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Joris J. T. H. Roelofs

Joris J. T. H. Roelofs

D-Index & Metrics

Immunology

D-Index
54
Citations
10448
World Ranking
3896
National Ranking
151

Overview

Joris J. T. H. Roelofs is affiliated with the University of Amsterdam in the Netherlands. Their research primarily spans the field of Medicine, with a focus on several subfields including Pulmonary and Respiratory Medicine, Nephrology, Surgery, Immunology, and Molecular Biology.

Roelofs's recent papers demonstrate involvement in a variety of medical topics and collaborations with multiple co-authors. Notable recent publications include:

  • "Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study" (2020), The Lancet Microbe
  • "Deep learning-based classification of kidney transplant pathology: a retrospective, multicentre, proof-of-concept study" (2021), The Lancet Digital Health
  • "Bronchial Thermoplasty Induced Airway Smooth Muscle Reduction and Clinical Response in Severe Asthma. The TASMA Randomized Trial" (2020), American Journal of Respiratory and Critical Care Medicine
  • "Consensus definitions for glomerular lesions by light and electron microscopy: recommendations from a working group of the Renal Pathology Society" (2020), Kidney International
  • "Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM-1" (2022), EMBO Reports

The topics of research explored in their work include:

  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Immune Response and Inflammation
  • Renal Diseases and Glomerulopathies
  • Chronic Kidney Disease and Diabetes
  • Congenital gastrointestinal and neural anomalies
  • Renal and Vascular Pathologies
  • Intestinal Malrotation and Obstruction Disorders

Frequent co-authors associated with Joris J. T. H. Roelofs are:

  • Sandrine Florquin
  • Alex F. de Vos
  • Jesper Kers
  • Tom van der Poll
  • Alessandra Tammaro

The scientist regularly publishes in several medical journals, with multiple contributions to:

  • Nephrology Dialysis Transplantation
  • Journal of the American Society of Nephrology
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Intensive Care Medicine Experimental

Joris J. T. H. Roelofs's work encompasses detailed studies in pathology, immunology, respiratory medicine, and renal research, reflecting a multidisciplinary approach within clinical and translational medicine.

Best Publications

  • The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

    Tim J Schuijt;Jacqueline M Lankelma;Brendon P Scicluna;Felipe de Sousa e Melo

  • Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study.

    Bernadette Schurink;Eva Roos;Teodora Radonic;Ellis Barbe

  • Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury

    Wilco P. Pulskens;Gwendoline J. Teske;Loes M. Butter;Joris J. Roelofs

  • Thrombocytopenia impairs host defense in gram-negative pneumonia–derived sepsis in mice

    Sacha F. de Stoppelaar;Cornelis van ’t Veer;Theodora A. M. Claushuis;Bregje J. A. Albersen

  • Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps

    Marcel P.B. Jansen;Diba Emal;Gwendoline J.D. Teske;Mark C. Dessing

  • Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis.

    Rosemarijn Renckens;Joris J. T. H. Roelofs;Sandrine Florquin;Alex F. de Vos

  • A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent

    Tim J. Schuijt;Tim J. Schuijt;Tim J. Schuijt;Jeroen Coumou;Jeroen Coumou;Sukanya Narasimhan;Jianfeng Dai

  • Protection against Renal Ischemia Reperfusion Injury by CD44 Disruption

    Kasper M. A. Rouschop;Joris J.T.H. Roelofs;Nike Claessen;Paula da Costa Martins

  • Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome

    Maria T Kuipers;Hamid Aslami;John R Janczy;Koenraad F van der Sluijs

  • Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia.

    Rosemarijn Renckens;Joris J T H Roelofs;Peter I Bonta;Sandrine Florquin

  • CD44 Deficiency Increases Tubular Damage But Reduces Renal Fibrosis in Obstructive Nephropathy

    Kasper M A Rouschop;Miguel E Sewnath;Nike Claessen;Joris J T H Roelofs

  • Role of Peptidylarginine Deiminase 4 in Neutrophil Extracellular Trap Formation and Host Defense during Klebsiella pneumoniae- Induced Pneumonia-Derived Sepsis.

    Theodora A. M. Claushuis;Lieve E. H. van der Donk;Anna L. Luitse;Henk A. van Veen

  • Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model

    Alexander P. J. Vlaar;Jorrit J. Hofstra;Wim Kulik;Henk van Lenthe

  • The role of platelets in acute kidney injury.

    Marcel P. B. Jansen;Sandrine Florquin;Joris J. T. H. Roelofs

  • Tissue-Type Plasminogen Activator Modulates Inflammatory Responses and Renal Function in Ischemia Reperfusion Injury

    Joris J.T.H. Roelofs;Kasper M.A. Rouschop;Jaklien C. Leemans;Nike Claessen

  • Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria

    Theodora A.M. Claushuis;Alex F. de Vos;Bernhard Nieswandt;Louis Boon

  • iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling

    Xiaoping Qing;Yurii Chinenov;Patricia Redecha;Michael Madaio

  • The Acute-Phase Response and Serum Amyloid A Inhibit the Inflammatory Response to Acinetobacter baumannii Pneumonia

    Rosemarijn Renckens;Joris J. T. H. Roelofs;Sylvia Knapp;Alex F. de Vos

  • MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei

    W. Joost Wiersinga;Catharina W. Wieland;Joris J. T. H. Roelofs;Tom van der Poll

  • Neutrophils are essential for rapid clearance of Enterococcus faecium in mice.

    Masja Leendertse;Rob J. L. Willems;Ida A. J. Giebelen;Joris J. T. H. Roelofs

  • Inflammation patterns induced by different Burkholderia species in mice.

    W. Joost Wiersinga;Alex F. de Vos;Regina de Beer;Catharina W. Wieland

Frequent Co-Authors

Tom van der Poll
Tom van der Poll University of Amsterdam
Sandrine Florquin
Sandrine Florquin University of Amsterdam
Cornelis van 't Veer
Cornelis van 't Veer University of Amsterdam
Marcus J. Schultz
Marcus J. Schultz University of Amsterdam
Alex F. de Vos
Alex F. de Vos University of Amsterdam
Marcel Levi
Marcel Levi University of Amsterdam
Joost C. M. Meijers
Joost C. M. Meijers University of Amsterdam
Ineke J. M. ten Berge
Ineke J. M. ten Berge University of Amsterdam
Louis Boon
Louis Boon University of Amsterdam
Nicholas P. J. Day
Nicholas P. J. Day University of Oxford

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