World's Best Scientists 2026 revealed!
Eugeen Vanmechelen

Eugeen Vanmechelen

D-Index & Metrics

Medicine

D-Index
86
Citations
28069
World Ranking
14102
National Ranking
176

Overview

Eugeen Vanmechelen is affiliated with Fujirebio in Belgium and has an extensive research background primarily focused on medicine with a concentration in neurodegenerative diseases. Their published work spans several subfields including physiology, psychiatry and mental health, molecular biology, neurology, as well as radiology, nuclear medicine, and imaging.

Their research addresses key topics such as Alzheimer's disease research and treatments, dementia and cognitive impairment research, neuroscience and neuropharmacology, amyloidosis diagnosis and treatment, medical imaging techniques, prion diseases and protein misfolding, and cancer-related cognitive impairment studies.

Vanmechelen has contributed to multiple recent papers including:

  • Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology, 2021, Acta Neuropathologica
  • The β-Secretase BACE1 in Alzheimer's Disease, 2020, Biological Psychiatry
  • Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology, 2024, JAMA Neurology
  • Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease, 2022, Brain
  • Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are detected, 2020, EMBO Molecular Medicine

Frequent collaborators include Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Thomas K. Karikari, and Erik Stoops.

Their research has been published in notable journals and venues such as:

  • Alzheimer's & Dementia
  • Alzheimer's Research & Therapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Medicine
  • Biological Psychiatry

Vanmechelen's work integrates comprehensive biochemical and molecular approaches to better understand pathological mechanisms and develop biomarkers for early diagnosis and progression monitoring of Alzheimer's disease and related dementias.

Best Publications

  • Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?

    K. Blennow;A. Wallin;H. Ågren;C. Spenger

  • Improved discrimination of AD patients using beta-amyloid((1-42)) and tau levels in CSF

    F Hulstaert;K Blennow;A Ivanoiu;HC Schoonderwaldt

  • Cerebrospinal Fluid β-Amyloid(1-42) in Alzheimer Disease: Differences Between Early- and Late-Onset Alzheimer Disease and Stability During the Course of Disease

    Niels Andreasen;Camilla Hesse;Pia Davidsson;Lennart Minthon

  • Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice

    Niels Andreasen;Lennart Minthon;Pia Davidsson;Eugeen Vanmechelen

  • Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology

    Nicholas J. Ashton;Tharick A. Pascoal;Thomas K. Karikari;Andréa L. Benedet;Andréa L. Benedet

  • Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205

    M. Goedert;R. Jakes;E. Vanmechelen

  • The β-Secretase BACE1 in Alzheimer's Disease.

    Harald Hampel;Robert Vassar;Bart De Strooper;Bart De Strooper;Bart De Strooper;John Hardy

  • Detection of Proteins in Normal and Alzheimer's Disease Cerebrospinal Fluid with a Sensitive Sandwich Enzyme‐Linked Immunosorbent Assay

    Marc Vandermeeren;Marc Vandermeeren;Marc Mercken;Marc Mercken;Eugeen Vanmechelen;Jan Six;Jan Six

  • Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study.

    Harald Hampel;Katharina Buerger;Raymond Zinkowski;Stefan J. Teipel

  • Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization.

    E Vanmechelen;H Vanderstichele;P Davidsson;E Van Kerschaver

  • Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke.

    Camilla Hesse;Lars Rosengren;Niels Andreasen;Pia Davidsson

  • A Practical Guide to Immunoassay Method Validation

    Ulf Andreasson;Armand Perret-Liaudet;Linda J C van Waalwijk van Doorn;Kaj Blennow

  • Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People

    Geert De Meyer;Fred Shapiro;Hugo Vanderstichele;Eugeen Vanmechelen

  • Tau and Abeta42 in cerebrospinal fluid from healthy adults 21-93 years of age: establishment of reference values.

    Magnus Sjögren;Hugo Vanderstichele;Hans Ågren;Olof Zachrisson

  • Simultaneous Measurement of β-Amyloid(1–42), Total Tau, and Phosphorylated Tau (Thr181) in Cerebrospinal Fluid by the xMAP Technology

    Annika Olsson;Hugo Vanderstichele;Niels Andreasen;Geert De Meyer

  • Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders

    Sara Hall;Annika Öhrfelt;Radu Constantinescu;Ulf Andreasson

  • Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease : identification of phosphorylation sites in tau-protein

    M Goedert;R Jakes;R A Crowther;P Cohen

  • Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.

    H Vanderstichele;E Van Kerschaver;C Hesse;P Davidsson

  • CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease.

    Kaj Blennow;Eugeen Vanmechelen;Harald Hampel

  • Evaluation of plasma A beta(40) and A beta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment

    Oskar Hansson;Oskar Hansson;Henrik Zetterberg;Eugeen Vanmechelen;Hugo Vanderstichele

Frequent Co-Authors

Kaj Blennow
Kaj Blennow University of Gothenburg
Hugo Vanderstichele
Hugo Vanderstichele Fujirebio (Belgium)
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Sebastiaan Engelborghs
Sebastiaan Engelborghs University of Antwerp
Harald Hampel
Harald Hampel Eisai (United States)
Niels Andreasen
Niels Andreasen Karolinska University Hospital
Patrick Cras
Patrick Cras University of Antwerp
Anders Wallin
Anders Wallin University of Gothenburg
Lennart Minthon
Lennart Minthon Lund University
Bruno Dubois
Bruno Dubois Université Paris Cité

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re exploring a career in medicine, there are numerous alternative and supporting fields worth considering. Many students pursue programs in healthcare that offer flexible online study options and varied entry requirements.

For those interested in the administrative side of healthcare, earning a degree from one of the medical billing and coding schools that accept fafsa can open doors to in-demand roles. These programs often qualify for federal financial aid, making your educational journey more affordable.

Nursing remains a top career path for aspiring healthcare professionals. If standardized tests are a concern, look into nursing programs without teas to find options with fewer admission barriers.

Leadership roles are also within reach with an online healthcare management degree, preparing graduates to oversee clinics, hospitals, or entire healthcare systems.

Registered nurses looking to grow their credentials can benefit from adn to msn bridge programs, which streamline the path to advanced nursing practice and leadership positions.

Best Scientists Citing Eugeen Vanmechelen

Trending Scientists

Recently Published Articles