hugo Vanderstichele;Malgorzata Knapik-Czajka;Michal Figurski

  • Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.

    H Vanderstichele;E Van Kerschaver;C Hesse;P Davidsson

  • Evaluation of plasma A beta(40) and A beta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment

    Oskar Hansson;Oskar Hansson;Henrik Zetterberg;Eugeen Vanmechelen;Hugo Vanderstichele

  • Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment

    N Andreasen;Lennart Minthon;E Vanmechelen;H Vanderstichele

  • Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia.

    Sebastiaan Engelborghs;Karen De Vreese;Tom Van de Casteele;Hugo Vanderstichele

  • Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative

    H. Vanderstichele;M. Bibl;S. Engelborghs;N. Le Bastard

Frequent Co-Authors

Kaj Blennow
Kaj Blennow University of Gothenburg
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Ulf Andreasson
Ulf Andreasson University of Gothenburg
Erik Portelius
Erik Portelius Sahlgrenska University Hospital
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Brit Mollenhauer
Brit Mollenhauer University of Göttingen
Shorena Janelidze
Shorena Janelidze Lund University
Kevin Taddei
Kevin Taddei Edith Cowan University

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